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Lactulose and Pain: What Users Say

Brand names: Enulose, Kristalose Generlac Constilac Cholac

Pain: mentioned by 12 users (7.8%)

Based on user experiences from 153 Lactulose reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

gas 26.1%
bloating 11.8%
cramps 11.1%
diarrhea 7.8%
nausea 7.8%
pain 7.8%
constipation 5.9%
upset stomach 2.0%
vomiting 2.0%
water retention 2.0%

Reviews for Lactulose

Commonly mentioned side effects
  • CKR...
  • Taken for less than 1 month
  • March 18, 2014

Lactulose for Constipation, Chronic "This was the only treatment that worked after my hemorrhoidectomy - had to go to the ER to get this prescription though after three days of constipation from the pain meds - too bad my surgeon did not prescribe this to me earlier."

9 / 10
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118 Report
  • Jus...
  • October 27, 2013

For Constipation, Chronic "This is a miracle. Taking Oxycodone makes you so constipated, it's not funny. I take 80ml-100ml, which is a dose I wouldn't recommend to someone taking it for the first time. Start small and see how it works for you. I take it right before bed. And by the time I wake up, it's toilet time, every time. Sometimes I will get a slight pain in my stomach during sleeping and it can't wait till my usual wake-up time."

10 / 10
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108 Report
  • jus...
  • Taken for less than 1 month
  • September 17, 2015

For Constipation, Acute "Helps you a whole lot! Except you could get sore on the underside and stay extremely close to the toilet."

9 / 10
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23 Report

Frequently asked questions

  • kmv...
  • Taken for less than 1 month
  • July 2, 2020

For Constipation, Chronic "Doctor prescribed 15 ml 2x/day. Started today at 10:50; I had a normal BM at 2:30, first after many years. Then I took it again at 5:00; no luck. I have multiple sclerosis since 2005 and IBS-C. This took away my pain one time, and I hope it does in the future."

10 / 10
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19 Report
  • Ver...
  • December 5, 2017

For Constipation, Acute "This worked after 48 hours. The label said that it could take up to 48 hours, but most of the other reviews said that it worked much faster, so when it didn't work quickly for me, I began to lose hope. Thankfully, it worked, pretty much exactly after 48 hours. I'm in my second trimester, and hadn't done a poo for 4 days, and the last time had been very painful. I'd felt incredibly bloated and uncomfortable, and hunched over when I walked, and couldn't get comfortable to sleep. When I first went again after 48 hours, it wasn't easy, but it wasn't really painful either. I stirred the medicine into large glasses of water to help me drink enough fluids, and also to dilute the excessively sweet taste."

7 / 10
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16 Report

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  • Shi...
  • Taken for less than 1 month
  • February 15, 2018

For Constipation, Acute "I had constipation as a side effect of the Codamol I was taking. I was sore, and I’m a big dude. My stomach was solid all the way to the bottom of my ribs. I drank two mouthfuls of this stuff and had the best clear-out ever, must have been an hour on the loo over a three-hour period."

9 / 10
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18 Report
  • Luc...
  • June 12, 2021

For Constipation, Acute "4 days of suffering, nothing was coming out of me despite 30 times of trying, also had a lot of pain at my kidneys. I had all the fiber foods, drank gallons of water, but nothing!! One of my friends suggested loose syrup, which I drank 40ml. Finally, I felt some pressure, took my chance, but the size of the tool was so wide that my body was undersized. What came next is graphic, but I literally had no choice. I had to manually clear some of the hard stool out of my butt. Passage still felt super small for the huge train, but I had to push it so hard, it felt like I was giving birth as it exited me. What followed the impacted stool was runnier, and everything was just free-flowing. This is a super painful experience, and I now understand what others go through. If my experience could be of any help, the medicine is for sure effective, but it took 8+ hours to show results with a lot of my own efforts to make it work."

9 / 10
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14 Report
  • Luc...
  • June 12, 2021

For Constipation, Acute "4 days of suffering, nothing was coming out of me despite 30 times of trying, also had a lot of pain at my kidneys. I had all the fiber foods, drank gallons of water, but nothing!! One of my friends suggested loose syrup, which I drank 40ml. Finally, I felt some pressure, took my chance, but the size of the tool was so wide that my body was undersized. What came next is graphic, but I literally had no choice. I had to manually clear some of the hard stool out of my butt. Passage still felt super small for the huge train, but I had to push it so hard, it felt like I was giving birth as it exited me. What followed the impacted stool was runnier, and everything was just free-flowing. This is a super painful experience, and I now understand what others go through. If my experience could be of any help, the medicine is for sure effective, but it took 8+ hours to show results with a lot of my own efforts to make it work."

9 / 10
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14 Report
  • Ayl...
  • October 10, 2021

For Constipation, Acute "I suffer from endometriosis, and for the past 5 years, I've been prescribed codeine on and off when I have my flare-ups, which are roughly only 4-6 times a year. I'd always been prescribed laxatives that weren't very helpful with my constipation - they either took too long to work, and I'd be in pain for a few days, or they didn't soften the stool enough, so when I did finally pass a motion, it would be extremely painful. I discovered lactulose 5 months ago when my mum bought me some from a pharmacy, and it has been a lifesaver! I only take it when I haven't passed a motion in a few days, and every other home remedy I do (kiwifruit and prune juice, increased water, exercise) hasn't helped. It works within 1-2 hours, and it softens the stool enough so that I feel like I'm passing a normal motion, and it's virtually painless. I highly recommend this! It's the best laxative I've ever come across, and I've had my fair share of trials of different laxatives in the last 5 years."

10 / 10
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11 Report
  • Eva...
  • Taken for less than 1 month
  • March 31, 2023

For Constipation, Chronic "After a colonoscopy, I was prescribed lactulose 10 ml. I have IBS, and the colonoscopist didn’t even ask if I have IBS. Within half an hour, I was in a bad way - diarrhea, feeling sick, then after that, I got spasms and muscle cramps in my foot. I’m pretty sure that was a side effect of the medication. This lasted through the night until the next day. Most of the symptoms went away, except the foot muscle cramps, and my whole foot is sore, numb, and tingling. I’m pretty sure it is a severe electrolyte imbalance that can cause serious health problems, such as muscle spasms, twitching, a seizure, or a fit. Yes, it’s awful, and I’ve been to the doctor, and they don’t do anything. Apparently, lactulose shouldn’t have been given to me if I am an IBS sufferer. I just hope this pain goes away. Painkillers don’t even help. I will never touch this stuff again."

1 / 10
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5 Report
  • Joy...
  • Taken for less than 1 month
  • July 17, 2021

For Constipation, Chronic "I would never take this again. My naturopath prescribed it...so I figured it would be good. I got nausea, terrible abdominal cramps for hours! And I had trouble passing stools. And rectal pain and swelling! Stay away from this drug...side effects all next day!"

1 / 10
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6 Report
  • Kim...
  • Taken for less than 1 month
  • June 10, 2023

For Constipation, Acute "After 30 ml (2 doses), I had horrible bloating, gas, pain, nausea, and an unwell feeling. Had to discontinue use."

1 / 10
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4 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.