Did Cymbalta have any effect on your weight?

Hello group
Today was my first day taking Cymbalta 60 mg for arthritis and for anxiety out and mood stabilizer today I kind of felt a sense of calm already I’m extremely sensitive to medicine before that I was taking Zoloft and my doctor thinks Cymbalta should be much much better so I’m super happy Tim bark on this journey today my appetite was barely there and I felt a little groggy but made it to work and back and have been feeling mellow all day hope this feeling continues everyone wish me luck

Love& greetings from California

I have only been on Cymbalta one day so far. 30mg for major depressive disorder and pain. My Dr is planning to up the dosage in 2wks and again 2wks after that if required.

I was on it many years ago and it caused around 10kg of weight gain quite quickly so I changed to another anto depressant.

All I have noticed this time is some heart palpitations so far. Has anyone else experienced this?

A little weight loss would be appreciated, but as long as it does it's job I'll be happy :)

I have never had any problems with my weight; even after having 5 children. I gained over 80 pounds during the 10+ years I’ve been taking Cymbalta. I also had multiple horrible side effects and I’ve been miserable the whole time. I’ve tapered slowly down to 1 mg and I’m already losing the weight. I no longer look or feel like I’m pregnant. The side effects are finally gone and I’m slowly getting my life back. I can’t wait to be completely off Cymbalta and I will never take another medication like it.

I have been on Cymbalta for fibromyalgia for over 5 years with no weight gain issue.

I was on Cymbalta 14 years. Tried several times to taper off ( but got suicidal) My doctor and I planned a slow 6 month reduction.
I had to get off of it, I gained 53 pounds and never ever gained weight or dieted in my life.
I used a trainer 3 times a week, walked 50 miles a week and never even dropped 1 pound.
The weight caused trouble in my back, and all the crazy exercise damaged my knees and neck. Four surgeries later in a year to correct all the over exercise. I was exhausted ( exerciseing is suppose to help..nope)
I hated myself and my brain just didn’t work right.
It took 6 months, and yes withdrawal even doing slowly, but manageable. My last 20mg was 2 weeks ago.
I was never a foodie person (normal for me before Cymbalta). I eat only healthy fresh food. No meat.
I am hoping to see some weight loss soon. I don’t even recognize myself. My energy is at a high level which I haven’t in years. I still have insomnia but working on that.
Never again. My fibromyalgia will just have to be dealt with in a non drug way.

Hi all,

I've been on cymbalta 30mg for a month now and have lost a stone (14lbs). I would put this down to a complete lack of appetite and daily nausea and diarhea. Don't mind the weight loss though

When I started taking Cymbalta I was a size 6. Now four years later I'm in a 14.

oh yes. when I was on it I gained 20lbs. I was also on prozac at the same time and got serotonin syndrome. it was horrible.

Hi,
I've experienced weight loss with duloxetine (30g 1x day, the smallest dose i guess), 8kg in 6 months and still losing. But then i have history with eating disorders so it's hard to be fully impartial. I don't have the impression that it had an effect on my appetite, but more an enhancement of my metabolism. Daily calories incomes and physical activity hasn't change before/while this treatment. I haven't discuss this with my doctor, being happy with this weight loss and so I don't want him to stop it ( eating disorders saying hello now).

Hi, the name of this drug in the UK is Duloxetine and I have been on it for approximately 6 weeks for nerve pain caused by peripheral neuropathy owing to. 20 yrs of high morning blood sugars caused by diabetes. In the first five weeks the dose has been, 30 mg per day and I have lost 43 lbs in body fat. I have now had the dose increased to 60 mg per day and in the last three days I have lost another 12 lbs. I was huge six weeks ago and I'm happy with the results already esspecially as I cannot excersize very much owing to The fact history of 30 dvts in my legs and five PEs in my lungs. I just don't understand why so many others are gaining weight.

I gained 40-50lbs in 4 months and can't get it off! Stopped taking it about 5 months. It didn't work. Made me more depressed. Wouldn't recommend it!

I have been on cymbalta for a week and I have lost a total of 14lbs I know everybody body is different but this is my experience and I have no appetite nor do I a feeling of hunger

Cymbalta did have a significant impact on my weight; Although, I do have to say it worked the best for my anxiety/ mild depression / OCD. Nothing has worked quite as well.
I gained 40 pounds over the course of 1.5 years, but when taken off of Cymbalta and placed on 20mg of Celexa, I lost 12 lbs in the 1st 3 weeks. To be honest, I contemplate being heavy and happy vs. flat and thinner. I miss the Cymbalta.

Have any of you ever considered that your weight gain was due to something else? Menopause, perhaps?