I have a very pleasant experience taking 50 mg amitryptilline at the start of an intercontinental airflight. I did several hundres flights, but never succeeded in sleeping, not even in business class, until I took a single dose of 50 mg amitryptilline. I slept wonderfully and awoke without any hangover. Now somebody is warning me that I have to be careful doing this, because amitriptiline may have psychotic effects. Is their any evidence that a single 50 mg dose may have such an effect?

Thanks in advance for your advice

Louis Harmsen, the Netherlands