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Is there a generic for Lyrica?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on Oct 28, 2024.

Official Answer by Drugs.com

Yes, Lyrica (generic name: pregabalin) immediate-release capsules and oral solution are now available as a generic option in the US. Lyrica, the brand name product from Pfizer is also still available. Lyrica CR, which is an extended-release tablet formulation of pregabalin, is not yet available in a generic form.

In July 2019, the FDA approved pregabalin for the treatment of:

Generic pregabalin comes in strengths ranging from 25 mg to 300 mg per capsule. The generic oral solution comes as a pint-sized bottle (473 mL) containing 20 mg per mL.

See: Pregabalin dosing (in more detail)

Is generic Lyrica more affordable?

Yes, in most cases, cost-savings can be significant if you select a generic option over a brand name for your prescription.

The prices listed are for customers paying cash, but your cost may be different based on your pharmacy, location or if you have medication insurance. Prices are always subject to change, but generics often become even more affordable over time.

Learn More:

Are brand name and generic drugs both equally safe?

Yes, in most cases you can feel confident selecting a generic option at the pharmacy.

Is it OK to use generic Lyrica for seizures?

This is a controversial question. If you are using Lyrica to treat seizures, check with your doctor before making a generic substitution.

Using generic options in patients with seizures is controversial because studies have come to differing conclusions of the impact on seizure control. Switching between generic products and different manufacturers may also cause issues. Your doctor may decide to monitor your drug blood levels more closely if a substitution is made.

If your doctor decides that a generic substitution should NOT be made, be sure that they include “no substitution” on the prescription. This will alert the pharmacist and your insurance company that no generic substitution for the brand should occur.

Bottom Line

This is not all the information you need to know about Lyrica (pregabalin) for safe and effective use. Review the full Lyrica (pregabalin) information here, and discuss this information and any questions with your doctor or other health care provider.

References
  • FDA approves first generics of Lyrica. US Food and Drug Administration (FDA). July 22, 2019. Accessed Nov. 6, 2020 at https://www.fda.gov/news-events/press-announcements/fda-approves-first-generics-lyrica
  • Schachter S, et al. Overview of the management of epilepsy in adults. Up to Date. Accessed Nov. 6, 2020 at https://www.uptodate.com/contents/overview-of-the-management-of-epilepsy-in-adults

Read next

How long does it take for Lyrica to work?

In clinical studies with Lyrica, some patients experienced a decrease in pain as early as the first week, which persisted during the entire study period of 5 to 13 weeks. Continue reading

Does Lyrica cause weight gain?

Weight gain is a common side effect associated with Lyrica treatment. In studies, 9% of Lyrica-treated patients and 2% of placebo-treated patients gained 7% or more compared to their weight at the beginning of the study. Lyrica is also linked with an increase in appetite and fluid retention. Continue reading

How long does Lyrica stay in your system?

Lyrica (pregabalin) will stay in your blood (plasma) for about 35 hours, but its clinical effect may wear off before this time. Studies have shown pregabalin to be detectable in urine for up to 5 to 6 days. Continue reading

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