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Abemaciclib for Breast Cancer User Reviews (Page 2)

Brand names: Verzenio

Reviews for Abemaciclib

Commonly mentioned side effects
  • Hil...
  • Taken for 1 to 6 months
  • June 5, 2023

"I was prescribed 150 mg twice a day because I am at high risk of recurring lobular breast cancer. After 5 weeks, I could no longer tolerate it due to diarrhea, fatigue, weight loss, and many other side effects. I was given a 4-week break to recover and restarted on 50 mg twice a day. I have been taking the low dose for 6 weeks, and I am tolerating it very well. The intention is to increase the amount again gradually, and I hope I can cope with it because I am concerned that just 50 mg twice daily will not be very effective."

9 / 10
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8 Report
  • Vio...
  • Taken for 1 to 2 years
  • February 4, 2024

"Side effects (Over 1 year and the below continues constantly): Fatigue, decreased energy, hair thinning, upset stomach, bloating, body ache, hand numbness and tingling, increased weight, decreased appetite, blurred vision, diarrhea, upper right abdomen inflammation, mental fog."

8 / 10
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5 Report
  • Ano...
  • Taken for 1 to 2 years
  • May 22, 2025

"Diarrhea, fatigue, decreased stamina, muscle aches, and watery eyes, which I find very annoying and embarrassing. I can end up with crusted salt marks on my face. Hair thinning, lower immunity, and raised LFTs, neutropenia. The diarrhea causes anxiety when out, as I enjoy walking and cycling, so often no toilets around. I am taking adjuvant abemaciclib and on cycle 21, but still taking 150 mg twice daily."

5 / 10
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Frequently asked questions

  • Ano...
  • Taken for 1 to 2 years
  • June 24, 2025

Abemaciclib "I have been taking this for 18 months of the 2 years I am supposed to take it but am thinking of asking the consultant if I can come off it. I suffered initially with severe diarrhea but not for too long, however, the initial dose of 100 mg twice daily gave me excruciating lower abdomen pain, so this was dropped back to 50 mg twice daily and that dose suited me. As my infection resistance has, I believe, diminished over the months last year, I repeatedly had UTIs which, in the end, the GP put me on a preventative dose of Trimethoprim 100 mg daily. 10 months down the line, this is now not holding back the infection, which is why, amongst other things which are getting worse, I will be having the discussion with my consultant. Other side effects are now blood in my urine (which could be the long-term antibiotics), I am much more tired and have more bad days than good, aches in my hips and legs, sore gums, and sometimes no appetite at all."

8 / 10
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  • Tuc...
  • Taken for 1 to 2 years
  • September 20, 2020

Abemaciclib "I have been on Verzenio for 14 months. After 2 months, it shrank my tumor by 60%, and after 12 months, bone mets were almost gone. A 12-month PET scan showed no active cancer cells."

10 / 10
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59 Report

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  • Luc...
  • Taken for 6 months to 1 year
  • February 19, 2020

Abemaciclib "Verzenio has worked after my wife’s initial treatment failed and her cancer returned. She had some initial diarrhea, but our doctor adjusted the dose, and now all is going well."

10 / 10
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57 Report
  • Ano...
  • Taken for 1 to 2 years
  • April 19, 2025

Abemaciclib "I had a lot of diarrhea for several months. Then I started taking anti-diarrhea medication at the same time that I took Verzenio, and I didn't have as much diarrhea."

9 / 10
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4 Report

More FAQ

  • Sur...
  • Taken for 6 months to 1 year
  • August 27, 2020

Abemaciclib "This drug Verzenio shrank my tumor in my sternum a lot. I have now had it successfully removed."

9 / 10
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39 Report
  • Ama...
  • Taken for 1 to 6 months
  • August 12, 2024

Abemaciclib "Some diarrhea, and fatigue. Otherwise, it’s easy to take and doesn’t bother me."

9 / 10
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9 Report
  • kan...
  • Taken for 6 months to 1 year
  • March 31, 2025

Abemaciclib "First 6 months... diarrhea twice a week... now hardly ever have this side effect for the last 5 months. Have given up sugar too."

8 / 10
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3 Report
  • Mar...
  • Taken for 1 to 2 years
  • December 3, 2023

Abemaciclib "Side effects can be troublesome. I have learned to deal with side effects so I can enjoy life."

10 / 10
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11 Report
  • BP1...
  • Taken for 1 to 6 months
  • May 3, 2023

Abemaciclib "I experienced stomach cramps, severe diarrhea, elevated blood pressure, and stomach bloating while taking this."

6 / 10
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13 Report
  • dmo...
  • February 3, 2025

Abemaciclib "I have had on and off liquid diarrhea since starting Verzenio with a pill related to Faslodex (not approved yet - Giredestrant)"

6 / 10
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  • kar...
  • Taken for 1 to 2 years
  • July 2, 2025

Abemaciclib "Started with 150. Couldn't take side effects. Down to 50mg 2x a day plus anastrozole. Have diarrhea daily...used to it. Tired...naps 2x a day. Bone pain as well. Hope it's all worth it."

6 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

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