In the past I have taken both brand name and generic Wellbutrin XL and noticed a significant difference. I've tried to switch from brand name to generic twice in the last couple of years, and both times came to the realization that the generic Wellbutrin/ Bupropion XL is nothing like brand name. But recently my insurance co-pay has gone from $50 to $150, and I'm wondering if anyone has found a generic Wellbutrin XL that feels equivalent to the brand name. Any opinions on what the best generic is?
What is the best generic Wellbutrin?
Question posted by Effect on 11 Feb 2016
Last updated on 9 October 2023
The information on this page reflects personal experiences shared by our community members. It is not reviewed for medical accuracy and should not replace professional medical advice.
41 Answers Page 2
Inactive
24 Feb 2020
Generics are nothing like the name brand Wellbutrin and can put you over the edge. Par Pharm is the worst. sugar pill plus later wanting to end your life. Does nothing good. Its very concussing to believe Dr. FDA when the say the generic for is safe and the same as the name brand. Not true and I don't know how they get away with this betrayal. Name brand is amazing for depression and chronic fatigue buy caution it can cause anxiety.
WildcatVet
13 Jan 2021
I've found that all the generics I've used are equally effective with no side effects. Have been currently been using Par Pharmaceuticals and I have no complaints.
Tbaknits
10 Jan 2020
Has anyone had experience with Alembic pharmaceuticals bupropion 100 mg. It seems stronger or different then Apotex?
NorthwoodsII
7 Nov 2019
I have been taking BuPROpion for several years now. I found that the SANDOZ works the best
for me. My regular pharmacy tried to give a different brand a couple of times. They either did
not work or messed me up. I took them back and requested SANDOZ.
Recently I requested a refill and was told they could no longer get the SANDOZ brand. I ask
them what brand they could provide. I looked them up and saw they were not going to work
for me. They said they had a contract with their supplier and there was nothing they could
do.
I started to have an anxiety attack concerned I would not be able to get SANDOZ anymore.
I have a couple of weeks worth so had some time to look around. I went to 6 different
pharmacies and found 2 that had some in stock. Two that said they could not order it.
and 2 that said they could order it. So I picked the one that was closest to my home and
they ordered it and had it in 3 days. They had to xfer my prescription from my regular
pharamcy.
What a pain. If SANDOZ ever stops making BuPROpion I am in deep trouble.
Does anyone know of other brands that are as good as SANDOZ and still made?
I know that SANDOZ does not work for everyone but seems to be highly regarded
by the people that have responded to this question.
Thanks to all that have responded to this question. It has been very helpfull.
Bill
NorthwoodsII
16 Feb 2020
I need some help people.
I am having trouble getting SANDOZ Bupropion.
Can anyone tell me which available brand is the most like SANDOZ ?
Thanks, Bill
ans123
26 Feb 2020
I'm not sure about a generic brand similar to Sandoz, but I'm in the same boat with Impax/Amneal. The way I've been able to get it over the years when a pharmacy says "we can't get that generic brand" is to ask them "can you order it if I don't use insurance and pay the full price".
Most pharmacies will order it for you if you pay the full price (~100 for generics). The reason they say "they can't get it" is because that's not their current generic (the one they make the most money on), and they assume you will only want the generic that they are willing to accept your insurance for.
Scarlett124
16 Nov 2021
Nov 2021- I just got a Sandoz prescription from CVS for the drug.You can request it from CVS and they will order it. Good luck.
jlring
20 Aug 2019
I cannot take most generic brands of Wellbutrin. They dont work for me at all! The only generic I can take is the Par Pharmaceutical brand which is the same in size and appearance of the Wellbutrin XL brand name medication. The newly approved Lupin brand looks the same so will try that since Par is increasingly more difficult to obtain.
DPatrickFleming
18 Aug 2019
Just be sure the manufacturer is routinely inspected by the FDA. I wouldn't trust drugs from any manufacturing site in India regardless if FDA inspects them. I worked in the pharmaceutical testing industry.
