Have been on omeprazole for 1 1/2 months after being on nexium for a couple years and the feeling of a lump in my throat is back and I suffer from much gas. Can't afford nexium anymore due to 50% co-pay & mandatory 3 month renewals from mail order drug.With nexium I was symptom free almost all the time. very frustrating
Omeprazole is prilosec , nexium is a newer more advanced version both were patiented by same company only nexium has no generic form yet. If its been a month ± you need to find another , there are many choices . I would try lansoprazole (prevacid) it is on generic list and otc . I hope I helped and I hope you find relief
Astra-Zenica had the patent for omeprazole. Toward the end of the 17 year patent, the legal /technical brains at AZ thought about providing more profit streams, and wanted to patent "Nexium." Many thought they (AZ) couldn't do it, but they somehow got it through the FDA and got it patented.
"Nexium" is the s-isomer of omeprazole. Nexium is actually called esomeprazole. If you remember your chemistry (organic), an s-isomer is a mirror image of the "other" form. That's it. Look at your right hand, then look at your left hand. They are "s-isomers" of each other.
There is NO performance difference between Rx Nexium and OTC omeprazole/Prilosec.
It is just a way for AZ to improve profitability. They make no claim that Nexium, "the purple pill" works any better or worse than any other product (ie omeprazole). Why would they? There is no difference. Mirror image and more expensive.
Big pharm rip off. Buyer beware.
According to a government study, Nexium 40 MG (esomeprazole) provides more effective acid control than Prilosec 40 MG (omeprazole). I understand that there are some variabilities among people as one might work better for you than the other, but in a study of 135 people, the mean shows that Nexium works better. The link is below for you to read.
Years ago "no one" could give me an explanation as to the difference. Shortening the story i called the manufacturer and talked to some one im their lab. There is a molecular difference. Nexium im the process of manufacturing has been taken one step further. It does not have to go thru the liver to be effective. Something like pre digested milk would work. Probably reason for price difference. But when new i feel pharmaceutical company took advantage to those who had to have it and would cost $400. Good product tho.
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