Generic Name: oxymorphone (ox ee MOR fone)
Brand Name: Opana, Opana ER
What is Opana?
Opana (oxymorphone) is an opioid pain medication. An opioid is sometimes called a narcotic.
Opana is used to treat moderate to severe pain. The extended-release form of this medication is for around-the-clock treatment of pain.
Opana may also be used for purposes not listed in this medication guide.
Important information about Opana
You should not take Opana if you have severe breathing problems, if you are having an asthma attack, if you have severe liver disease, or if you have a bowel obstruction called paralytic ileus.
Before using Opana
You should not take Opana if you are allergic to oxymorphone, or if you have:
severe breathing problems or you are having an asthma attack;
severe liver disease; or
if you have a bowel obstruction called paralytic ileus.
To make sure Opana is safe for you, tell your doctor if you have:
a blockage in your digestive tract (stomach or intestines);
asthma, COPD, sleep apnea, or other breathing disorders.
liver or kidney disease;
a history of head injury or brain tumor;
epilepsy or other seizure disorder;
low blood pressure;
a pancreas disorder;
enlarged prostate, urination problems;
mental illness; or
a history of drug or alcohol addiction.
Opana may be habit forming. Never share Opana with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
FDA pregnancy category C. It is not known whether Opana will harm an unborn baby. Oxymorphone may cause addiction or withdrawal symptoms in your newborn if you take the medication during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
See also: Opana pregnancy and breastfeeding warnings (in more detail)
It is not known whether oxymorphone passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Older adults and those who are ill or debilitated may be more likely to have serious side effects.
How should I use Opana?
Take Opana exactly as prescribed. Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Always check your bottle to make sure you have received the correct pills (same brand and type) of medicine prescribed by your doctor. Ask the pharmacist if you have any questions about the medicine you receive at the pharmacy.
Take Opana on an empty stomach, at least 1 hour before or 2 hours after a meal.
Do not crush, chew, or break an extended-release tablet. Swallow it whole.
Some forms of Opana are made with ingredients that are not absorbed in the body. Part of the tablet may appear in your stool. This is a normal side effect and will not make the medication less effective.
Do not stop using Opana suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using Opana.
Store at room temperature away from moisture, heat, and light.
Keep track of the amount of medicine used from each new bottle. Opana is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
After you have stopped using this medication, flush any unused pills down the toilet.
What happens if I miss a dose?
Since Opana is sometimes taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Extended-release Opana is not for use on an as-needed basis for pain.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Opana can be fatal, especially to a child who accidentally swallows it.
Overdose symptoms may include extreme drowsiness, muscle weakness, confusion, cold and clammy skin, pinpoint pupils, shallow breathing, slow heart rate, fainting, or coma.
What should I avoid while using Opana?
Do not drink alcohol while you are taking this medication. Dangerous side effects or death can occur when alcohol is combined with Opana. Check your food and medicine labels to be sure these products do not contain alcohol.
This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how Opana will affect you.
Opana side effects
Get emergency medical help if you have any of these signs of an allergic reaction to Opana: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
a light-headed feeling, like you might pass out;
fever, chills, cough with yellow or green mucus;
stabbing chest pain, wheezing, feeling short of breath; or
Common Opana side effects may include:
dry mouth, nausea, loss of appetite;
stomach pain, constipation, diarrhea;
dizziness, drowsiness, headache, tired feeling;
sleep problems (insomnia); or
mild rash or itching.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Opana side effects (in more detail)
What other drugs will affect Opana?
Taking Opana with other drugs that make you sleepy or slow your breathing can increase these effects. Ask your doctor before taking Opana with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.
Tell your doctor about all other medicines you use, especially:
other narcotic pain medications--buprenorphine, butorphanol, nalbuphine, pentazocine;
bladder or urinary medicines such as darifenacin, fesoterodine, oxybutynin, tolterodine, solifenacin;
bronchodilators such as ipratropium or tiotropium;
cold or allergy medicine that contains an antihistamine;
medication for Parkinson's disease; or
medication to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel syndrome.
This list is not complete and other drugs may interact with oxymorphone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
More Opana resources
- Opana Prescribing Information (FDA)
- Opana MedFacts Consumer Leaflet (Wolters Kluwer)
- Opana Monograph (AHFS DI)
- Opana Advanced Consumer (Micromedex) - Includes Dosage Information
- Oxymorphone Prescribing Information (FDA)
- Opana ER extended-release tablets MedFacts Consumer Leaflet (Wolters Kluwer)
- Opana ER Prescribing Information (FDA)
Where can I get more information?
- Your pharmacist can provide more information about Opana.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Opana only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2013 Cerner Multum, Inc. Version: 7.01. Revision Date: 2013-04-01, 3:19:36 PM.