YetAnotherGuy
8 June 2019
With the loss of the Mylan generic, Anyone try the Par Pharmaceuticals generic Bupropion XL? Par was apparently one of the only other generic manufacturers to actually demonstrate bioequivalence with the name brand Wellbutrin XL.
I've been on 150 mg tablets of Bupropion XL, first one, then two after a week. So far no major ill effects from this, and it does seem to be helping. Time will tell. My doc also recently filled a prescription for 300 mg tablets from the same manufacturer, so we'll see how that goes.
YetAnotherGuy
8 June 2019
After looking back, I see a couple of comments about Par... One good, one not so good. While everyone's body is different, I'd be curious to hear more about this. At one point Par and Mylan were the only ones to demonstrate 100% bioequivalence with the name brand.
YetAnotherGuy
8 June 2019
After looking back, I see a couple of comments about Par... One good, one not so good. While everyone's body is different, I'd be curious to hear more about this. At one point Par and Mylan were the only ones to demonstrate 100% bioequivalence with the name brand.
bluesinthenight
8 June 2019
Mylan has discontinued making their SR version of bupropion, but they have resumed making immediate release - though that's not what they call it. It's just called Mylan Bupropion and comes in 100mg tablets. Having had success with Mylan SR for years and abysmal results with other generics, I decided to try Mylan's immediate release formula. I've been on it over a month now, and I can tell virtually no difference from the sustained release and, more importantly, no awful side effects. Yes, the immediate release formula kicks in a little faster and wears off a little faster, but it's not a roller coaster high and then crashing the way I've experienced with other bupropion generics that were supposed to be sustained release. Taking the regular Mylan bupropion enables me to take my second dose in the early afternoon and I'm able to get to sleep earlier, which is definitely a plus.
I called Mylan, and they told me that they would resume manufacturing the XL version of bupropion in August, 2019, but I'm going to stick with the regular release bupropion. At least one other person on this thread has made the switch to Mylan immediate release and is happy with the results as am I.
WildcatVet
12 Jan 2021
I've had a couple of others that all seemed the same to me but more often than not I get Par Pharmaceuticals. Very effective with no side effects. :)
YetAnotherGuy
13 Feb 2023
My doc eventually started writing my prescriptions as "name brand only" due to the inconsistencies and my bad reactions to the various generics. I never knew which generic I would get. It varied by pharmacy, and could even vary month to month. It took me a LONG time to realize what was going on. It took me even longer to figure out how to use the manufacturer's co-pay assistance card to bring down the $$$$ cost (not paid by insurance) down to about $5. Oddly, I cannot use those discount cards in California. My solution? Get my first fills out of the state until I reach my deductible. It's a bizarre system. Even though I only pay $5 when using the manufacturer's copay assistance card, it still applies the full cost to my deductible. I hate insurance and drug companies... :-(
GoldenHours
21 April 2019
I've been on Mylan (apparently hard to find these days, if they even make it anymore) and Sandoz bupropion. After 6 years I just got back on bupropion and the generic I got was "ScieGen". I had never heard of this one and it must be newer but it was so bad I couldn't stand it and stopped after 6 days.
The agitated feeling that ScieGen gave me was terrible. Back on Sandoz now after I called around to find it. Sandoz is a generally well tolerated generic from the feedback I see from people online. And I can tell you it feels noticeably more gentle to me.
Wellbutrin_111
20 April 2019
Attention!! Mylan Brand Wellbutrin Has been discontinued. I personally take the 150SR, I’ve tried the brand as well as a couple of other generics and none of them work for me. I am putting together a petition online to send to Mylan. I am also paying for a RADIO COMMERCIAL lthat will be played during the Ben Shapiro show as well as others on a Philadelphia radio station (Fox 1180) urging people to call whatever number I am able to get. I have no animosity towards the company ( no lawsuits etc.). I’m sure it was just a business decision but they need to know that a lot of people are depending on that specific medication. If you read this and are willing to help in one way or another even if it’s just signing the petition please let me know as long as at least one person gets back to me I will supply some form of contact information. Of course I am staying anonymous personally. PLEASE HELP, WE CAN DO THIS!!!
