Everything was going really well and I felt better than ever,for the first two wks on 145 and have been on the 290 for four days. Nothing for two days except stomach distension. I am so disappointed beyond belief, I will take the 145 for a month and give it a fair shot.
would you please clarify your question 1) indications for taking meds 2) how did the effect change on the higher dosage? 3) why was your dose lowered 4) have you notified your doctor about your concerns, if not please inform your doctor immediately?
Madhup Joshi, MD
Yes!!! This exact thing happened, is happening to me... Down to the four days of constipation. I broke down and took a laxative. The lower dose worked for two weeks, a bowl movement every day! Then it just stopped. So, my doctor put me on the higher dose and I felt like a hot air balloon and was still constipated. I've been trying linzess for almost a month now and was so hopeful, but I think I'm done. Why take it, if it isn't going to work. Plus seeing the exact same thing happen to you convinces me this is not good.
Yes! I have been on Linzess for one month and it works one day a week within 2 hours of taking it on an empty stomach. The remainder of the week I am constipated, full of gas, bloated, and have cramps. I am glad that it only cost me $20/month, but it is a waste of money so far.
This just started happening to me. I actually took it every 3 or 4 days for a year and then it just stopped working. Desperate, I tried one dose of Miralax with the Linzess pill. The following day it worked.
If I just take Miralax once a day, that doesn't work, but perhaps the combination will.
I am so glad I found you guys!! I have been on linzess 145 for about 3 months it was working great. Now it's been several days since I've been able to go. I upped my dose to 290 a few days ago still nothing. I honestly don't think I can go back to the high doses of magnesium citrate or milk of magnesia. I have taken so much of that stuff my tolerance is very high and makes me sick to my stomach when I take it. There has got to be a better way!!
I have had constipation problems most of my adult life. I took various stool softeners and laxatives for years but constipation seemed to get worse with age. I was given linzess a try and initially I had explosive diarrhea after only an hour or so after taking it. Slowly, by working with dosage it seemed to get better, but now about a month later the pill stopped working and I experienced the same frustration as others in this forum. I am thinking I will need to add a dose of laxative to get some kind of relief. According to the symptoms, I am 72 and I have CIC. What to do???
This did happen to me on 145., however it started working again after I began taking it every three or 4 days.
It seemed to work better when I had more buildup. Of course my body, since childhood has never been a once a day body. So perhaps not every day would work better. On the days I take it I try to have a very light schedule because I am never sure exactly what is going to happen. There are still some days nothing happens and I begin to worry, but the following pill works just fine.
I have been taking the 145 daily for almost 5 months. I have days when it works almost instantly and days when it doesn't work at all. My doctor also prescribed two OTC stool softeners to coincide with the Linzess. I take the stool softeners at night to help so that I'm not taking a handful of pills in the morning. The Linzess is more than enough some days. I'm not sure if diet or lifestyle affects the Linzess and is what causes it not to work some days. I would suggest talking to your doctor to see if something like a stool softener could help supplement the Linzess. I know what works for one may not work for others.
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