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User Reviews for Armodafinil to treat Depression

Also known as: Nuvigil

Armodafinil has an average rating of 7.9 out of 10 from a total of 29 ratings for the treatment of Depression. 72% of reviewers reported a positive effect, while 17% reported a negative effect.

Armodafinil Rating Summary

7.9/10 average rating

29 ratings from 31 user reviews.

Compare all 189 medications used in the treatment of Depression.

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Reviews for Armodafinil

.hope · Taken for 2 to 5 years November 2, 2020

“After 25 years of treatment resistant depression, Nuvigil relieved my symptoms in less than 1 hour. Peace of mind, contentment and the ability to enjoy life again. And no side effects. But can’t find a psychiatrist who will work with me on higher dosage. Afraid of losing their licence. I think they should lose it for not treating me with the only thing that has ever worked, including ECT, TMS and ketamine. When will the medical community learn to listen to patients like me?”

10 / 10
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r-m-c · Taken for 2 to 5 years February 4, 2021

“I tried ECT, ketamine, and every medication and combination of medications known to man for 24 years. I was been hospitalized 6 times for depression. Since starting on Armodafinil in December 2018, I have had a life again. It has quite literally saved my life. I am productive, empowered and happy again. I could literally cry at any moment just to think about this.”

10 / 10
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dianemob July 13, 2019

“I've had severe treatment resistant depression for 25 years. I tried meds, ect, tms but nothing worked. 3 years ago I was taking 4 prozac, and 2 lamictal and I was still extremely depressed. 3 years ago my doctor decided to try Nuvigil. It saved my life. And also gave me my life back. Within 1 hour after the first dose I was back to normal. I started being more social, finding hobbies, and most important of all - I had peace of mind. ”

10 / 10
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Susan · Taken for 10 years or more October 7, 2020

“I have taken Armodinil before this was Nuvagil. I have major depression. I also take Trentillix. ARMODINIL HELPS ME GREATLY. IT DOES HELP PEOPLE WITH DEPRESSION. I DO NOT CARE WHAT doctors and chemist say.”

10 / 10
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BurtBurt April 9, 2013

Nuvigil (armodafinil): “Provigil then Nuvigil (slightly less expensive) helped save my life. Took Provigil first, switched to Nuvigil (same effect), for 6.5 years now. Day one value, no side effects as far as I know. Still same dose (250mg Nuvigil, equivalent of 200mg Provigil), never increased or decreased. Effect same today as day one. Note: I've been on a "cocktail": 20mg Lexapro and 1mg Klonopin daily, plus daily mindfulness meditation and weekly CBT. But 6.5 years of lovely life after 3 terrible episodes of major depression in under 6 years. Certainly have ups and downs, but not severe and brief. If I run out for a few days I'm grumpier, less resilient but Nuvigil greatly clarifies my thinking and energizes me. It's not for all, but miracle for me.”

10 / 10
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Didee · Taken for 1 to 2 years March 13, 2018

“I have suffered from treatment resistant. severe, chronic depression for 25 years. Tried all meds wchich either didn't work or quit working, or side effects were not tolerable. I've had ECT and TMS also. About a year and a half ago my doctor prescribed Nuvigil. It saved my life! No side effects, works within an hour. It does wear off in the evening and sometimes I become depressed but I know that the next day I will be OK, unlike the endless hopelessness of depression without Nuvigil. I can't understand why none of the drug companies will conduct tests and use it to help more people in my situation.”

10 / 10
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Susan · Taken for 6 months to 1 year April 29, 2021

“Have suffered with depression most of my adult life. Diagnosed with MS age 1985 -26 yrs ago! With age & MS - anxiety, major fatigue, major depression & cognitive dysfunction - all were making it difficult to get out of bed, much less function effectively. Psychiatrist of many years prescribed Nuvigil 10 yrs ago - and it has been a LIFESAVER! On days that I have to make decisions, socialize and get anything “normal”, such as housework done - I will take (2)250mg NUVIGIL/armandofanil - early am, mid afternoon. But as others have mentioned, I will also stop taking it when it begins to losing it effectiveness for 3 days or so. And during those 3 days, I am USELESS. I also take Seroquel & Lamictal as antidepressants - and Xanax for anxiety.”

10 / 10
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Melancthon November 26, 2010

Nuvigil (armodafinil): “I have suffered from clinical depression for years. I barely have enough energy to get out of bed. My house is a mess and so am I. My MD put me on 75 mg of Nuvigil and the effects were amazing and instant. The only side effect I had was a mild headache and sleeplessness which both went away after a few days. I am gradually getting more energy and feeling more optimistic. I can see why the Caphalon is investigating this drug for treatment of depression by the FDA. My biggest problem is the cost, as I have no insurance. I can't pay 1/3 of my income each month for a pill. I qualify for the patient assistance program, so will try that. Otherwise I don't know what to do, as the MD has only given me perhaps a month of samples.”

