Wellbutrin severe allergic reaction - How long does the itching last?

I know this question is from 8.5 years ago but it is SO NICE to read about other people's experiences with wellbutrin that are similar to mine. My doc put me on bupropion XL 150mg and I started taking it about 2.5 weeks ago. I didn't experience the common side effects too badly, but I was cranky and had a headache for the first week. 4 days ago I woke up with most insane hives on my thighs and armpit area. My hands and wrists were so swollen that I couldn't use them. Doc put me on prednisone and cetizirine to relieve the hives. I just moved and got a new mattress so I figured it was one of those that triggered these hives but I'm starting to think otherwise since I've never been allergic to mattresses or moving before... Still waking up everyday with new hives but not as intense as the first episode. Going to go off the wellbutrin and see how it goes!

Was taking bupropion 75mg (Wellbutrin SR) once every other day (NOT recommended by my nurse practitioner) for about 3 weeks. Felt some pain/discomfort from nerve/muscle pain after about 3 weeks.. which I did not experience before taking Wellbutrin. Have read up on very few people experiencing nerve/muscle discomfort from Wellbutrin. Stopped taking it for that reason. Once in a while still, at night, I'm feeling strange mild itchy feeling which feels nerve-related. Going to see what happens, if not resolved, seeing my doctor ASAP.

Another odd side effect, increased appetite? Really wish I could keep taking Wellbutrin because I am normally a stick and was enjoying the increased appetite/ potential weight gain!! It also improved my sex drive and mood. :( Really sad it didn't work. If I find out the discomfort wasn't due to it, I may try again.

I wound up taking Wellbutrin for 30 days exactly, the itching began at around 2 weeks and it was unbearable by the 30th day. I was taking a Benadryl every night to be able to sleep. When my month prescription was over, I called my doctor for the second time about it and she said to stop taking it. A couple of weeks later, no meds, the itching was still there, and she convinced me to try Prozac (mind you, these were both prescribed because they have a possible side effect of weight loss, so not even for anxiety or depression). I took that and IMMEDIATELY started having problems with high blood pressure and after about three weeks, a full blown panic attack or something that I thought was a heart attack and wound me up in the ER. I stopped taking that as well at that point and my BP got better right away but I was still itching. All in all, the itching took at least 3 months to stop, probably closer to 4.

I would have to say that it probably depends on the person, but for me personally it took 3 weeks to go away.

I began taking Wellbutrin and several weeks later began itching in my eyes, hands and feet (and other sensitive areas!) it became more severe over several days as I tried lotions, oatmeal baths, topical anti-itch sprays and creams - finally realizing it was an allergic reaction. I took Allegra and it went away. I tapered off the Wellbutrin over a week ago. But every time I stop taking the Allegra the itching comes back (at night for some reason). Sometimes its mild and sometimes more severe. I read that Wellbutrin stays in your system for weeks!

I started bupropion a couple of weeks ago for the first time - 150mg for a week and now into 300mg. I itched around my torso and feet suddenly a few days ago - very strange - thought it was dry skin. Didn’t realize this was a potential side effect. I have continued taking it so far and my itching has lessened - pockets in the groin area - very uncomfortable!

I had been on the generic Wellbutrin 150 mg for exactly 30 days. After about 3 weeks the itching started and it was insane. I didn't realize it was the medication at first, I tried to narrow down the things I had eaten and whether I had changed any soaps, but none of that applied. Then I realized that it may have been the medicine building up in my system. I stopped taking the medicine at day 30 and that was two and a half weeks ago. I am still itching terribly and have begun to get hives particularly on my shoulders. I called the doctor for the second time, who prescribed prednisone and I am to keep taking Benadryl as needed. My itching starts around 10 in the morning and gets progressively worse. I can't take benadryl during the day because it knocks me out but in the evening when I get home, I have to take one just so I don't say up itching all night.

I've been on 150 mg of wellbutrin for about 2 weeks. Today my scalp started itching, followed by my hands and feet. Soon my scalp broke out in hives and I left work. By the time I got home (about a mile and a half drive) I had hives all over my neck, back, thighs and stomach. I grabbed the first thing i could find which was lavender and frankincense essential oils, mixed them with a little coconut oil, and rubbed it all over my body. I felt immediate relief. I followed up with allegra and was able to come back to work. I also have some serious heartburn. Have put in several calls to my Dr. and am waiting for a call back. I will not be taking any more of this drug unless they tell me I need to ween off of it.

Took the 150 mg and 4 days ago started the 300 mg. Now I have hives head to toe starting today. It's every where but feet and hands are the worst itching. Too late today I took it then looked it up. Threw them away. Never again I'd rather smoke then deal with this.

I have been on generic Wellbutrin XL 150mg for almost 3 weeks and did the same thing, broke out in hives all over, head, bottom of feet, in the palms of my hand, arms, all over my legs I’m taking Benadryl, Claritin, and some unused prednisone from a couple of months ago. I called my pharmacist yesterday (6/12/18) to ask him if he thinks it’s the Wellbutrin and he said no. I asked him it the brand name would make a difference compared to generic and he said no to that too. But from what I’ve read it is the medication so I’ve just stopped taking it. Hopefully the itching will stop soon!

I was on Wellbutrin for years without any side effects. Then out of nowhere for a whole year I begin breaking out in hives/rash different areas of my body went to the Dr. over and over again,different meds. Was diagnosed with chronic hives. Than 1 day in January of this year within 30 mins.of taking it had a severe reaction shortness of breath and swelled up. That's when i realized it was the med. Stopped taking it within the week no rash/hives.

I was on 150 wellbutrin and increased to 300 in January 2018. I have had a full body rash, arms, legs, back, stomach, with severe off the chart itching for 5 months. I had no idea until i read this blog this morning that Wellbutrin was my problem!! I am going to wean myself off this drug asap and go see my Doctor. Absolutely thrilled to finally know what is causing it. I have been taking Allegra in am and benadryl at might, hasnt helped. grateful for this blog!!!