R-Chop Chemo Regimen
Medically reviewed by Drugs.com. Last updated on Dec 2, 2024.
R-CHOP chemo regimen:
Your doctor will prescribe your dose and schedule. You will receive these medicines while you are in a hospital or cancer treatment center. The medicines need to be given on a fixed schedule. If you need to miss a dose, call your doctor or treatment clinic immediately. The following infusion cycle usually repeats every 21 days for 8 cycles:
- Rituximab IV, day 1 (may be given on a different day from the other IV medicines)
- Cyclophosphamide IV, day 1
- Doxorubicin IV, day 1
- Vincristine IV, day 1
- Prednisone oral, days 1, 2, 3, 4, and 5
Before you receive these medicines:
- Your doctor may adjust the dose of some medicines based on your age and any health conditions you have.
- Ask questions if you do not understand what your doctor or nurse is telling you about the medicines. Make sure you understand all the risks and benefits of this treatment.
- Talk to your doctor about all your current medicines and supplements. Do not take any medicines or supplements unless they have been discussed with your doctor.
On each infusion day:
- Blood may be drawn to make sure the doses you are being given are right for you.
- Medicines may be given to help with nausea and vomiting and to decrease your risk for reactions.
Infusion precautions:
- Contact your doctor or nurse immediately if you feel short of breath or have trouble breathing during or after your infusion.
- Tell the doctor or nurse right away if you notice redness, pain, or swelling at the infusion site.
After each infusion:
- If possible, have someone stay with you to call for help if you have serious side effects.
- Drink extra liquids to help prevent nausea and to keep your kidneys working well.
- You may be at risk for infections. Wash your hands often with soap and water. Do not have close contact with anyone who is sick. Ask your doctor about vaccines you may need to prevent infections.
Call your local emergency number (911 in the US) if you have any of the following:
- Chest pain or pressure, fast, pounding, or irregular heartbeat
- Seizures, confusion
- Hives, swelling in your lips, face, or throat, headache, lightheadedness, fainting, flushing
Call your nurse or doctor immediately if you have any of the following:
- Unusual bleeding or bruising, blood in your urine or bowel movement, decrease in urine amount
- Eye pain, trouble seeing, vision changes, not being able to move your eyeball
- Pain in your upper stomach, severe stomach pain
- Mood changes, confusion, depression, or unusual thoughts, feelings, or behaviors
- Muscle or nerve pain, numbness or tingling in your hands or feet
Talk to your nurse or doctor if you have any of the following:
- Fever, chills, body aches, cough, sore throat
- Stomach cramps, nausea or vomiting, diarrhea, constipation, loss of appetite, weight loss
- Changes in skin or nail color
- Round, puffy face, headache
- Skin rash or itching, hair thinning or loss, night sweats, mouth sores
- Pain, redness, swelling, itching, irritation at the infusion site
Follow up with your oncologist as directed:
Your oncologist will need to check your progress at regular visits. Blood tests may be needed to check for side effects.
Care Agreement
You have the right to help plan your care. Learn about your health condition and how it may be treated. Discuss treatment options with your healthcare providers to decide what care you want to receive. You always have the right to refuse treatment. The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.© Copyright Merative 2024 Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
Further information
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