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Candesartan Side Effects

Not all side effects for candesartan may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to candesartan: oral tablet

In addition to its needed effects, some unwanted effects may be caused by candesartan. In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking candesartan:

Rare
  • Arm, back, or jaw pain
  • bleeding gums
  • chest pain or discomfort
  • chest tightness or heaviness
  • chills
  • cough or hoarseness
  • dizziness
  • fainting
  • fast or irregular heartbeat
  • fever
  • joint pain
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • lightheadedness
  • lower back or side pain
  • nausea
  • nosebleeds
  • pain or discomfort in the arms, jaw, back, or neck
  • painful or difficult urination
  • shortness of breath
  • sweating
  • swelling of the feet or lower legs
  • vomiting
Incidence not known
  • Abdominal or stomach pain
  • black, tarry stools
  • bloody urine
  • coma
  • confusion
  • convulsions
  • dark urine
  • decreased urine output
  • difficult or troubled breathing
  • general feeling of tiredness or weakness
  • headache
  • hives or welts
  • increased blood pressure
  • increased thirst
  • itching
  • light-colored stools
  • loss of appetite
  • muscle pain or cramps
  • nervousness
  • numbness or tingling in the hands, feet, or lips
  • pale skin
  • redness of the skin
  • skin rash
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swelling of the face, ankles, or hands
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • upper right abdominal or stomach pain
  • weakness or heaviness of the legs
  • weight gain
  • yellow eyes or skin

Some of the side effects that can occur with candesartan may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common
  • Ear congestion or pain
  • head congestion
  • runny or stuffy nose
  • sneezing

For Healthcare Professionals

Applies to candesartan: oral tablet

General

The most common side effects were upper respiratory tract infection, dizziness, back pain, pharyngitis, and rhinitis.[Ref]

Respiratory

Common (1% to 10%): Upper respiratory tract infection, pharyngitis, rhinitis, nasopharyngitis
Very rare (less than 0.01%): Cough[Ref]

Renal

Common (1% to 10%): Renal impairment, creatinine increased, urea increased[Ref]

Nervous system

Common (1% to 10%): Dizziness, headache
Very rare (less than 0.01%): Somnolence[Ref]

Cardiovascular

Common (1% to 10%): Hypotension, sinus arrhythmia
Very rare (less than 0.01%): Palpitations[Ref]

Hepatic

Common (1% to 10%): ALT increased
Uncommon (0.1% to 1%): Abnormal liver function, AST increased
Very rare (less than 0.01%): Hepatitis[Ref]

Metabolic

Common (1% to 10%): Hyperkalemia
Uncommon (0.1% to 1%): Hyponatremia[Ref]

Musculoskeletal

Common (1% to 10%): Back pain
Very rare (less than 0.01%): Arthralgia, myalgia
Frequency not reported: Rhabdomyolysis[Ref]

Dermatologic

Common (1% to 10%): Rash
Very rare (less than 0.01%): Pruritus, urticaria[Ref]

Other

Common (1% to 10%): Pyrexia[Ref]

Psychiatric

Very rare (less than 0.01%): Agitation, anxiety, depression, insomnia, nervousness, nightmare, sleep disorder[Ref]

Hematologic

Very rare (less than 0.01%): Neutropenia, leukopenia, agranulocytosis[Ref]

Gastrointestinal

Very rare (less than 0.01%): Nausea
Frequency not reported: Oropharyngeal pain[Ref]

Immunologic

Very rare (less than 0.01%): Angioedema[Ref]

References

1. "Product Information. Atacand (candesartan)." Astra Pharmaceuticals, Wayne, PA.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. Cerner Multum, Inc. "Australian Product Information." O 0

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