9 / 10
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Onnie Rose April 4, 2013

Nuvigil (armodafinil): “I found Nuvigal to bring my life back from depression. Before Nuvigal I couldn't keep my eyes open and live my normal life with 3 boys! Now, after Nuvigal I can actually play with my kids and be a normal mother. I don't know where I would be without it. It really turned my life around for the best!”

10 / 10
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Commoner · Taken for 1 to 2 years May 2, 2021

“Armodafinil works for me after everything under the sun including ketamine and TMS. If I miss a dose, I’m hurting, so it’s got to be used consistently to work for me. If I take it too late in the day it has a tendency to contribute to insomnia. However, it boosts me out of the doldrums as quickly as ketamine is supposed to in effect. Combined with Abilify it’s not too stimulating like caffeine. Without Abilify, some tension, jitteriness and perspiration is possible. Abilify helps calm anxiety. So the combination works reasonably well for me.”

9 / 10
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FLUFFHEAD November 20, 2016

“Nuvigil has given me myself and my life back and I am so grateful! My doc first gave it to me about 7 years ago. The script was for 5-10 days. Tried it again a few years later after a bad episode and again for 5-10 days. It was like a magical pill that within 1 day snapped me out of a rough episode! Fast forward to this past April or May, probably my worst depressive episode ever started in March. Anyway, started back on nuvigil as an ongoing med. NOTHING! Ran out and couldn't get to my doc so I ran out. So glad I did bc I got back on it Thursday night and I was feeling better Friday! I do take other antidepressants so I don't know how this works on its own. I never post here but had to in hopes that my story will help someone!”

10 / 10
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davetrindle November 27, 2016

“Immediate lifting of depression; gave me my life back. Best to take 1/2 of 250mg very early on empty stomach with lots of water. I find it best taken around 5 am, go back to bed and wake later feeling great. Take another half before noon if needed, but, again, have an empty stomach and big glass of water. After a week or so, effects not as strong and can make you feel paradoxically very tired. Take 2-3 days off, and it will resume working. Be cautious and mindful of how your personality may be affected; reduce dosage if you're getting "too happy" overly friendly and too talkative. Also, it really focuses you and its good to make an effort to "break" the hyperconcentration by taking a break, a walk outside, hot shower. I've been taking 4 yrs”

10 / 10
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Mirsad September 3, 2021

“Long time sufferer from depression.I’ve had high hopes after reading all the positive reviews about armodafinil.I finally got some samples and took 75 msg artvigil .It worked within half hour but my anxiety was through the roof on the verge of panic attacks. I drank lot of water but anxiety just kept getting worse .I felt jittery and anxious all day in to the night. 2 days later I got a terrible headache and anxiety still present. I take mirtazapine on night time and usually within half hour of taking mirtazapine I would feel sedated and sleepy. This time nothing, I was still wide awake until the early hours in the morning with persistent anxiety/panic attacks .Now 2 days later still feel the effect of armodafinil, anxiety , spaced out and general bad feeling. I might try a lower dose again in a couple of weeks to see if it works better but not holding high hopes .Really disappointed as this was one of my last resort to get my depression In order .”

2 / 10
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Flat without · Taken for 1 to 2 years September 27, 2019

“My boy died and I was devastated. My psychiatrist had given me Provigil to help me when my mother passed away. Now, I am completely alone. I took Nuvigil in order to meet with his widow and plan his funeral. I was able to concentrate to get through it. That was over three years ago. Now I take it when I know there is something I have to do. When the grief overwhelms me I take the Nuvigil. 50 or whatever the low dose is. I am better off when I take it, makes me feel like my old self again.”

10 / 10
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Callie1217 May 10, 2017

“I've taken nuvigil off and on for about a year, along with 20mg lexapro. I take it as needed for depression and daytime sleepiness (I was falling asleep while driving). I find that it makes me agitated and irritable if I take it every day, so I only take 150mg when my depression is causing extreme lethargy and lack of motivation. When I do take it, it usually works within an hour. I am motivated, focused, and productive on this medication. It even helps with my social anxiety, and I find that I'm more cheery and outgoing. I'm more talkative too, but in a good way - not in a manic way. The problem? It wears off after 6-8 hours, sometimes leaving me with a headache. Overall, however, it has been a big help to me!”

