Medically reviewed on September 5, 2018
Uses of Alphanate:
- It is used to treat von Willebrand disease.
- It is used to treat or prevent bleeding.
- Some products are used to treat hemophilia. Talk with the doctor.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Alphanate?
- If you have an allergy to Alphanate (antihemophilic factor/VWF complex (human)) or any part of Alphanate (antihemophilic factor/VWF complex (human)).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Alphanate (antihemophilic factor/VWF complex (human)) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Alphanate?
- Tell all of your health care providers that you take Alphanate (antihemophilic factor/VWF complex (human)). This includes your doctors, nurses, pharmacists, and dentists.
- Allergic side effects may rarely happen.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Blood clots have happened with Alphanate (antihemophilic factor/VWF complex (human)). Tell your doctor if you have ever had a blood clot. Talk with your doctor.
- Call the doctor right away if the normal dose does not work as well.
- This medicine is made from human plasma (part of the blood) and may have viruses that may cause disease. This medicine is screened, tested, and treated to lower the chance that it carries an infection. Talk with the doctor.
- Talk with the doctor before you travel. You will need to bring enough of Alphanate (antihemophilic factor/VWF complex (human)) for use during travel.
- If you are 65 or older, use Alphanate (antihemophilic factor/VWF complex (human)) with care. You could have more side effects.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Alphanate (antihemophilic factor/VWF complex (human)) while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Alphanate) best taken?
Use Alphanate (antihemophilic factor/VWF complex (human)) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into a vein.
- If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
- Follow how to use as you have been told by the doctor or read the package insert.
- Wash your hands before and after use.
- This medicine needs to be mixed before use. Follow how to mix as you were told by the doctor.
- Do not shake.
- Do not use if solution changes color.
- Throw away any part of the opened vial not used after the shot is given.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
- Use within 3 hours of making.
- There may be a few flakes or particles after you mix Alphanate (antihemophilic factor/VWF complex (human)). The filter used when mixing Alphanate (antihemophilic factor/VWF complex (human)) removes these from the solution. Do not use if the solution is cloudy, leaking, or still has flakes or particles after using the filter.
What do I do if I miss a dose?
- Skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- If you are not sure what to do if you miss a dose, call your doctor.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of certain infections (parvovirus B19, hepatitis A) like fever or chills, feeling very sleepy, runny nose, rash, joint pain, tiredness, poor appetite, upset stomach or throwing up, belly pain, or yellow skin or eyes.
- Very bad dizziness or passing out.
- Very bad headache.
- A burning, numbness, or tingling feeling that is not normal.
- Very upset stomach or throwing up.
- Feeling very tired or weak.
- Dark urine or yellow skin or eyes.
- A fast heartbeat.
- Change in color of mouth to blue.
- Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
- Call your doctor right away if you have signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking or swallowing.
What are some other side effects of Alphanate?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Alphanate?
- Store at room temperature. Do not freeze.
- Store in original container.
- Protect from light.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Alphanate (antihemophilic factor/VWF complex (human)), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Alphanate (antihemophilic factor / von willebrand factor)
- Alphanate Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: miscellaneous coagulation modifiers