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Saxenda and Fatigue: What Users Say (Page 3)

Reviews for Saxenda

Commonly mentioned side effects
  • Hun...
  • Taken for less than 1 month
  • October 14, 2015

For Weight Loss (Obesity/Overweight) "When I started a week ago, I was 294, and I’m 5’10. I was nervous about the needle, but the truth is you can hardly feel it, it’s that thin. I started at .6, and after a few days, I went up to 1.2. The other day, I tried to go to 1.8, but I had a serious stomach ache all night long, so I went back to 1.2. At 1.2, the side effects are mild: headaches, a little nausea, slight rough throat, and fatigue. I have lost 10 pounds in this week with minimal exercise, perhaps 10/15 minutes on the elliptical a night and some free weights. I’m in love with this product. I have ZERO appetite. I have to force myself to eat, and even then, I end up eating two bites and throwing the rest away. I’m very hopeful this is the motivation I needed and that it continues to work."

8 / 10
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  • Chr...
  • Taken for 1 to 6 months
  • July 28, 2018

For Weight Loss (Obesity/Overweight) "I started taking Saxenda in April. So it’s been 4 months and I lost 22 pounds. I am 5’5”, 53 years old, and I weighed 184 lb when I started and now weigh 162 lb. I felt sluggish the first week but nothing horrible. I took the shot at night, so I didn’t have any nausea. I have no real side effects to speak of. I can still drink alcohol when I want to without any issues. I went down 2 pants sizes, and I feel great. Weight loss has slowed down a bit the last few weeks, but I am still losing."

10 / 10
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  • Dee...
  • Taken for 1 to 6 months
  • January 25, 2019

For Weight Loss (Obesity/Overweight) "I started taking Saxenda on November 16, 2018. My doctor warned me I might experience some nausea at first, but if I could tolerate it, to keep taking the medicine. Boy, that was an understatement. During the first week of taking Saxenda, I felt like I was going to die. I had extreme nausea, diarrhea, and fatigue. I had absolutely zero energy and had to take off from work for the week! But after the first two weeks, the symptoms subsided. Currently, I am eating around 1,000 - 1,200 cal a day. I have zero appetite and zero cravings (which is new for me). I am down 25 pounds in two months. Although I'm still very fatigued, I will continue to take Saxenda and feel that the side effects in the beginning are worth it if you have a substantial amount of weight to lose."

8 / 10
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Frequently asked questions

  • Anonymous
  • Taken for 1 to 6 months
  • March 27, 2018

For Weight Loss (Obesity/Overweight) "My doctor started me on samples about a year and a half ago. In two months, I went from 260 lbs to 222 lbs. It was awesome! I felt great, had slight nausea and diarrhea the first three days, and then it was gone. Well, I fought my husband’s insurance (with the help of my doctor), and it wasn’t approved, so I had to stop. In over a year, I only gained back 20 lbs! I have a new job, and my insurance covers Saxenda. Yippee! I just started the 2.4 dose, and I’m already down 14 lbs. However, I’m having a hard time eating. I literally eat just enough so I’m not nauseous from an empty stomach. The thought of any food turns my stomach, and I’m a bit sluggish because of it. I’m hoping it will go back to the way it was before. I do love this medicine."

10 / 10
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  • wat...
  • April 26, 2016

For Weight Loss (Obesity/Overweight) "Started taking Saxenda on April 18th and have had only a few side effects. I have some nausea and a headache in the evenings. I'm hoping this subsides the longer I've been on it. I have lost 6 lbs, which is an amazing accomplishment for me. I have not been able to lose more than 2 lbs no matter what diet I've tried. I get full very fast, only eating about 1/2 of what I used to eat at each meal. Sleeping great, but am experiencing a great deal of fatigue, especially late afternoon and evening. Will continue on and hope this weight loss continues. The doctor gave me a month of samples so I didn't waste money if it didn't agree with me."

7 / 10
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  • Tay...
  • Taken for less than 1 month
  • August 1, 2018

For Weight Loss (Obesity/Overweight) "I've been on Saxenda now for two weeks, and I have lost about 14 pounds. This is also in combination with a low-calorie diet. I have experienced some of the side effects, like nausea and fatigue, but try to take this at dinner time so I am sleeping through most of this. It helps control my hunger and makes me not want to eat as much. Overall, it has been pretty good."

