Skip to Content

User Reviews for Armodafinil to treat Chronic Fatigue Syndrome

Also known as: Nuvigil

Armodafinil has an average rating of 7.3 out of 10 from a total of 37 ratings for the treatment of Chronic Fatigue Syndrome. 65% of reviewers reported a positive effect, while 14% reported a negative effect.

Armodafinil Rating Summary

7.3/10 average rating

37 ratings from 39 user reviews.

Compare all 5 medications used in the treatment of Chronic Fatigue Syndrome.

10
11%
9
32%
8
22%
7
11%
6
5%
5
3%
4
3%
3
3%
2
5%
1
5%

Reviews for Armodafinil

Anonymous February 27, 2010

Nuvigil (armodafinil): “I began suffering from Chronic Fatigue Syndrome about a year ago. Didn't know I had it, just knew I was sleeping more than I was awake. Just diagnosed in January and have been taking Nuvigil since then. Started at 150 mg a day, but it wore off by mid afternoon. Have since increased the dosage to two pills a day. I take the second pill in the afternoon and it keeps me going for another 6 hours or so. I haven't had to take a nap since I started taking the medication and I am able to concentrate more. I feel more alert and can get much more accomplished during the day. I don't have trouble sleeping or staying asleep. This medication has been a miracle that has given me back my life.”

8 / 10
Was this helpful?YesNo
Watsonsrus8 August 5, 2013

Nuvigil (armodafinil): “I have been on Nuvigil for about one year. I have fibromyalgia and Chronic Fatigue Syndrome. Before Nuvigil I couldn't stay awake. When I would have my morning coffee I would be fighting sleep. Although I am still very tired and weak I can stay awake for the entire day now. I feel this is the most important medicine I take. It works for both CFS and Fibromyalgia.”

Was this helpful?YesNo
vr_tired July 6, 2009

Nuvigil (armodafinil): “Got a trial prescription for Nuvigil 150mg tablets, first day was incredible, but after a few days the effectiveness was greatly diminished. Still worked but did not have the same effect as day one. Worried about using it regularly since it is not covered by insurance and without that the cost is outrageous ($330/30 tablets). Does not leave you nervous like Ritalin, and lasts longer than Provigil. Worth trying if your health care plan covers it.”

9 / 10
Was this helpful?YesNo
Biggersnook · Taken for 1 to 6 months March 8, 2013

Nuvigil (armodafinil): “I have had 4 back surgeries ( pins, screws, plates, etc.) and both of my hips replaced, all before turning 43. Before this, I earned a Ph.D., became a Prof. in Accounting was rewarded multitudes of student-awarded, colleague-awarded, and superiors-rewarded accollades. Then, with all the narcotics, opiods, hospitalizations, etc, tenure was literally jerked from my grasp, and I have been forced out of three other universities since. The depression of repeated recoveries from surgery and then med withdrawals and job losses drove me into extreme depression. Got the pain under control but it got to where I was in bed 6 of 7 days full-time. I was taking Cymbalta, but when my Dr. tried Nuvigil, it brought me back to the happiness I had known before.”

10 / 10
Was this helpful?YesNo
fibromyalgia October 23, 2009

Nuvigil (armodafinil): “So far I love Nuvigil. I can actually go all day without needing to lay down in the afternoon. I suffer from Fibromyalgia and Chronic Fatigue. I may need to bump it up as 150 mgs. does not seem to make me as awake as it did the first week. I like the way it makes me feel awake but not nervous and jittery like Ritalin did. I can now work a shift and actually come home and do chores around the house instead of lay down. I have had no side effects so far and have been on it a month.”

8 / 10
Was this helpful?YesNo
Cat · Taken for 6 months to 1 year August 17, 2019

“I have had CFS (chronic fatigue syndrome) for many years undiagnosed until recently. I was almost bedridden, had to miss lots of days at work and thought that I would have to file disability. My dr. Prescribed Nuvigil 50 mg. I have not missed any work due to illness . It has gave me my life back. Praise God for it.”

9 / 10
Was this helpful?YesNo
Anonymous November 19, 2010

Nuvigil (armodafinil): “I have Chronic Fatigue Syndrome and was prescribed Provigil, insurance denied coverage. Doctor then gave me samples of Nuvigil 150mg. WOW! what a difference, first couple of days a few heart racing minutes but then after that, it was great. Ran out so asked doctor to order at pharmacy, insurance denied again. When I take Nuvigil I can work all day and sleep just fine at night, instead of taking a 3 hour nap after school and then back to bed at 8PM. I have so much energy, I take it at lunch time, this way it won't wear off too soon. I have skipped days to make samples last and there is definitely a difference in my quality of life. Actually I HAVE A LIFE when I take Nuvigil.”

