Candesartan Dosage
This dosage information may not include all the information needed to use Candesartan safely and effectively. See additional information for Candesartan.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Hypertension
Initial dose: 16 mg orally once a day.
Maintenance dose: Daily ranges of 8 to 32 mg administered once or twice daily.
Usual Adult Dose for Congestive Heart Failure
Initial dose: 4 mg orally once daily. The target dose is 32 mg once daily, achieved by doubling the dose at approximately two-week intervals, as tolerated by the patient.
Renal Dose Adjustments
CrCL < 30 mL/min:
Initial Dose (Hypertension): 8 mg orally once a day.
Liver Dose Adjustments
Consideration should be given to initiation of candesartan at a lower dose in patients with moderate to severe hepatic impairment.
Dose Adjustments
In patients with possible intravascular volume depletion, candesartan should be administered with caution and a lower dose should be considered.
Precautions
Caution is advised when treating older individuals as increased sensitivity to candesartan therapy should be considered.
Dialysis
Candesartan is not removed by hemodialysis. An increased risk of hypotension exists if the dose is given immediately following dialysis. Ideally, the drug should be given when the patient is hemodynamically stable.
Other Comments
If blood pressure is not controlled by candesartan alone, a diuretic may be added.
Compared with Caucasian patients, Black patients have a reduced blood pressure response to monotherapy with angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers; however, the reduced response is largely eliminated if combination therapy that includes an adequate dose of a diuretic is instituted.
