Generic Name: Gemcitabine (jem SITE a been)
Brand Name: Gemzar, Infugem
Medically reviewed by Drugs.com. Last updated on Aug 15, 2020.
Uses of Gemcitabine:
- It is used to treat cancer.
What do I need to tell my doctor BEFORE I take Gemcitabine?
- If you are allergic to gemcitabine; any part of gemcitabine; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you are getting radiation.
- If you are breast-feeding. Do not breast-feed while you take gemcitabine and for 1 week after your last dose.
This is not a list of all drugs or health problems that interact with gemcitabine.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take gemcitabine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Gemcitabine?
- Tell all of your health care providers that you take gemcitabine. This includes your doctors, nurses, pharmacists, and dentists.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- If you have had or will be having radiation treatment, talk with your doctor. Worse side effects from radiation treatment have happened with gemcitabine.
- Capillary leak syndrome (CLS) is a very bad health problem that has happened with gemcitabine. Sometimes, CLS can be deadly. Tell your doctor right away if you get signs of CLS like change in how much urine is passed; not able to pass urine; blood in the urine; a fast or abnormal heartbeat; chest pain or pressure; dizziness or passing out; shortness of breath; a big weight gain; swelling; throwing up blood or throw up that looks like coffee grounds; or if you have black, tarry, or bloody stools.
- This medicine may cause very bad and sometimes deadly lung problems. Call your doctor right away if you have trouble breathing. These lung problems can happen up to 2 weeks after gemcitabine is stopped.
- A very bad and sometimes deadly brain problem called posterior reversible encephalopathy syndrome (PRES) has happened with gemcitabine. Call your doctor right away if you have signs like feeling confused, lowered alertness, change in eyesight, loss of eyesight, seizures, or very bad headache.
- A blood problem called hemolytic uremic syndrome (HUS) has happened with gemcitabine. Severe kidney problems have happened and sometimes dialysis was needed. Sometimes, these kidney problems have been deadly. Call your doctor right away if you feel very tired or weak or have any bruising or bleeding, change in how much urine is passed, confusion, dark urine, fast heartbeat, fever, mood or behavior changes, pale skin, seizures, shortness of breath, stomach pain, or throwing up.
- This medicine may irritate the vein. If the drug leaks from the vein, it may also cause irritation around that area. Tell your nurse if you have any redness, burning, pain, swelling, or leaking of fluid where the drug is going into your body.
- If you are 65 or older, use gemcitabine with care. You could have more side effects.
- This medicine may affect being able to father a child. It is not known if this effect will go back to normal.
- Men with a partner who may get pregnant must use birth control while taking gemcitabine and for some time after the last dose. Ask your doctor how long to use birth control. If your partner gets pregnant, call the doctor right away.
- This medicine may cause harm to an unborn baby. A pregnancy test will be done before you start gemcitabine to show that you are NOT pregnant.
- Women must use birth control while taking gemcitabine and for some time after the last dose. Ask your doctor how long to use birth control. If you get pregnant, call your doctor right away.
How is this medicine (Gemcitabine) best taken?
Use gemcitabine as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of bleeding like throwing up or coughing up blood; vomit that looks like coffee grounds; blood in the urine; black, red, or tarry stools; bleeding from the gums; abnormal vaginal bleeding; bruises without a cause or that get bigger; or bleeding you cannot stop.
- Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Signs of electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, seizures, not hungry, or very bad upset stomach or throwing up.
- Very bad dizziness or passing out.
- A burning, numbness, or tingling feeling that is not normal.
- Very bad and sometimes deadly liver problems have happened with gemcitabine. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
What are some other side effects of Gemcitabine?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Hair loss.
- Flu-like signs. These include headache, weakness, fever, shakes, aches, pains, and sweating.
- Not hungry.
- Mouth irritation or mouth sores.
- Feeling tired or weak.
- Feeling sleepy.
- Constipation, diarrhea, throwing up, and upset stomach are common with gemcitabine. If these happen, talk with your doctor about ways to lower these side effects. Call your doctor right away if any of these effects bother you, do not go away, or get very bad.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Gemcitabine?
- If you need to store gemcitabine at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about gemcitabine, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about gemcitabine
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Compare Alternatives
- Pricing & Coupons
- En Español
- 6 Reviews
- Drug class: antimetabolites
- FDA Alerts (1)