9 / 10
Was this helpful?YesNo
Anonymous July 17, 2011

Nuvigil (armodafinil): “I have struggled significantly with fibromyalgia and chronic fatigue syndrome since 2007. I am mid 30s. The CFS is much more debilitating than the fibromyalgia. Nuvigil has been the only treatment making a significant difference. I can now function much more than 3 hours a day. Nuvigil is changing my life.”

10 / 10
Was this helpful?YesNo
ishe2she November 17, 2009

Nuvigil (armodafinil): “I am on Nuvigil now and have been for several months. I take the 250mg tabs. Before Nuvigil, I took Provigil for over a year and my doctor told me that Nuvigil was a new refined version of Provigil. They work great for a while, then your body gets used to it; I will go a day or two without it and it seems to work better that way. My insurance did not want to pay for Provigil, so my doctor wrote a letter that it was imperative for my quality of life, so they started paying. When I switched to Nuvigil, nothing was ever said about it. It does make me more alert, but I can still lay down and take a nap while taking it. It is sure better than nothing, Or I would be in bed 24/7 as before.”

6 / 10
Was this helpful?YesNo
Jennisonjr February 27, 2012

Nuvigil (armodafinil): “I had to fight with insurance to cover my Nuvigil but finally got them too. I have battled to get my hypothyroidism optimized for years and even when I had it at a pretty good level, I was always tired. The Doc labeled it chronic fatigue and the Nuvigil has made a hug difference. I feel like I can finally keep up with everybody else and don't have to stand up at the back of meetings at work to stay awake. Nuvigil did have some strong side effects at first (headache, nauseous, lack of appetite) but they were pretty much gone after a week or so.”

8 / 10
Was this helpful?YesNo
Anonymous May 10, 2010

Nuvigil (armodafinil): “Have been on Nuvigil 150 for about a week for MS related fatigue. It gives me energy to stay awake but after 7 or 8 in the evening, I am beat. Only problem is I don't sleep well and my appetite is nonexistent.”

7 / 10
Was this helpful?YesNo
College Prof May 6, 2010

Nuvigil (armodafinil): “I suffer from SAD and dealing with people and students (yes, I understand the irony of the career choice) on a daily basis leaves me burned out most days from the stress of teaching to 300 students and dealing with people, in general, but a simple combination of Xanax (0.25 mg) before a class and daily Nuvigil (75 mg) completely erased the problem. I work all day, I'm calm and focused in classes, and with a Xanax (0.5mg) before bed I sleep a full night without problems.”

9 / 10
Was this helpful?YesNo
Anon · Taken for 1 to 6 months April 17, 2019

“CHRONIC chronic fatigue sufferer here. Have been taking Adderal for years with mixed results. Was very hopeful for this medication but it did absolutely nothing for my mental or physical tsate. If anything I would say it had the opposite effect and put me to sleep. Extremely frustrated and disappointed.”

1 / 10
Was this helpful?YesNo
Anonymous May 15, 2011

Nuvigil (armodafinil): “I have had chronic fatigue syndrome for over 20 years and it controlled and stole my life. Nuvigil has given it back to me. Prior to Nuvigil, I would collapse at around 1 pm and have to sleep around 2-3 hours, then I would have to go to bed by 9 every night. Now I am living an almost normal life. I don't need naps and go to bed at 9-10pm and find that my mental alertness is greatly increased (i.e. it seems to counteract "figrofog"). Drawbacks are increased blood pressure and insurance won't cover it.”

9 / 10
Was this helpful?YesNo
sourpuss_ashkenazi · Taken for 6 months to 1 year August 16, 2015

“Pros: turn into a hardworking genius legend in the day time after taking a pill at 7:30am. Turn sociable and enjoy chatting with people for the sake of it. Cons: some suspicious side effects. diarrhea (it's manageable) and very frequent urination. Hunger massively suppressed (you might consider this a good thing), occasional headaches, can make you aggressive when you arent at all normally. If you're a person who has trouble sleeping this will keep you up far later. And also there is a slight psychedelic element to this drug as it peaks, you sometimes get weird feelings and thoughts you know could never happen normally off the drug. It's still less bad for you than cocaine or something so that's how I rationalise it.”

8 / 10
Was this helpful?YesNo
Anonymous October 29, 2011

Nuvigil (armodafinil): “Nuvigil works so well that I am now able to function in most aspects of my day. Before Nuvigil, I was hardly able to perform activities of daily living. Now, I am able to do grocery shopping, run errands, etc. I am much, much more alert. I had tried Ritalin before Nuvigil and Ritalin made me a nervous wreck whereas Nuvigil is easy and without the shaking. The cost of Nuvigil is outrageous. ”

9 / 10
Was this helpful?YesNo
Rockyyy93 February 26, 2014

“Lupus: I've been on Nuvigil for about a year now. I have a mild form of Lupus and the medicine I take for that does more harm than good. So we just decided to treat my painfully low energy level with Nuvigil. It has changed my life. When I first started it I had mild head aches and was sensitive to light. But once I was used to it I regained my quality of life. I was able to enjoy mornings and not count the hours before I could return to sleep. The best part is I can take it as needed now. Highly recommend.”

