Angiotensin II inhibitors

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Angiotensin II is an extremely potent vasoconstrictor. It also increases release of noradrenaline, reinforcing vasoconstriction and increases the heart rate and force of contraction.

It increases re-absorption of sodium ions by the kidneys and stimulates secretion of aldosterone from the adrenal cortex. Aldosterone further increases sodium re-absorption and water retention by the kidneys.

Angiotensin II inhibitors bind to the angiotensin II receptors and decreases the effect of angiotensin II. Therefore vasoconstriction is reduced and blood pressure is reduced.

Angiotensin II inhibitors are used to treat hypertension.

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