10 / 10
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  • Lak...
  • August 19, 2015

For Weight Loss (Obesity/Overweight) "I've been on Saxenda for 4 weeks after trying unsuccessfully for about 12 months to lose any weight at all. I've lost 6 pounds, which is awesome for me. I just started the 3.0 dose this week, so I haven't even been at full efficacy. The side effects have been mild and tolerable... a little nausea after each bump in dose, some heartburn, and fatigue. They seem to be getting better the longer I am on the medicine. I got a discount card from the Saxenda website that keeps my co-pay at $30."

8 / 10
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More FAQ

  • nig...
  • Taken for 1 to 6 months
  • January 10, 2017

For Weight Loss (Obesity/Overweight) "I have been taking Saxenda for 5 weeks now. I have been titrated from 0.6 for 7 days and increasing every 7 days by 0.6 until I got to 3.0. The nausea and constipation are awful. The fatigue-walking across a room and back makes me feel as if I had run a marathon! Terrible stomach pains and bloating! Yuck. But I will continue taking this as long as the VA will pay for it. I have to lose more weight in order to get my new knees. Does anyone notice if the fatigue and bloating and nausea lessen over time?"

10 / 10
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  • Mar...
  • Taken for less than 1 month
  • January 23, 2019

For Weight Loss (Obesity/Overweight) "Started 3 weeks ago. Immediately dropped to 1200 calories. Side effects include constipation, a funny feeling in my stomach, absolutely devastating fatigue. I didn't think I could make it through the day. It was terrible...my belly fat has not budged and I've only lost 1 kilo! Don't know what's happening to my body. I feel so out of sorts. The last 3 days under 800 cals and still no weight loss, only debilitating fatigue. Reached 1.8 dosage as I wanted it to work so desperately but have to face it...it's killing me! Last dose today, no more. Good luck to you lucky ones that are having great success with it!"

3 / 10
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  • Anonymous
  • Taken for less than 1 month
  • March 20, 2016

For Weight Loss (Obesity/Overweight) "I just started on my 4th week of Saxenda. I lost 7 pounds the first week, but the scales haven't moved since. I'm barely hungry, but am nauseous most of the time with severe heartburn. I did not feel fatigued until the last few days. I'm going to try for 1 more month, hoping the side effects subside."

6 / 10
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  • Zos...
  • Taken for less than 1 month
  • June 12, 2023

For Weight Loss (Obesity/Overweight) "I'm currently in my third week of Saxenda, but it doesn't feel like I've lost any weight. The side effects have been quite bad. I experience nausea and significant indigestion. I find myself eating Tums like crazy, especially at night. I also have a daily headache and an overall feeling of malaise. My energy levels are low, and I could easily sleep all day or stay in bed. If I cough too much, I'm at risk of vomiting. It's hard to say if it's worth it at this point. I'm hopeful that this terrible overall feeling will eventually go away and that my body will adapt, but the lack of weight loss is discouraging. Maybe Saxenda isn't the right drug for me. It's difficult to tell. I still have four pens left, so I'll try to stick with it. Interestingly, I have absolutely no appetite, which makes it even stranger that I don't feel like I've lost any weight. It's frustrating. I was really hoping for better results."

4 / 10
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  • Dir...
  • Taken for less than 1 month
  • October 2, 2018

For Weight Loss (Obesity/Overweight) "Started Saxenda 2 weeks ago. Just upped the dose to 1.8 today. So far, I’m down 14 lbs. I’m mostly experiencing extreme nausea, heartburn, fatigue, and insomnia (which may be causing the fatigue). I was a bit worried about the extreme weight loss in a short time, but reviews here assured me it’s normal. The nausea can be a bit hard to overcome, but I am happy to finally see the scale dropping after years of trying every fad diet out there. I track my calories against exercise and find I typically end a day at 400-500 calories after I factor in exercise."

