Okay, another thing I'm contemplating is trying to take my Fluoxetine at night instead of the morning. I did this also when I was taking Cipralex (a.k.a. Lexapro/escitalopram) and it worked better for me, as if I'd take the Cipralex in the morning, I'd end up having to work my way through feeling sunken in below my eyes and really drowsy for a number of hours. So, I slept through those side effects when I took it at night. Bothersome side effects I'm still (after 4 weeks) having on the Fluoxetine: Lump in throat; feeling really cold after an hour of taking it for a few hours; aspirin taste in mouth that lasts most of the day; no appetite etc... When I first started taking it, I felt very drowsy and yawned a lot. So am thinking maybe I should give it a whirl and take it at night. Read differing opinions on this as well. Most sites say you should take it in the morning; a couple suggested taking it at night if you feel drowsy on it. It's strange, I feel both jittery & drowsy on it. Has anyone 'out there' ;-) taken Fluoxetine/Prozac at night instead of the morning; if so, why, and did that work better for you? Or anyone with an opinion/information about this particular question by all means feel free to share your insights -- very much appreciated!!! Annie B. (very curious as she wants to feel better as quickly as possible!!! )
Taking Fluoxetine (generic Prozac) at night instead of the morning?
Question posted by AnnieBHappy on 16 Feb 2013
Last updated on 6 July 2021 by WildcatVet
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40 Answers
It's purely a matter of personal preference depending on how the medication affects you. Every person responds differently so what works for one person may not work well for you. Do a little trial and error and you'll find what's best for YOU.
"Very common (10% or more of users): Headache (up to 21%), somnolence (up to 17%), tremor (up to 13%), dizziness (up to 11%)"
"Very common (10% or more of users): Insomnia (up to 33%), anxiety (up to 15%), nervousness (up to 14%)"
Best regards, Wildcat
PS, Somnolence = sleepiness/drowsiness.
I take it at night
New here. Started on Prozac 5 days ago. Gave me restless leg at night, so I switched to morning. Everything has been going fine until day 4 I woke up with insane anxiety. But not my normal anxiety. I was also prickly hot, hot, nauseas, increased HR, and an upset stomach. It finally subsided a few hours later. But I woke up again today with the same issues. My dr lowered my dose from 20mg to 10mg, and I have clonazepam for breakthrough anxiety. But also, now that I take the Prozac in the am, I am very sleepy. Does anyone take it mid day? Or have restless leg issues at night? And has anyone had these awful side effects? How long until they go away? I hate feeling like this around my child, and it makes me not want to leave the house in fear of a panic attack. It just stinks, because it seemed to be working wonders at first, but now my body and mind are all crazy.
I was told Fluoxetine will keep you awake and to take it as early in the day as possible. My psychiatrist told me this.
I’ve been on Prozac for some years now- reluctantly, as I’d FAR rather get talking therapy to resolve my problems than be continually ‘drugged up’. Because of this, I decided to reduce the dosage so, with my doctors knowledge & consent I’ve gone from 20mg (which left me like a zombie) to 10 which I now chop in half to make 5mls a day. The worst by far symptom for me has been bizarre & disturbing dreams. As a consequence, I’ve also decided to stop taking it at night and instead take it in the morning- which is what’s on the bottle anyway. It feels to me like a 2 edged sword; I think if I’d started taking it 20 years ago my life would have been dramatically better. But i can’t escape the bitter resentment I feel about the situation I was in that led to me feeling suicidal and visiting my doctor to demand that he give me medication stop the depression & overthinking.
I pleaded for counselling but it just didn’t happen
I just want to be ‘normal’ which I don’t think I’ll ever be on Prozac.
Hello. Not trying to be off topic but I have also been taking Prozac for almost a month now and this is my first time on any medication. I do take it at night because I feel more comfortable having the effects kicked in before I wake up. I was wondering if it was normal for you to feel after a month that you can't think and your spacey and out of it? Like u loose track of time or it takes u longer to do things and it's harder to think about how to do things? Thanks for anyone who replies.
I’ve been on Fluoxetine for around 4 years, I personally find it much more beneficial when I take it at night. One of my main symptoms of depression was fatigue in the morning, I find that the half-life of fluoxetine kicks in about 10 hours after I take it, which helps me when I wake up for work in the mornings. For a few months, about 2 years ago, I tried swapping to mornings as I was still jet lagged after travelling home, and it really didn’t have the same positive impact for me. I was getting drowsy super early in the evening and the mornings weren’t pleasant! I have no medical background but would say give it a go for a couple of weeks, as sleeping through some of the symptoms you’re getting might help you feel/function better in the daytime!
Hi... I have been taking this for 3 years. And I always take it at night. I take it just as u get into bed... And it works great.
I to feel very tired all day and then awake at night with anxiety taking this in the mornibg going into my 4th week on 20mg and am contimplating weaning myself off before i return to work in 2 weeks if i new i would break through this tiredness and lack of ambition to do anything i would continue but this seems to be reducing the quality of my life not enhancing it i too would like to know if anyone has had better success taking it at night
Annie-
I started taking my Prozac at night. That way I sleep through the "zombie" period. My doctor approved this change. I am doing better after 2 weeks. Still not perfect, but better.
I started taking fluoxetine 11 days ago and am really struggling to sleep. I’m taking it for anxiety that has led to disturbed sleep so my GP recommended taking it in the morning, so that I wouldn’t feel jittery by the time I go to bed. Then I would have a better chance of sleeping. To help me sleep though, i’I having to take zopiclone (a 3.75mg dose) which will give me 4-5 hours sleep. I’m reluctant to take 2 tablets as I know they can become addictive. (If I don’t take one, I sleep for about 2 hours and then can’t get back to sleep). I’m hoping this is a short term fix until the fluoxetine is absorbed and helps me sleep. Does anybody else have experience of taking it in the morning/evening who originally had disturbed sleep? Thank you
I've been on Prozac for about two years and have only ever taken it at night. My psychiatrist said that it doesn't matter when you take it because it is such a long-lasting drug. Morning, or night, it will still do its job. However, I have noticed that I am still rather tired even with taking it at night. Prozac definitely gives me fatigue as a side effect, but maybe for you it will be better at night. I would definitely try it! And as always just ask whoever is prescribing it to you just in case, but ^^that is my professional's opinion.
I've been alone Prozac since November 3rd and I find it really helpful in the mornings to get me through my days how you doing that taking it at night and helps you sleep but then you feel like on cloud nine all day until it wears off until you take your next dose at night so so far I'm I like the morning dosage for Prozac have a positive thoughts and I'm thankful for I would suggest this pill for anybody to take it in the morning even though we all are different and we work differently to meds
I have the same symptoms as you, I asked my doctor and he said that it make no difference what time you take it as long as you take it at the same time. I need a second opinion on this and I have an appointment to see a new doc.
I take it at night, and I'm tired all day, I'm thinking of changing to the morning.
Hi I'm tired throughout the day and awake at night. I am thinking of changing my fluxotine to night instead of morning. Will this help. Thanks pauline.
Post back after some time of trying this. Want to know if it works.
Related topics
lexapro, prozac, escitalopram, fluoxetine, generic
Further information
- Lexapro uses and warnings
- Prozac uses and warnings
- Escitalopram uses and warnings
- Fluoxetine uses and warnings
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