WildcatVet
21 April 2019
It was discontinued in June, 2018.
Mylan Pharmaceuticals, Inc.
Company Contact Information:
800-796-9526
Wellbutrin_111
21 April 2019
Thanks for getting back to me, I’m going to get to the CEO/whoever else makes these decisions. My doctor will be writing the letter as well as presenting the petition that will be online that I will hopefully be able to give you a link to or whatever. I know there’s no guarantees here but with social media and “popular demand“ a company would do it even just for PR or if they just do one or two strengths maybe it won’t be that big of a financial loser if it ever was to begin with. Like I said no guarantees but I don’t care if I have to literally purchase a billboard or already going on the radio. Why would I spend this much money on it? Anyone who suffers with depression will definitely understand. I need others involved though. Money would be great but even more important is just having numbers of people. If somebody would like to set up a Facebook page regarding this, that would be great. Twitter seems to be best but Mylan Isn’t on it.
Perhaps there’s a division or at least some people that could be tagged or whatever you call it on a Twitter post. Any thoughts? Any help offers?
bluesinthenight
22 April 2019
I spoke with Mylan a few weeks ago and again today. They reaffirmed that they have discontinued ONLY the SR (sustained release) version of Bupropion, but have already resumed making the IR (immediate release - 100mg) and will resume manufacturing XL (extended release - both 150mg and 300mg) in August 2019. One of their manufacturing plants was shut down for awhile (something I found out on my own - they didn't inform me of this), and I'm guessing that had something to do with the fact that they have been making no Bupropion at all since June of 2018. I have been taking Mylan Bupropion SR for many years, and I tried several other generics with dismal results. I had my doctor write a prescription for the immediate release Mylan Bupropion. I had no trouble getting it filled. I checked the ingredients of the Mylan SR against those of the Mylan IR and they are almost identical. I assume the difference has to do with the sustained release of the SR version.
If you look up the Wellbutrin release graph, you will see that that the IR peaks in the first hour and valleys at 6 hours, the SR peaks at about 2-3 hours and valleys at around 10 hours, and the XL peaks at about 5-6 hours and valleys at about 18-24 hours. I haven't started taking the immediate release, but when I do, I realize that I will have to time my dosages differently. I have read studies (controlled) in which patients were switched from sustained release Bupropion to immediate release without incident. I'm hoping that the unfortunate side effects that I've experienced with other generics won't happen since it's still a Mylan product and the ingredients virtually the same. I had some problems with Sandoz, but it seems that of the others available out there, Sandoz is a good alternative for most people. I have family members who take Sandoz with good results and without any problems. I'm very hopeful that the Mylan Immediate Release will work for me and will report my results when I have been on it long enough to see how it's working. So for those of you who take Mylan Extended Release, take heart. They are going to start making it again.
noroozis
18 Feb 2019
I started with Cipla and felt amazing. I hadn't had any anxiety attacks or self-harm desires since starting it. Then last spring the pharmacy changed me to Lupin and I started feeling the familiar anti-depressant adjustment symptoms. They're milder for me with Wellbutrin than SSRI/SNRI based ones but still very specific body aches/inflammation. Also gave me intense fatigue, anxiety and agitation. After reading this thread I finally found a local pharmacy that agreed to get Mylan in stock just for me. I could tell it made a difference because yet again I had adjustment symptoms. This time it was for the better though. I stuck with that until I moved to a different state. It wasn't as amazing as Cipla but at least it was good and stable. I was able to get CVS to give me Cipla like I started out with and I have been back on that for 5 months now.
We recently had a snow storm so I couldn't drive out to the CVS and decided to refill my prescription at a closer pharmacy I could walk to. I totally forgot about requesting a specific manufacturer and just picked up what they gave me. They gave me Pars pharmaceuticals. Within 2 days I noticed an unusually intense anxiety, agitation and fatigue. So far Cipla and Mylan have been the best for me. I think I tried Sandoz once but in Instant Release for only a few weeks until being changed to Extended Release so I can't really say. Is there a safe and affordable way to get the brand name from Canada? Could one take a written prescription to Canada and just fill it out there?