8 / 10
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Dave T · Taken for 10 years or more January 2, 2020

“armodafinil is a miracle drug for me. I take it in addition to Lexapro and Klonipin. However, it only works for a few days, then I have to take a few days off. I'm still giving it a 10 because a few days relief at a time is still a miracle. Start low and adjust dosage slowly, because higher dosages can make you hyper. My daily dosage is 1/2 of a 250mg Note: I know Nuvigil hasn't been around 10 years, but before Nuvigil I took Provigil, and it worked well too”

10 / 10
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not a fan January 7, 2012

Nuvigil (armodafinil): “Be careful of medically induced hypo mania. I took this for years. Helped with depression and I decided to put up with increased anxiety and racing thoughts. Without my realizing it, I became extremely manic and caused irrational and destructive behavior. Thank God, switched doctors and medicines (to Lamictal). I wish I had known this can induce manic behavior! Please be careful because mania lies to you and makes you think all is well.”

1 / 10
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Anonymous December 11, 2011

Nuvigil (armodafinil): “150 mg NuVigil does work somewhat for my depression, but the primary effects wear off after a few hours and I feel more tired than usual. It is better than any SSRI, SNRI, MAOI, atypical, or tricyclic antidepressant that I have taken.”

7 / 10
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Lifelong depression struggle · Taken for 6 months to 1 year May 21, 2017

“I take Seroquel XR, it helps with the depression but makes me tired. I am taking 250mg Nuvigil to give me a bit of energy. It seems to take two hours to really hit, then I get a rush of anxiety. That last for about ninety minutes. It smooths out about 3 and a half hours in. Then at 5 hours there is a drop-off. I get lethargic and a bit down for an hour or so, then the evening is largely the best period. It does seem to help, but it also hurts. I don't know. I never do.”

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mdd123 August 15, 2011

Nuvigil (armodafinil): “Started at 150 mg, took half a day and felt like a new person - it changed my life. Quickly found I need to take the full tablet to get the same effect. Three months ago doctor increased to 250 mg, take full tablet but the effect only lasts 3-4 hours. Your body becomes immune and needs more and more. And now I "crash" early afternoon and become very depressed. Took appetite away, lost 20 lbs in little over a year.”

6 / 10
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MrUbiquitous July 12, 2011

Nuvigil (armodafinil): “I have used Provigil and now am on Nuvigil that helps for various issues. I realized I may have an attention problem when I took Provigil for the first time and scored 10-30 points higher than I ever have on a Vocational Rehab. IQ test. For those of you who are low income, there is a foundation called Cephalon Cares that gives me my medication for free. You have to be under a certain income level but it saves me much money since I do not have insurance either.”

8 / 10
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W-guest August 26, 2011

Nuvigil (armodafinil): “My psychiatrist initially prescribed Nuvigil to enable me to be alert and awake during the day. I suffer from bad insomnia and I'm being treated for major depressive disorder and post traumatic stress disorder. I'd taken Provigil in the past and it seemed to help with depression. Yesterday I overslept and decided not to take my Provigil fearing it would keep me awake even longer than usual. That was a huge mistake, I became horribly, morbidly, depressed. I didn't make that mistake this morning, I took my Nuvigil as usual and my (worse than usual) depression is gone. I haven't experienced any side effects but I wish Nuvigil would enable me to lose weight like it does many people. I was on Abilify for a few months and gained several lbs.”

10 / 10
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JennyLynn4eva November 14, 2011

Nuvigil (armodafinil): “I started taking 150mg of Nuvigil with my Staterra. My doctor wanted to wait and see if the Nuvigil worked before discounting Stratterra. Well the first 4 days of Nuvigil at 150mg worked well my doctor decided to up it to 250 mg and now it no longer works at all and in fact I feel very nauseous after I take it. I am so very disappointed!”

1 / 10
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Helpless until well · Taken for 2 to 5 years February 23, 2019

“I have Depression. The reason for sadness that includes several other conditions. Acute stress disorder, anxiety etc. May not work for you. Need a psychiatrist to get as much medicine as I do. I take Nuvigil brand name 250 mg 3 times a day, with Viibryd 20 mg 3 times a day and Enlyte (red soft capsule) 3 times a day. They have saved my life. Without these my life was miserable. I pray one day I won’t need it. I aged and then was in ICU after an operation. Life changed for me after that. Insurance won’t cover Enylte yet. I get it from the Enlyte company without a prescription cost me $150.00 a month. Need a prescription at pharmacy for it.”

10 / 10
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Anonymous November 7, 2011

Nuvigil (armodafinil): “This medicine is the only one to help me in my depression.”

10 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.