... name working so much better than generic. Brand name is very expensive and my insurance doesn't cover it. Does anyone have experience using generic vs brand name. Has generic worked for anyone??
Depression - I'm taking generic Wellbutrin (bupropion 150 mg xl).. I've read so much about brand?
Question posted by sara301 on 18 Aug 2016
Last updated on 19 October 2018
Yes Generic works! If you start off with Generic there shouldn't be any problems. I've taken both. Some people say when they start out with the Brand name that then switching to generic doesn't work as well for them. They usually want to go back to brand name. They complain about it not being as strong?! So if you start out with Generic it shouldn't be a problem. It didn't affect me like that, but I wasn't on the brand very long. Give it a try?! I hope it works for you. Just don't worry so much about, you'll be okay. Give me an update.. Let me know how it goes.
I had just started back on brand Wellbutrin..doc gave me samples for 5 weeks to build up to the correct dose. This is my miracle! Had taken it 5-6 years ago and had to stop after losing insurance coverage..come to find out my current insurance will not cover brand. Bupropion makes me crazy!! I have been on it for a week and i am so agitated and on edge..I feel like I am back to square one. The mnfg. company is Actavis... anyone have any experience?? I know my body and there absolutely is a difference!!! I tried the generic years ago as well and had the same reaction..or no reaction...
So I've been taking bupropion 150xl from global pharmaceuticals for 2 weeks. I noticed more energy, less appetite. Thought I was feeling better, than it stopped so I went up to 300 mg xl from teva, it's been 4 days. I don't feel energy, I'm emotional, crying a lot. My social anxiety is still bad. I don't know if I should change antidepressants.. I was on lexapro a few years ago, it seemed to help a little but after a couple of years, it stopped working. Maybe it's the generic Teva that's not working for me. Idk... I see my psych doc on the 6th so hopefully he can give me some answers. Its just frustrating. Sometimes I don't know what I'm feeling.
There is no way I can take the generic Wellbutrin! The difference is as great as day and night. If you have not taken the brand Wellbutrin, I can understand your questioning to the effectiveness of the generic.
I had always been on brand, changed doctors, put on generic Wellbutrin, made a nose dive downwards in mood and anxiety. It was horrible. After 3 months, asked for brand, fought with insurance, finally won and wow, there was a huge difference between the brand and generic!
Every year it is redundant with insurance, fighting for special coverage, dealing with an inefficient doctor's office staff. However, it is worth every hour I spend.
If you don't feel like you are doing better, please check with your insurance to see what is required for a doctor to specify brand before seeing your doctor next time. It never hurts to ask questions and be in the know. Wellbutrin should give you energy. If I recall, it takes about three weeks for it to get into your system to be effective. Good luck.
I immediately identified with your experience. Then I was surprised by some of the answers you received indicating that the generic forms worked for them.
I have continued on the brand for several years since having the experience of feeling so much worse when my insurance plan switched me to bupropion. My doctor told me that he was not surprised at my reaction as he knew from the literature that others were having this problem. It took perseverance to get back on the brand, but he was able to convince the company to dispense as written, that is, only with the brand. (I don't know whether the dosage has anything to do with it or not. I'm now taking 450mg a day.) The copay was a lot more, but I have been able to pay it and believe that my ability to function as a normal human is worth it.
Now I am questioning that decision, but I dread having another negative reaction.
I certainly wish you the best in finding relief, and I completely sympathize with your situation.
The difference between brand and generic in actuality is in the binders and preservatives and the manufacturer must show that no significant difference in the rate and extent it absorbs into the body, the FDA did a study and found the difference in effectiveness to be on average 3 1/2%, essentially no difference with the exception of expiration dates can differ greatly. Some drugs have such a small window of therapeutic and toxic that 3 1/2% can make a big difference but Wellbutrin and to my knowledge no antidepressants fall into that category. People who say they can tell the difference are telling the truth but its a psychological thing. Ask your pharmacist and I'm willing to bet you will get the same response
I've just started the Wellbutrin SR generic at 100mg and I'm liking it, I'm so sensitive with immediate side effects and none yet 5 days into it plus weight loss is a help which I can use after weight put on from Vybrid! It says decreased appetite, I do have that and liking it! Hope this helps, bests to you!
Hey there, I'm having the same issue. I'm being tapered of of zoloft right now, and am supposed to start bupropion xl in a week or so. There is no way I could ever afford the brand name, and same as you, my insurance doesn't cover it. I've read better things about the brand name, so it's stressing me out a little bit. What brand generic are you taking? Let me know how your experience goes! Wishing the best.
I took the generic for years and it worked just as well ~ or better ~ than the brand.
Good luck to you!
I was on Wellbutrin but didn't provide any relief but good part was no side effects.
I've never had any relief with antidepressants.
I did want to tell you about Ritalin. I checked the forums and it's a common complaint about generics
The generics have to be of the same chemical structure as the original. It is mandatory to be issued a license to distribute the generic equivalent. This is not inexpensive !
One trick the formulators use is to "tweak" the chemical structure prior to patent expiration to make it "better". If the FDA approves it then the drug remains under the original company for many years which adds up to huge amounts of money.
The generics get ready to apply for distribution but this tactic changes everything.
If anyone can explain the politics I'd appreciate hearing from you.
I think the feeling that you are describing is the coating (or lack of) that changes its consistency.
Ritalin seemed to last longer with its positive effects.
Methylphenidate (Ritalin) generic disintegrates in my pill bottle by the end of the month. It feels cheaper to touch and is affected just by the moisture of my hands.
It makes sense to me that the absorption rate is changed just enough to make me tell the med is not the same or as good.
I know it is the same chemicals but it's different !
I also can tell which generic is better than another.
I know there are pharmacists on this site who offer great advice.
Perhaps they could answer this question because I've not been able to get an answer when I've picked them up from the pharmacy. They say my observations are interesting but it is the same drug.
If there are any pharmacists reading ...
Is it the med COATING that can make the difference ?
I know enteric coated drugs won't break apart just by handling them plus they are better on the lining of the stomach.
Why isn't that part also mandated by the FDA to be the same as the original formulation ?
Hi Sara: I took brand name Wellbutrin SR for years. Then I was switched to generic bupropion SR. The different generic ones work differently, with varied effectiveness, as well as varied side effects. So you might have to try a couple to see which one works best for you. I tried a couple years ago to go back to brand name for efficacy, but was surprised and disappointed that it no longer worked the way it did in previous years. So I stuck with one of the generic ones and it worked just fine. The cost for brand name is astronomical these days, which is ridiculous that the pharmaceutical companies can get away with this! G
Yes, I've taken both and it works relatively the same. My daughter has taken both and says it works exactly the same. I started out with the brand name and switched to the generic. I think she started out with the generic. It really has been an uplift for me with depression and helps some with anxiety & panic. Doesn't take care of it all completely, but makes a tremendous difference. My daughter has been more so satisfied with it than I. It's more of a daytime antidepressant to me. My daughter prefers taking it at night. I have "insomnia"so I need an antidepressant that helps with sleep as well as my depression, anxiety/panic. For any smokers out there, Willbutin also does Well with helping to curve your appetite for smoking. It works if you aloud it to work. Neither one of Us have experienced any serious or bothersome side affects. I think she mentioned a little bit of a dry mouth, only.
I'll double check with her?! Just don't forget.. taking these "meds" are and or can be different for each of Us. Wishing you well ... god bless
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