Smiling-again
19 Jan 2019
Bad news. MYLAN IS NO LONGER GOING TO BE MANUFACTURING BUPROPION. Whether or not they will be manufacturing Zyban (same drug but used for patients to quit smoking) is unknown to me.
You can go to their website and email them and ask for yourself if you want to double-check my information. I heard it first through my pharmacy, and decided to check with Mylan for myself.
I suspect it's the "real" Wellbutrin and they are discontinuing it because... well I have some guesses, but they're probably all wrong. Mylan purchased Glaxo-Smith-Kline and GSK were the original makers of Wellbutrin... so maybe Mylan got the original recipe and... I don't know... politics, contracts, and money play a role. Just guessing.
bluesinthenight
19 Jan 2019
I found out about the Mylan discontinuation of bupropion last summer (2018). I, too, phoned Mylan to confirm it. It's also listed on the FDA drug shortages list as "discontinued" manufacturing as of June 2018 - for "business reasons". At the time, I had no idea how difficult it was going to be to find an alternative.
Smiling-again
17 Feb 2019
Mylan will still be manufacturing the 100 mg immediate release AND the 300 mg XL. In my experience the Mylan brand 300 mg XL does not work but the 100 mg Mylan brand seems to work. I have had no luck with any other generic working and have lost months to depression because I can't afford Wellbutrin brand name. I literally spend my days in bed all day. It is NO life for anyone. I wish the FDA was aware of how much the generic Wellburtin negatively affects people. But they probably don't care or they would do more about it.
bluesinthenight
18 Feb 2019
Sort of good news: I just got off the phone with Mylan. They WILL be making 100IR (immediate release) tablets again, and they will be available in April 2019. They will resume making 150XL & 300XL, but these will not be available until August 2019. They are NOT going to resume making any SR version (which is what I take). If all else fails, I'll try the immediate release, though timing it will require diligence on my part, and/or the XL when it becomes available. I know that Mylan has not worked for everyone, but it has for many. I was hoping Sandoz would do it, but the constipation was more than I could tolerate. I'm still thinking of getting my doctor to go for the brand name with the insurance company.
Smiling-again
19 Feb 2019
****. Even if you don't use Mylan brand or even if you hate it please read my second paragraph!! ***
GOOD NEWS my fellow Wellbutrin users! I think I may be onto something! I switched to Mylan 100 mg and it's working even better than the Mylan 150 SR! Mylan is NOT discontinuing the production of their 100 mg pill.
Mylan is still manufacturing this and it's NOT on back order and I have had GREAT luck with it. Better than the 150 SR! I take two in the morning and two in the evening (total of 400 mg). This makes me wonder if ALL OF THE GENERICS WOULD WORK like the brand name if you take take them as I do.
If you are living in bed and miserable because your generic isn't working, please ask you doctor to prescribe the 100 mg pill and see if you can take two in the morning and one at night (300 mg total) or two in the morning and two at night (400 mg total). I would LOVE to hear from you if you tried this and had success. For me it took about three days to kick in. I had been on a crappy generics 150SR before I started the 100 regime.
****. Also, please feel free to copy and paste this to other Wellbutrin chats or clubs or wherever you want. I would love for all of us to get better and these generic SRs and XLs don't seem to be working. Please try it and let the rest of us know. You could save a life!
bluesinthenight
19 Feb 2019
Hey, Smiling! This is great news. I'm going to try the Mylan 100 immediate release when I can no longer get the SR. I'm really glad to hear it's working for you. It gives me hope. I've been in turmoil since I found out the Mylan SR was discontinued and the other generics I've tried haven't worked out for me at all. Glad to hear your endorsement of the IR.
Smiling-again
19 Feb 2019
Hey bluesinthenight ! I hope and pray that the 100 mg 3 or 4 times a day works for everyone who suffers from this insidious condition. For everyone that has tried manufacturer after manufacturer after manufacturer!