10 / 10
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  • Kat...
  • Taken for 1 to 6 months
  • September 4, 2018

For Weight Loss (Obesity/Overweight) "Debilitating fatigue, nausea, vomiting. Tried slower titration and cycling up and down to mitigate symptoms. Could not go past 1.8 to 2.4 without unbearable fatigue, nausea, and dizziness that rendered me couch-ridden for two months."

2 / 10
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  • JAG...
  • Taken for 1 to 6 months
  • March 4, 2023

For Weight Loss (Obesity/Overweight) "I’m 47 years old. After four weeks of daily injections, I have lost 14 lbs with minimal side effects. I had burping and heartburn in the first 2 weeks and fatigue lately, but well worth it. Feeling much better overall and pleased with the initial weight loss."

10 / 10
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  • Gre...
  • Taken for less than 1 month
  • June 22, 2017

For Weight Loss (Obesity/Overweight) "I'm wrapping up my first week on Saxenda! My insurance, BCBS, covers it for $50/month with a pre-approval. I'm down 3 pounds! After reading all the reviews here, I was excited to get started but anxious about side effects. After my first dose, I did get fatigued and had to take a nap for 3 hours. But after that one fatigue event, I've only had intermittent, very mild nausea. I've used ginger tea with stevia drops, and that takes care of it right away. But WOW, my appetite is greatly diminished, and I get full faster. I eat about 1/3 to 1/2 of what I used to eat. I walked through our cafe at work today and looked at all the chubby people chowing down on their big lunches and thought... I used to eat like that! So far, so good!"

10 / 10
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  • R73...
  • November 15, 2016

For Weight Loss (Obesity/Overweight) "Saxenda has not helped me at all. It made me super tired and fatigued, bloated, and irritable. I have been taking it now for almost 4 months, didn't lose any weight at all, it did bring my appetite down but almost made my weight stand still. So maybe this medication might be good to help keep you at a desired weight. Now this medication may work for others, but unfortunately, it did not do anything for me."

1 / 10
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  • Suk...
  • Taken for less than 1 month
  • March 28, 2019

For Weight Loss (Obesity/Overweight) "I have used Saxenda for a week, with no side effects whatsoever. Lost 5 lb and was feeling great. Upped my dose to 1.2, and the nausea and fatigue jumped in. Feeling terrible, once feeling okay, will revert to 0.6 dose."

8 / 10
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  • Pha...
  • May 6, 2018

For Weight Loss (Obesity/Overweight) "I am into my 7th week and have lost 14.6 lbs! Started at 230 lb and am at 215.4, an average of 2 lbs per week! (Mod. intensity workout 2x/week) I definitely notice the decrease in appetite and feeling full for many hours after eating (up to 8 hours). Dry mouth is a constant battle for me, fatigue, and on-and-off constipation, but not bad enough to stop. I hope to increase my exercise to 4x/wk to help prevent the plateau I noticed others hit during treatment. It has also helped me make better food choices. I eat a lot of fruits and veggies to help prevent constipation, and it reduces the nauseous feeling if you eat something heavy. I find injecting around noon is best to prevent the late-night munchies for us night owls, but on my workdays, I do it early (7 am), and I definitely notice I feel like eating more that evening. I highly recommend trying this drug to help you get on the right track, but you still need to be willing to adjust diet and lifestyle habits if you want to maintain permanent weight loss."

10 / 10
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  • Jax...
  • February 17, 2016

For Weight Loss (Obesity/Overweight) "I've been on Saxenda since January 11th and have lost 9 lbs. I have a complex medical history, but being lighter and able to do more with my body is the goal. Weight-wise, my goal for the first 6 months is to lose 56 lbs. My side effects thus far have been terrible: extreme nausea, acid reflux, severe fatigue, even some moderate to severe dizziness. I'm not enjoying it much, however, it seems to improve 10 to 12 days after each dose increase. Dosing: because of my side effects, I've needed to slow my dose progression. Every 2 weeks, I increase by 0.6 mg. Insurance: in Canada, the Public Service health care plan covers this medication in some cases. There needs to be a medical need aside from obesity. Good luck, everyone."

