Thrombotic Thrombocytopenic Purpura
Medically reviewed by Drugs.com. Last updated on Apr 6, 2025.
TTP is a blood disorder that causes anemia and bleeding problems due to low platelet levels. Anemia is low levels of red blood cells. Without enough platelets, you can bleed in your organs, underneath your skin, or from the surface of your skin. TTP can also cause problems with kidney and brain function.
DISCHARGE INSTRUCTIONS:
Call 911 for any of the following:
- You have any of the following signs of a heart attack:
- Squeezing, pressure, or pain in your chest
- You may also have any of the following:
- Discomfort or pain in your back, neck, jaw, stomach, or arm
- Shortness of breath
- Nausea or vomiting
- Lightheadedness or a sudden cold sweat
- You have any of the following signs of a stroke:
- Numbness or drooping on one side of your face
- Weakness in an arm or leg
- Confusion or difficulty speaking
- Dizziness, a severe headache, or vision loss
- You cough up blood.
- You have trouble breathing.
Return to the emergency department if:
- Your heart is beating faster than usual.
- You urinate less than usual or not at all.
- Your skin or the whites of your eyes are yellow.
- Your arm or leg feels warm, tender, and painful. It may look swollen and red.
Contact your healthcare provider if:
- You have a fever.
- You have bruises or small red or purple dots on your skin or mucus membranes.
- You have questions or concerns about your condition or care.
Drugs used to treat this and similar conditions
Doptelet
Doptelet (avatrombopag) is used to treat thrombocytopenia in patients with chronic liver disease ...
Otezla
Otezla (apremilast) is used to treat plaque psoriasis, psoriatic arthritis, and oral ulcers ...
Promacta
Promacta is used to prevent bleeding episodes in patients with chronic immune (idiopathic) ...
Adzynma
Adzynma (ADAMTS13, recombinant-krhn) is a human recombinant protein that may be used to prevent or ...
Romiplostim
Romiplostim (Nplate) stimulates thrombopoietin production and may be used to treat low blood ...
Rituximab
Rituximab is a monoclonal antibody drug used to treat non-hodgkin lymphoma, chronic lymphocytic ...
Dexamethasone
Dexamethasone is used to treat inflammatory conditions such as allergies, skin conditions ...
Avatrombopag
Avatrombopag systemic is used for immune thrombocytopenia, thrombocytopenia
Apadamtase alfa, recombinant
Apadamtase alfa, recombinant systemic is used for thrombotic thrombocytopenic purpura
Treatment options
The following list of medications are related to or used in the treatment of this condition.
Do not take over-the-counter medicines before you talk to your healthcare provider:
This includes NSAIDs, vitamins, and herbal supplements. These medicines can make TTP worse. Ask your healthcare provider for a full list of medicines you should not take.
Do not play contact sports:
Examples of contact sports include football, wrestling, boxing, or hockey. Ask your healthcare provider which activities are safe for you.
Do not drink or eat anything that contains quinine:
Quinine can make TTP worse. Quinine is found in tonic water, flavored drinks, and some foods. Read all food and drink labels to check for quinine. Ask your healthcare provider for a full list of drinks and foods that contain quinine.
Follow up with your healthcare provider as directed:
You will need to return for blood and urine tests. You may need plasmapheresis or plasma transfusions 1 time each week. Write down your questions so you remember to ask them during your visits.
© Copyright Merative 2025 Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.
Learn more about Thrombotic Thrombocytopenic Purpura
Treatment options
Care guides
Symptoms and treatments
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.