I forgot to mention that I don't know if the 100 mg immediate release is called 100 mg IR... or just 100 mg (without the IR). I have seen it written both ways but I think it's the same thing.
Best of luck to all of us. There is hope with this method. I believe it!
SavageBotanist
19 Jan 2019
Wellbutrin XL Brand is manufactured by Valiant- they had a patent on the medication AND -the coating- separately. The patent on the medication went up first so generics came out but the patent on the coating for WELLBUTRIN XL did not end until this year. I have hopes that generics will be getting the coating too. This has been a nightmare for years for me and my partner. They should not be allowed to patent a coating THAT MAKES THE MEDICATION WORK RIGHT separately from the medicine inside. These are people’s brain chemistry they’re messing with and they don’t care. I went on Lupin a couple months ago and I’m starting to wonder if it’s not making me reactionary and weepy. My partner could only take the brand name and we were paying 100$ a month for it but they changed their program again and if your Insurance won’t pay for even a portion of it you can’t use valiant manufacturer coupon.
We can not afford 1800$ a month for a prescription so he had to try generic and he went on the Lupin too and started being weepy too and I’m not sure what to think anymore.
GKNY
10 Jan 2019
Good Luck on your search to find the best generic that works for you. Been there, done that. Unfortunately, all Pharmaceuticals want a piece of the "anti-depressive" market as a revenue stream. This explains why so many bupropion generics are available, and the list continues to grow at a rapid pace. With that said, it'll be difficult to find the one true generic that provides equivalent effectiveness (to each individual or particularly you) as the brand name. The cost of brand name continues to increase. There is no known generic considered to be as universally effective. Local pharmacies choice of generics is driven by the bottom line. Therefore, they do not stock generics based on a scientific measurement of effectiveness, but the least expensive. Most Pharmacies here issue Anchen Par brand generic as it known to be among the least expensive on the market (and as far as I'm concerned, and as others on this blog has pointed out, ineffectual).
I too searched for the most suitable antidepressant. Mylan, Lupin, Watson, jubilant, etc. cannot be found here. I've been taking Actavis generic on a consistent for some time now. However, I have to special request it. It's ok. However, I don't know if it continues to benefit me or if I'm just living a better life; thinking better thoughts; caring less of what people think of me (a trigger), managing seemingly negative situations, and appreciating my self-worth.
bluesinthenight
10 Jan 2019
Since Actavis bought Watson, Watson no longer really exists. It's hard to say whether Actavis is using the Watson formula or another formula. Actavis seems to work for some people. It didn't work well for me. Sandoz is a good alternative for most people, though you do have to special request it or your doctor has to write "Dispense as Written" for Sandoz on the prescription. Pharmacies don't stock it because it's more expensive, and, as you say, it's all about the bottom line. I've been trying varying generics since I found out that Mylan was no longer making bupropion in any form. I've been taking it for many years successfully, but my stash will run out and I have to find another generic bupropion I can tolerate. Sandoz was good in many respects, but I'm on a high dose (400mg SR) and had side effects that caused me to eventually go back to Mylan. Guess the next thing is to have my doctor request the brand name. I don't know how hard my insurance company will fight it. In the meantime, I'm in limbo...
stopchangingmymeds
12 Jan 2019
Good luck to you. I'm getting ready to find out what I will be able to get instead of the Mylan. The constipation comments about the Sandoz worry me. I had severe constipation on the Watson XL, but it worked great otherwise and I don't want to go back to that. I have virtually zero side effects with Mylan other than it helps the depression. It is so frustrating that we have to continually go through this each month just to feel ok!
bluesinthenight
12 Jan 2019
Sandoz is worth a try. Everyone is different. I had severe constipation with Sandoz on 400mg SR. It also cranked up my tinnitus and caused me a some nausea. I have a relative who takes 200mg SR of Sandoz a day and has none of these problems. I'm going to have to see if I can get brand name through my insurance company. My doctor is prepared to run the gauntlet for me. But I'm afraid now that I'll have problems even with the brand name. After reading a number of threads, I wonder if the time release mechanism has something to do with the constipation issues some have had on various generics. I'm prepared to try IR (Immediate Release) if I continue to have problems, but timing it precisely every day will be a pain. I've been back on Mylan for 3 weeks and am still having problems. I hope it'll get better.