9 / 10
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  • tes...
  • April 6, 2017

For Weight Loss (Obesity/Overweight) "I started on this medication on March 6th. To date, I have lost 7 lbs, but I have not gone over the 0.6 dose. I take the injection at night to minimize side effects. I am mostly more thirsty and have some burping and fatigue, but it is manageable. I will take the next level this week and see what it does regarding the side effects. I am keeping to 1350 calories a day when I can, as it is unhealthy to eat under 1200. Mostly vegetables, protein, and carbs. I am also doing 4 hours of exercise a week. This medication is not a wonder drug, as I worry about continued use and the thyroid issue, it is certainly a jump start to make you more aware of what you are eating and the need for exercise. With all this combined, I aim to lose another 55 lbs."

9 / 10
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  • MJa...
  • Taken for 1 to 6 months
  • July 19, 2018

For Weight Loss (Obesity/Overweight) "I've been on Saxenda for 2 months. I lost 10 lbs the first month. I had constipation almost immediately, but started taking a few Citrucel fiber pills daily, and that helped. I was fatigued the first 2 weeks and had mild insomnia. Irritable stomach pain started at the 3 mg dose, but not full-on nausea. More like indigestion, and it's usually when I don't eat. I still have my appetite, but I can't eat a lot at once. I haven't lost any lbs in the second month at all, but I didn't gain the first 10 back either! I did count calories at first using an app. The doctor recommended 1200-1500 for me, but at the checkup yesterday, thought 1000-1200 might work to kickstart more weight loss. I also work out moderately, like walking and step aerobics, 2 times a week. I am going to increase the intensity and go 4-5 times a week now. I'm 38, a woman, 5'2'', and I started at 188 lbs, now 178 lbs. I have 3 months before the next checkup. I am not giving up. I want this to work so I can get off my 5 BP meds."

8 / 10
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  • TCa...
  • Taken for less than 1 month
  • March 12, 2019

For Weight Loss (Obesity/Overweight) "I have PCOS and am trying to lose weight before fertility treatments. I started out at a BMI of 29.7 - 168 lbs, 5 feet 3 inches. I'm down to 160 lbs just 2 weeks later, so an 8 lb loss and counting! The first few days I had a headache, low energy, and got a little dizzy, but that subsided. I barely have an appetite, which makes it easier to switch to healthier foods. I can actually go grocery shopping after work (without starving) and make healthier food choices. I've now incorporated exercise, which has helped the weight loss. Am giving myself 2 months on this prescription because of the out-of-pocket cost and will evaluate from there, but so far I'm happy with the continued progress!"

10 / 10
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  • KKa...
  • April 12, 2018

For Weight Loss (Obesity/Overweight) "I am at week 4. A lot of the side effects have passed, so hang in there if you're still having them. I have lost 11 pounds in 3.5 weeks. So this is working for me so far. Time will tell, as most diets I fall off the wagon after a month. I seldom feel hungry, and when I do, I get full pretty fast. It's not a miracle cure, you do have to have some willpower, because after all, I was emotionally eating before, even when I wasn't hungry. I will be incorporating exercise soon, which I think will help with the fatigue. Everyone reading these, post your experience with this journey, it helps others, including me, to read them, as everyone is different. Not sure why they won't post this, but if they do, to Dietcoke, try to stay away from carbonated drinks, sweets, and alcohol. I find they make the nausea worse. And try to eat six small meals per day, that helped me. Good luck!"

8 / 10
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  • Nan...
  • August 30, 2016

For Weight Loss (Obesity/Overweight) "Lost 8 kilos in the first 4 weeks and then slowly put it all back on over the next three months. Still taking the medication but about to stop because it obviously does not work for me. Chronic side effects of nausea, diarrhea, and extreme fatigue!"

1 / 10
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  • Kim...
  • Taken for less than 1 month
  • May 22, 2018

For Weight Loss (Obesity/Overweight) "I'm only on day 5 of Saxenda. Firstly, I have been working out and calorie counting but have been at a weight-in standstill. I'm trying this to get an extra push. I'm 5'7", starting weight 370 lbs. Working out and calorie counting got me to 334 lbs. Saxenda day 5, I'm 229 lbs. Fatigue is bad. I'm starting to get a very sore throat, more on the right side and pain when swallowing. (I'll update more). Not hungry, no constipation... I do drink water. Hoping the tiredness goes away... I loved working out and now I just want to sleep."

8 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.