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Abemaciclib User Reviews & Ratings (Page 2)

Brand names: Verzenio

Abemaciclib has an average rating of 7.7 out of 10 from a total of 41 reviews on Drugs.com. 59% of reviewers reported a positive experience, while 7% reported a negative experience.

Reviews for Abemaciclib

Commonly mentioned side effects
  • ann...
  • Taken for 1 to 6 months
  • January 4, 2025

Abemaciclib for Breast Cancer "Took for 5 months, beginning of March 2024 to the last week of July 2024. Occasional diarrhea, treated effectively with diarrhea medication. July 2024, began having shortness of breath. Last week of July, went to my pulmonologist. Chest CT done. I had pneumonitis, bilateral. Hospitalized for 2 days. Treated with corticosteroids. On discharge, treated with oral prednisone. Started with 40 mg, then weaned off initially after 4 weeks, then restarted for another 4 weeks. Last dose was the 3rd week of October. Pneumonitis resolved."

7 / 10
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4 Report
  • Vio...
  • Taken for 1 to 2 years
  • February 4, 2024

For Breast Cancer "Side effects (Over 1 year and the below continues constantly): Fatigue, decreased energy, hair thinning, upset stomach, bloating, body ache, hand numbness and tingling, increased weight, decreased appetite, blurred vision, diarrhea, upper right abdomen inflammation, mental fog."

8 / 10
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5 Report
  • Ano...
  • Taken for 1 to 2 years
  • May 22, 2025

For Breast Cancer "Diarrhea, fatigue, decreased stamina, muscle aches, and watery eyes, which I find very annoying and embarrassing. I can end up with crusted salt marks on my face. Hair thinning, lower immunity, and raised LFTs, neutropenia. The diarrhea causes anxiety when out, as I enjoy walking and cycling, so often no toilets around. I am taking adjuvant abemaciclib and on cycle 21, but still taking 150 mg twice daily."

5 / 10
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Frequently asked questions

  • AAd...
  • Taken for 1 to 2 years
  • July 10, 2025

Abemaciclib for Breast Cancer "It’s been tough with this medication. I've had the common side effects. I was on it for 8 months at 150 mg twice daily before being taken off after developing organizing pneumonia. It took 4 weeks after hospitalization to realize it wasn’t bacterial. I stayed off the medication for 10 months, then was put back on at 100 mg twice daily—only to be taken off again after 8 months when the pneumonia returned. My pulmonologist and oncologist don’t think I can go back on Verzenio. I have an appointment with my oncologist in a couple of weeks to discuss this further, as I haven’t seen her since I was advised by both specialists to stop taking it. I know I’m supposed to be on Verzenio for two years, so I’m naturally concerned since I don’t seem to tolerate it. I want to advocate for an alternative, but I’m not sure what that could be. I also wonder if there’s any way to take Verzenio without triggering these lung issues. It’s disheartening."

3 / 10
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  • Ano...
  • Taken for 1 to 2 years
  • June 24, 2025

Abemaciclib for Breast Cancer "I have been taking this for 18 months of the 2 years I am supposed to take it but am thinking of asking the consultant if I can come off it. I suffered initially with severe diarrhea but not for too long, however, the initial dose of 100 mg twice daily gave me excruciating lower abdomen pain, so this was dropped back to 50 mg twice daily and that dose suited me. As my infection resistance has, I believe, diminished over the months last year, I repeatedly had UTIs which, in the end, the GP put me on a preventative dose of Trimethoprim 100 mg daily. 10 months down the line, this is now not holding back the infection, which is why, amongst other things which are getting worse, I will be having the discussion with my consultant. Other side effects are now blood in my urine (which could be the long-term antibiotics), I am much more tired and have more bad days than good, aches in my hips and legs, sore gums, and sometimes no appetite at all."

8 / 10
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  • Ano...
  • Taken for less than 1 month
  • July 5, 2025

Abemaciclib for Breast Cancer "Besides diarrhea, vomiting, I became very light-headed, even when sitting down. Almost fell about 3 times, twice when in the shower. The light-headedness has continued for 2 weeks even after the doctor told me to stop taking it. I'm hoping this is not permanent, as it has made ordinary daily tasks extremely difficult."

3 / 10
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  • Tuc...
  • Taken for 1 to 2 years
  • September 20, 2020

Abemaciclib for Breast Cancer "I have been on Verzenio for 14 months. After 2 months, it shrank my tumor by 60%, and after 12 months, bone mets were almost gone. A 12-month PET scan showed no active cancer cells."

10 / 10
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59 Report

More FAQ

  • Luc...
  • Taken for 6 months to 1 year
  • February 19, 2020

Abemaciclib for Breast Cancer "Verzenio has worked after my wife’s initial treatment failed and her cancer returned. She had some initial diarrhea, but our doctor adjusted the dose, and now all is going well."

10 / 10
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57 Report
  • Sur...
  • Taken for 6 months to 1 year
  • August 27, 2020

Abemaciclib for Breast Cancer "This drug Verzenio shrank my tumor in my sternum a lot. I have now had it successfully removed."

9 / 10
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39 Report
  • Ano...
  • Taken for 1 to 2 years
  • April 19, 2025

Abemaciclib for Breast Cancer "I had a lot of diarrhea for several months. Then I started taking anti-diarrhea medication at the same time that I took Verzenio, and I didn't have as much diarrhea."

9 / 10
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4 Report
  • Ama...
  • Taken for 1 to 6 months
  • August 12, 2024

Abemaciclib for Breast Cancer "Some diarrhea, and fatigue. Otherwise, it’s easy to take and doesn’t bother me."

9 / 10
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9 Report
  • Mar...
  • Taken for 1 to 2 years
  • December 3, 2023

Abemaciclib for Breast Cancer "Side effects can be troublesome. I have learned to deal with side effects so I can enjoy life."

10 / 10
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11 Report
  • BP1...
  • Taken for 1 to 6 months
  • May 3, 2023

Abemaciclib for Breast Cancer "I experienced stomach cramps, severe diarrhea, elevated blood pressure, and stomach bloating while taking this."

6 / 10
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13 Report
  • kan...
  • Taken for 6 months to 1 year
  • March 31, 2025

Abemaciclib for Breast Cancer "First 6 months... diarrhea twice a week... now hardly ever have this side effect for the last 5 months. Have given up sugar too."

8 / 10
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  • dmo...
  • February 3, 2025

Abemaciclib for Breast Cancer "I have had on and off liquid diarrhea since starting Verzenio with a pill related to Faslodex (not approved yet - Giredestrant)"

6 / 10
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  • kar...
  • Taken for 1 to 2 years
  • July 2, 2025

Abemaciclib for Breast Cancer "Started with 150. Couldn't take side effects. Down to 50mg 2x a day plus anastrozole. Have diarrhea daily...used to it. Tired...naps 2x a day. Bone pain as well. Hope it's all worth it."

6 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.