Generic Name: Sulfadiazine (sul fa DYE a zeen)
Medically reviewed on September 5, 2018
Uses of Sulfadiazine:
- It is used to treat or prevent bacterial infections.
What do I need to tell my doctor BEFORE I take Sulfadiazine?
For all patients taking sulfadiazine:
- If you have an allergy to sulfadiazine or any other part of sulfadiazine.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are pregnant and near term.
- If you are breast-feeding. Do not breast-feed while you take sulfadiazine.
- If your child is younger than 2 months of age. Do not give sulfadiazine to an infant younger than 2 months of age.
This is not a list of all drugs or health problems that interact with sulfadiazine.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take sulfadiazine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Sulfadiazine?
- Tell all of your health care providers that you take sulfadiazine. This includes your doctors, nurses, pharmacists, and dentists.
- Do not use longer than you have been told. A second infection may happen.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Be careful if you have G6PD deficiency. Anemia may happen.
- Talk with your doctor before you drink alcohol.
- You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using sulfadiazine while you are pregnant.
How is this medicine (Sulfadiazine) best taken?
Use sulfadiazine as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- To gain the most benefit, do not miss doses.
- Keep taking sulfadiazine as you have been told by your doctor or other health care provider, even if you feel well.
- Take with or without food.
- Take with a full glass of water.
- Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
- Not able to pass urine or change in how much urine is passed.
- Change in color of skin to a bluish color like on the lips, nail beds, fingers, or toes.
- Pale skin.
- Very bad dizziness or passing out.
- Chest pain or pressure or a fast heartbeat.
- Hallucinations (seeing or hearing things that are not there).
- Joint pain.
- Mouth irritation or mouth sores.
- Sore throat.
- Vaginal itching or discharge.
- Purple patches on the skin or mouth.
- It is common to have diarrhea when taking sulfadiazine. Rarely, a very bad form of diarrhea called Clostridium difficile (C diff)–associated diarrhea (CDAD) may occur. Sometimes, this has led to a deadly bowel problem (colitis). CDAD may happen while you are taking sulfadiazine or within a few months after you stop taking it. Call your doctor right away if you have stomach pain or cramps, very loose or watery stools, or bloody stools. Do not try to treat loose stools without first checking with your doctor.
- Rarely, very bad effects have happened with sulfa drugs. Sometimes, these have been deadly. These effects have included liver problems, blood problems, and very bad skin reactions (Stevens-Johnson syndrome/toxic epidermal necrolysis). Call your doctor right away if you have a rash; red, swollen, blistered, or peeling skin; red or irritated eyes; sores in your mouth, throat, nose, or eyes; fever, chills, or sore throat; cough that is new or worse; feeling very tired or weak; any bruising or bleeding; or signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
What are some other side effects of Sulfadiazine?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Upset stomach or throwing up.
- Loose stools (diarrhea).
- Not hungry.
- Not able to sleep.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Sulfadiazine?
- Store tablets at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Protect from light.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about sulfadiazine, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about sulfadiazine
- Sulfadiazine Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- Drug class: sulfonamides