I was on Sandoz for a month and thought it was going pretty well, aside from some tinnitus and nausea - but at exactly one month on it, the constipation hit. I didn't want to believe it was the Sandoz, because I thought I'd found the alternative to Mylan. I finally had to admit it was the Sandoz.
Bob_FL
9 May 2019
Update: 5/8/19 - After trying Sandoz for awhile - it stopped working for me. Unfortuantely, there is no Sandoz XR version. In fact, Sandoz "slow release - SR" is a big change from "extended release XR." With SR the medicine is released much faster, and there is an initial rush which wears off after approx. 12 hours (for me anyway). In my view, the Valeant Canadian brand is the best bet (from a reputable Canadian pharmacy) - or - of course the US brand which is unbelievably expensive. Another alternative is to have your doctor increase the dosage to generic 450mg and you'll be getting 80% of that amount as per the FDA. You have to try different approaches with this one!
Doxiemom001
10 Jan 2019
I've only tried generic. I was started on
150mg mfg by Lupin and had to drop it because of excessive hair loss after 3 months. This is the only medicine that has helped me, so I tried 75mg mfg by Heritage, in hopes that the lower dose would stop or slow down the hair loss. Symptom never subsided so I came off bupropion all together. I'm desperately seeking a way to get around the hair loss so I can go back on the meds. Wondering if brand name would still give me the same symptom.
camaffucci
4 Dec 2018
I started taking Bupropion XL 150mg 24hr about 3 months ago and have gotten a different generic manufacturer from my pharmacy each month. First Actavis, then Lupin and now PAR. Actavis seemed to work best for me, but it also may have been that I felt the most effect from it because I was starting from 0. Lupin felt like I was back at 0 and PAR seems a bit better, but not much.
I called my pharmacy today to see which manufacturer they have available so I could do some research before refilling. Turns out they have two completely different manufacturers available now - IMPAX and Accord - neither of which I’m able to find much on in the way of reviews. Does anyone have experience with either of these? TIA.
medsadventurer
21 Dec 2019
Out of generics, I tried Actavis and Lupin. Actavis works ok but has ups and downs during the day. I was switched by pharmacy to Lupin felt like a sugar pill and relapsed quickly. I'm looking to get brand next to see if it's better than any generic.
rldunn44
3 Dec 2020
Actavis worked great for me (very few side effects) but Accord makes me sick as a dog (it tears up my stomach, makes me dizzy, and my heart race). From research, it seems everyone has a slightly different reaction to each generic. What works well for one person does not work for another. I wish the generics did not vary so much because getting one particular manufacturer can be tough. Pharmacies tend to switch to whatever is cheapest. I am having to try to switch off the XL to the regular because my pharmacy has no Actavis in stock and tells me it is on backorder. I tried to switch to the Accord version again and am sick as a dog. I feel like my doctor and pharmacist don't believe me when I tell them there is such a big difference but they both try to accommodate me anyway. I am hoping the regular version works for me because I absolutely can not take the one manufactured by Accord.
leesochka
14 Nov 2018
Just thought I should add my experience here! One random generic gave me a slight allergic reaction. That's when I stopped taking it and researched different generics. People said good things about Mylan and Sandoz. So I tried both!
My prescription is 100 SR (once a day for me). With the Mylan, I almost felt no effect. No good stuff and no bad stuff. Pretty underwhelming. With Sandoz, my depression is very noticeably lifted! It can feel like a miracle sometimes. I'm still around 6 weeks in. I recently started to get anxiety from the Sandoz, so I switched to Mylan for a few days to let my brain chill out. I'm back on Sandoz now and am feeling great so far!
