Someone mentioned that in a Gabapentin thread and its got me wondering now.
Are Gabapentin and Lyrica the same base drug?
Question posted by overprescribedagain on 17 April 2013
Last updated on 8 February 2019
Gabapentin and Lyrica or use for the same thing but not the same drug a lot People say that lyrical works better but for me gabapentin is best for me it's really up to your body
Yes I think its considered the same but its effects are different. I take 300 mgs a day and it helps my nerve pain in my arm and ankle.I used to take gabapentin and it also helped but to me the lyrica seems a little stronger than gabapentin.
Anyone got gabapentin? Near Salem Oregon.
I don’t know the answer to my question
Please respond if you do
They are from the same family , gabapentin and
pregabalin except , the lyrica pregabalin make you feel a little drunk if you over take your doze, they make you feel very sleepy, the gabapentin don't have the sleepy effect that's the only difference I found in them, they are brilliant for pain and nerve damage, the lyrica would be best for severe back pain , or any nerve damage, I'm on lyrica 300 mg 3 times a day =900mg
They are different drugs but they are like cousins. Lyrica has one less carbon atom in the molecule. This makes the structure more open. Lyrica is absorbed quicker and longer. However, both gabapentin and pregabalin(Lyrica) work the same way. They attach to a specific sub-unit protien and buffer the calcium ions in the voltage gated calcium channels. This is where nerves are activated.
Both drugs were developed by the same company but pregabalin was invented by a researcher in conjunction with Park-Davis.
I think lyrica and gabapentin are very much the same drug
Yes, Neurontin worked like a miracle for ONE MONTH for me, then I was back to before. My DR at the time, just kept increasing the dosage. I stopped taking it and just recently giving it another try
Lyrica is FDA approved for fybromyalgia, gabapentin is not. Gabapentin is used for several off-label areas such as nerve pain and fibromyalgia. Lyrica is also used for some off-label areas. Drug companies cannot advertise for anything not approved by the FDA, but doctors can still prescribe off-label for other areas. There are some technical differences in how they work. Gabapentin is nonlinear and Lyrica is linear in dose-response relationship. Lyrica dosages are thought to have more predictability in the effect on the body. Gabapentin dosages are thought by some to be more unpredictable in relation to effect. Some think a higher gabapentin dosage may actual have less effect than lower dosages. Being nonlinear, some think gabapentin results vary more from person to person.
Leaning more toward conspiracy theory, some think when Pfizer's patent expired on Neurontin, so a generic gabapentin could be sold, they came up with a "better" option that would make more money than a drug that had a generic competitor. Pfizer was still the sole seller of the generic under their subsidiary Greenstone, but in 2004, Teva in Israel was licensed to sell the generic. In 2004, Lyrica was developed. Some think that coincidence is suspicious. There are valid differences between the two drugs, but some still feel the system is flawed.
No, Gabapentin is just that and lyrica is pregabalin. They are the same type of med but not the same med.
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