10 / 10
Was this helpful?YesNo
Xyzsxz · Taken for 1 to 6 months February 23, 2020

“I have been taking this drug for about 2 months without any significant improvement with my "always feeling drowsy" as well as chronic fatigue syndrome. I started with 150mg a day and my dose has increased Although it keeps me awake, but does not much help with my "feeling of lethargy and fatigue" I can suggest this medicine to those who only suffers from excessive drowsiness or daytime sleeping. Others may want to find different substitutes eg. methylphenidate. Note that I was prescribed with armodafinil by a professional psychiatrist and I do not advise or promote anyone to self medicate based on my experience.”

6 / 10
Was this helpful?YesNo
Anonymous June 7, 2011

Nuvigil (armodafinil): “Since starting on Nuvigil, I have yet to take my afternoon nap. I take Nuvigil each afternoon around 12:30 which will last until 9 pm, right when I'm about to hit the bed. Works like a magic. But I still need something to give me extra boost. However, I feel 90% recovery. It also helps with concentration but not much. Does make you feel good.”

9 / 10
Was this helpful?YesNo
cor1nna December 23, 2011

Nuvigil (armodafinil): “Started taking this for extreme tiredness a week ago after my exhaustion level rose to unacceptable levels. In previous Multiple Sclerosis episodes I had been on Provigil, but stopped taking it due to severe headaches, and found I didn't need them anymore anyway. So far I haven't had any headaches and my mental alertness is significantly higher. My physical energy is still low, but has improved some. I can make it through a quick shopping trip without having to sit down and rest. I'm hoping that continued use of the medicine will build up my endurance level over time.”

7 / 10
Was this helpful?YesNo
Anonymous November 7, 2011

Nuvigil (armodafinil): “In my opinion, there are a lot of pros and cons for this medication. I took it for a while with no ill effect, but something must have changed, and it made me feel extremely ill (dizziness, heart palpitations, nausea, headache.) I stopped taking it because of this and definitely noticed a difference. I think that taking a half a pill every few hours has eliminated my problems with the medication and works to keep me awake and focused for longer.”

8 / 10
Was this helpful?YesNo
Nuvigil or Crash January 17, 2010

Nuvigil (armodafinil): “I have been on Nuvigil for about year and although my body is used to it, it still works and is crucial for my quality of life. I have had numerous surgeries on my spine, plus a lot of my tendons have torn (both rotator cuffs) plus both my Achilles have tiny ruptures, leaving knots on the back of my heels. My body is falling apart, but at least the Nuvigil keeps me at a pace I can handle. Two weeks ago my insurance failed to pay and my doctor gave me sample of 150mg (I had been on 250mg before). Now I am out of it all and I have crashed. My nurse called and said that it had been approved for 6 more months, so I actually get to pick it up tomorrow. Maybe I will be able to get out of the bed now and get things done.”

9 / 10
Was this helpful?YesNo
Mojohinton November 23, 2016

“I have had HIV/AIDS for over 30 years. Needless to say that chronic fatigue has always been one of my biggest obstacles. I found this drug through an interview done by Diane Sawyer a few years back (referred to as its original name Provigil). I started Nuvigil/Armodafinil 200 mg soon after. My world went from black & white to living color. I was even able to have a late afternoon lie down for 30 minutes to an hour and wake up feeling great again. No feelings of speediness or anxiety. At first I started with the Armodafinil 200 mg but then went down to 150 mg because I did notice a slight tendency to a bit more aggressive later in the day or early evening after a few months use. After going down to 150mg it evened out and felt great.”

9 / 10
Was this helpful?YesNo
Anonymous January 16, 2010

Nuvigil (armodafinil): “I never have side effects from medicines so I foolishly took Nuvigil without reading the literature. Couldn't figure out where the headaches, fever and general feeling of 'being sick' came from. Palpitations, the tingling in extremities, feeling as though my mind was always two steps ahead of my reactions...just too much. I feel fortunate nothing worse happened.”

2 / 10
Was this helpful?YesNo
Anonymous RN October 10, 2011

Nuvigil (armodafinil): “I have a very rare autoimmune neuromuscular disorder that causes many symptoms, including weakness. I find that taking Nuvigil 150mg daily helps me with having a little bit of more energy and also improves my mood. My cravings for carbs has decreased, which is good as I now eat foods that are better for me. Luckily, my insurance has paid for it.”

8 / 10
Was this helpful?YesNo

This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.

Learn more about Chronic Fatigue Syndrome

IBM Watson Micromedex

Symptoms and treatments

Mayo Clinic Reference