... years and it worked great, but it was so expensive. So, I recently started taking 2-20mg over the counter pills a day instead of the 1-40mg tablet …my pharmacist said this should be the same thing. It isn't working! I have had acid reflux and heartburn worse than I've had in 2 years. Can the over the counter pills really be THAT different, or is it a coincidence that my symptoms have flared up at the same time I switched over? I haven't changed my diet or anything else in my lifestyle recently and I have been under no stress recently. Has anyone else shared this type of complaint?
Probably just different enough to set a rebound off , I would try doubling up on 40mg and / or take anti acids or h2 blocker until I got my acid under control , then back off to normal amount . My g.i. Doc does that when he has switch meds or sometimes just when I get same pills with different manufacturers . Ask your g.i. First thou I hope you find relief
There should be no difference. Its the same manufacturer as the prescription ones.
It may be time for you to change brands. That happens sometimes when you go off and try to go again.
I too am having the identical issue when switching from Rx to OTC. Am taking 2-20mg per day, and it is not working for me either. Effective 10/1/14, my doctor must pre-certify my Rx AND my co-pay has increased dramatically, making the Rx unaffordable. Has anyone has success with alternative generics? I finally had my GERD under control, so this is very frustrating.
I'm having the same problem. Just wanted to let you know that you're not crazy. :)
Nexium 24Hr OTC is not working for me either! I have taken Nexium 40mg RX for over 3 years with most of my GERD/ LPR symptoms under control. In addition, I have been on Nexium and other long term PPIs for 23 years now. My insurance will no longer cover the Nexium 40mg RX prescription. I decided to try taking (2) of the Nexium 24Hr OTC/day. I am now suffering a terrible increase in stomach acid and my GERD / LPR symptoms are way out of control! I have decided to continue to see if this might be some type of rebound effect from stopping the RX version suddenly, so I have continued to give Nexium 24Hr more time. But as of today, it has been 6 weeks since the change. I truly believe Nexium 24Hr OTC does NOT work anything like the Nexium RX prescription version! In another week or so if I still see no change or symptoms continuing to get worse, I believe I will have to give Dexilant or another alternate PPI a try.
I gave the over the counter a bit longer, and now it seems to be working fine. Not sure why the first few months wasn't going well, but my body seems to have adjusted now. Thankfully.
I called AstraZeneca and they have informed me that they have no clinical proof yet that two 20mg Nexium is or isn't the same as one 40mg. However, they did say that they have been receiving numerous calls saying two 20mg does not work the same as one 40gm Nexium. For me it does not work the same.
where are you getting 20mg ? the OTC are 23 mg? are they not?
and this commercial that I saw said we can get 40mg by prescription for 15 $
How does that work if the insurance won't approve the request
Like all of you, I have not responded well to OTC Nexium after using it for over a month. I was on RX 40 mg 1-2 a day for over 12 years to control my GERD and Barrettes Esophagus. Had to fight with my insurance last year & finally got approval 10/28/14 and they took it away 1/1/15. I went straight from the Rx to the OTC, taking 2-20 mg OTC, expecting it to work. I then went to 2 doses a day, to no avail. Insurance claims it's the exact same. I've been researching & found OTC has corn starch, ferric oxide, sucrose & pharmaceutical ink not in RX. RX has sugar spheres and some things in the capsule shell. Perhaps it is the iron in the OTC that is aggravating all of us. Both Astra Zeneca & Pfizer are collecting information like this from patients so please call them. They can transfer you from one to the other so it should be only one call. Only if we stand up for our own health, can we make the insurance companies listen. I'm still fighting.
My Doctor told me that Generic drugs were the SAME INGREDIENTS,,, but there is either 20% more or 30% less in every lot, so what you were taking could be different from the last generic prescription... could it be that this over the counter Nexium has this "problem" also??? I have not tried the over the counter Nexium but was going to try it... not now. BTW, your pharmacist SHOULD tell you about the generic differences, but many DO NOT>>>>>
I take the "newly released" generic by Teva USA. 40mg same as my nexium I was taking... and I have had breakthrough acid reflux everyday regardless of what I do. I can drink water and it just hangs out and of I lean over I can feel it move up my throat. This stuff SUCKS!!! However I am not willing to pay the outrageous copay to get brand. So I am going to talk to my doctor about switching to a different med. I can't keep taking 40 mg of crap nexium and then later taking 150mg of zantac because I keep having breakthrough. Anyone know a good generic like protonix or dexilant?
I have been on Rx Nexium for decades because of Barretts and reflux, 40 mg daily and was doing very well until I changed to OTC, 2x20 mg. My reflux isn't horrible, but it's definitely increased. My biggest problem is I'm getting nausea and bouts of pretty severe diarrhea. It took me a while to connect the two, but after reading all your helpful comments, I do believe it's the OTC Nexium. I know these can be side effects and had very mild symptoms on the Rx. I just don't trust generic meds, I tried the generic Celebrex and was that ever a disaster. And who knows really what goes into the drugs anymore, especially those manufactured offshore.
Check out People's Pharmacy for more discussion. I find them very helpful.
I had the same response when I converted to over the counter Nexium. Something has to be different but I haven't found anyone with answers. I expected it to be the same or better but there was less control of the heartburn, more reflux at night.
Well, just to add to the "we're not crazy"... I have been trying to stop take Nexium 40MG for years. Every few years, I try a different PPI or generic, and always end up relapsing and having to return. I recently read all the posts about how Prilosec is basically just half-strength Nexium. So, I tried taking 80MG of that - unfortunately, after only about 5 weeks later, I was back to Nexium. When they released the OTC 20MG version (from a different manufacturer yup but supposedly required to have the same active ingredients)... I immediately bought the big 42 quantity packs when they were on sale and started doubling up with (2) 20MG OTC Nexium every day. For the first 2-3 months, it worked the best of all the things I have tried to switch to and I didn't really notice any significant difference in feeling acidy.
I did however, enjoy the extra cash in my wallet, since like many of you, my insurance company refuses to cover Nexium and considers it exactly the same as all other PPI drugs and generics. Unfortunately, I started noticing I had sore throats frequently, losing my voice, or a little "lump" feeling in my throat. Sometimes even a weezy, asthma feeling after eating. Since this all happened over the winter/ early spring and had never been my symptoms of reflux in the past, I just naively assumed it was a cold or seasonal allergies. Well, once my hoarseness and clearing my throat wouldn't go away, I started looking up these symptoms and yep, back to the GERD. SO... unfortunately, I just requested again the Nexium 40MG very reluctantly. I don't like lining the pocket of pharmaceutical companies but for whatever reason, the odd chemistry in my body only seems to work with the exact formulation of the current prescription version. Luckily, it appears that they now have a Nexium "savings card" where I get my 90 day supply for $30 (or $0.33 per dose) which is much cheaper than my bargain-hunting-coupon-clipping $18 for the 42-count 20MG (costing me about $0.86 per dose to double up).
- Nexium Information for Consumers
- Nexium Information for Healthcare Professionals (includes dosage details)
- Side Effects of Nexium (detailed)
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