I'm thinking of trying out different generics to see which one works best for me. If I could avoid the occasional anxiety, that would be ideal. I'm thinking of trying Watson next.
For anyone that feels like giving up after one bad experience with a generic: keep trying! It was a bit discouraging for me at first but I found something that almost completely silences the horrible bully in my brain. It gives color and energy to my life. Don't give up - the right med (or combination of meds) is out there for you!
Camibata
17 Nov 2018
I was taking the Mylan SR for almost a year when the pharmacy recently started changing manufacturers. The first time they let me know and were able to get me one final month of Mylan before totally discontinued. The next month they gave me Dr Reddys and I can’t remember how I felt to be honest because all I remember is they switched me again the next month to Solco and It was horrible.l was a mess. The month after that is when I spoke up and said no way!! 3 months in a row changing. This time the brand was Sandoz and that Mylan was totally gone. I said anything as long as not the Solco. Felt great on the Sandoz. I think I like it better then the Mylan!! Pharmacist agreed Solco is junk. Everyone complains. Went back the other day and they changed AGAIN!!! Now back to Dr Reddys. So upset. They had about a 1/2 months worth of Sandoz available and then the next bottle was Solco. What the heck??? So I’m gonna try the Dr Reddys again - have a few days left of Sandoz.
Has anyone recently taken the Dr Reddys? I’d like to try to find out where I can get the Sandoz. Pharmacy said the company goes with whatever is cheapest for them that month??? Should I try a different pharmacy or try the mail order route? If so, can we request manufacturers in mail order?? Here come the holidays and I’m nervous about switching again!
stopchangingmymeds
16 Dec 2018
Years ago I took Bupropion XL by Watson, it was great, tons of energy, lost weight, no more depression. Then they took it off the market and it was a slow downhill spiral of messing with my brain every month until I switched to brand, but I think that was after the brand was made by Valeant. Anyway, it was ok, but not great, nothing worked like Watson. So I went off of all drugs and was depression free for a few years. Gradually it started to come back and in the meantime my insurance will not cover brand at all. So I reluctantly tried generic XL by Par. It was not great, didn't help much with depression and I could feel it dump into my system about 90 minutes in and that felt awful. Oddly, the best generic besides Watson in the past had been Par, it obviously changed.
In october I started on the SR 150MG by Mylan. It was very hard to find and of course it is working great and now I've discovered it is discontinued so I won't be able to get it anymore.
There was a comment in this thread about trying Watson again?? Is that back? When I called around the major pharmacies were carrying Dr. Reddy's and some Actavis. If I recall Actavis was horrible for me in the past. I haven't called to see what SR's are carried.
Anyone switched from Mylan working well to something else that is working well?
bluesinthenight
22 Dec 2018
Watson SR is out there, but I don't know if they are making an XL version. The sustained release mechanism of the Watson SR didn't work well for me. It took me up very quickly (not a bad sensation, really), but it also dropped me quickly and hard. I'd be dropping off to sleep in the afternoon. I could've worked with the timing (I was taking a split dose of 200 in the morning & 200 in the afternoon), but I found myself becoming increasingly depressed and anxious. I went back on Mylan temporarily, knowing I'd have to find something to replace it. I thought I'd found it in Sandoz. Sandoz kept me even psychologically, but eventually the side effects became intolerable. I could deal with the nausea and the increase in my tinnitus, but the crippling constipation finally did me in. I gave Sandoz a 3 month trial. The constipation didn't start until one month after I started taking it. Some of my problems could have had to do with the high dose I take.
A lot of people like Sandoz, and had I not had the physical side effects, I would've been happy with it. I'm now back on Mylan and looking for another to replace it. I thought I'd try Torrent next, as it seems to have few inactive ingredients and they seem most similar to Mylan, which has worked best for me. I'll be waiting to stabilize on Mylan for a month or 2 before I try it, though. Good luck to everyone trying to find a generic bupropion that works for them. Find it and have your doctor write a prescription for that particular generic.
Related topics
wellbutrin, wellbutrin xl, depression, bupropion
Further information
Similar questions
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.