Has anyone started 50 mg of Pristiq and Then Increased to 100mg because 50mg was no longer working?

I had my pristiq increased to 100 from 50 mg and I was marginally better for a few months. Its been approximately a year and I'm going to switch meds thinking my body is no longer finding sufficient relief. My anxiety is triggered by the least stressful incidents. I wasn't bothered by nausea at all..
Good luck!

I started Pristiq 50mg about 4 years ago then about 5 months in started on 100mg. I have stayed on that dose ever since. I really do feel better in myself and look forward to every day. Pristiq has really been my lifesaver. I don't feel the need to increase the dose. At times during the day I might feel a bit off for a second but that passes. I can see myself being on this medication and dosage very much long term.

I just went from 50 mg of Pristiq to 100 about 3 weeks ago. I still have some depressed days but I have also had days where I felt like myself prior to the recurrence of my depression. I was normal for 17 years on 150 mg of Effexor, then it just stopped working when I hit 50. I am going to stick it out and hope for the best. I have also added Lamictal so we will see. Fortunately, I have not had the nausea, but I feel like it will get better for you. Best wishes.

I have been dealing with anxiety and depression for a very long time im 20 now but it started when i was 15 i started on prozac at 20mg then 40mg . Then i decided it wasnt the right drug for me because i still felt the same then i was on Amitriptyline , and that didnt work at all so ive been on pristiq for over a year now i started at 20mg then 50mg and about 3 days ago i started on 100mg of pristiq and i am very very sleepy and drained i feel like i have no energy . I know that will soon pass and my body is just getting use to it . But ive been soooooo extremely tierd and feeling like im in a daze or a dream . If u want to ask me more questions about my experience with it feel free to call me
This was posted on 11/18/18
My cell is+18432877415

My son was on 50mg for one month and now has started 100mg. So far, so good. No side effects noted. Overall- great medication!

ive only been on 100mg of pristiq for 2 weeks after initial pror 4 wks of 50mg but i find im having severe fatigue sleeping thru the nite aswell as about 4 hrs thru the day and severe indigestion like im having a heart attack im not sure that this is the anti dep for me and sorry i wasnt any help to you but i found nausea increased on the 100mg

A couple of pointers...
Firstly side-effects from Pristiq such as nausea can often occur when a dose is increased but subside as your body adjusts to the new dosage. If you can tolerate the nausea it would be worth persevering with.
Secondly it can take a couple of weeks of taking Pristiq at the increased dosage before you start to feel any positive effects - again worth persevering with.
If you feel you need to reduce your dosage because of the way you are feeling you should see your doctor again.
All the best.