Generic Name: oxycodone (ox i KOE done)
Brand Name: Oxecta, OxyCONTIN, Oxyfast, Roxicodone, ...show all 11 brand namesOxyIR, M-Oxy, Percolone, ETH-Oxydose, Endocodone, Roxicodone Intensol, Dazidox
What is oxycodone?
Oxycodone is an opioid pain medication. An opioid is sometimes called a narcotic.
Oxycodone is used to treat moderate to severe pain.
The extended-release form of this medicine is for around-the-clock treatment of pain. This form of oxycodone is not for use on an as-needed basis for pain.
Oxycodone may also be used for purposes not listed in this medication guide.
What is the most important information I should know about oxycodone?
You should not use oxycodone if you have severe asthma or breathing problems, or a blockage in your stomach or intestines.
Oxycodone can slow or stop your breathing. Never use this medicine in larger amounts, or for longer than prescribed. Do not crush, break, or open an extended-release pill. Swallow it whole to avoid exposure to a potentially fatal dose. Oxycodone may also be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medicine in a place where others cannot get to it.
MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.
Tell your doctor if you are pregnant. Oxycodone may cause life-threatening addiction and withdrawal symptoms in a newborn.
Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with oxycodone.
What should I discuss with my healthcare provider before using oxycodone?
You should not use oxycodone if you are allergic to it, or if you have:
severe asthma or breathing problems;
a blockage in your stomach or intestines; or
an allergy to any narcotic pain medicine (such as methadone, morphine, Oxycontin, Darvocet, Percocet, Vicodin, Lortab, and many others), or narcotic cough medicine that contains codeine, hydrocodone, or dihydrocodeine.
To make sure oxycodone is safe for you, tell your doctor if you have:
any type of breathing problem or lung disease;
a history of head injury, brain tumor, or seizures;
a history of drug abuse, alcohol addiction, or mental illness;
liver or kidney disease;
Addison's disease or other adrenal gland disorder; or
problems with your gallbladder, pancreas, or thyroid.
Oxycodone is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.
Oxycodone may cause breathing problems, behavior changes, or life-threatening addiction and withdrawal symptoms in your newborn if you take the medicine during pregnancy. Tell your doctor if you are pregnant.
Oxycodone can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using oxycodone.
How should I use oxycodone?
Follow all directions on your prescription label. Oxycodone can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never take oxycodone in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Oxycodone may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. Selling or giving away oxycodone is against the law.
Stop taking all other around-the-clock narcotic pain medicines when you start taking extended-release oxycodone (Oxycontin).
Do not crush, break, or open an extended-release pill. Swallow it whole to avoid exposure to a potentially fatal dose.
If your doctor has told you to take two or more oxycodone tablets per dose, take the tablets one at a time. Do not wet, presoak, or lick the tablet before placing it in your mouth. Drink plenty of water to make swallowing easier and to prevent choking.
Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
Do not stop using oxycodone suddenly after long-term use. Ask your doctor how to avoid withdrawal symptoms when you stop using oxycodone.
Never crush or break an oxycodone pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death with the misuse of oxycodone and similar prescription drugs.
Store at room temperature, away from heat, moisture, and light.
Keep track of the amount of medicine used from each new bottle. Oxycodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Always check your bottle to make sure you have received the correct pills (same brand and type) of medicine prescribed by your doctor. Ask the pharmacist if you have any questions about the medicine you receive at the pharmacy.
Do not keep leftover oxycodone pills or liquid. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush any unused pills or liquid medicine down the toilet.
What happens if I miss a dose?
Since oxycodone is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A oxycodone overdose can be fatal, especially in a child or other person using the medicine without a prescription.
What should I avoid while using oxycodone?
Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with oxycodone. Check your food and medicine labels to be sure these products do not contain alcohol.
This medicine may impair your thinking or reactions. Avoid driving or operating machinery until you know how oxycodone will affect you. Dizziness or severe drowsiness can cause falls or other accidents.
Grapefruit and grapefruit juice may interact with oxycodone and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor.
Oxycodone side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using oxycodone and call your doctor at once if you have:
shallow breathing, slow heartbeat, cold, clammy skin;
confusion, severe drowsiness; or
a light-headed feeling, like you might pass out.
Common side effects may include:
mild drowsiness, headache, dizziness, tired feeling;
stomach pain, nausea, vomiting, constipation, loss of appetite;
dry mouth; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Oxycodone dosing information
Usual Adult Dose for Pain:
The following dosing recommendations can only be considered suggested approaches to what is actually a series of clinical decisions over time in the management of the pain of each individual patient.
-Immediate Release (IR): 5 to 15 mg orally every 4 to 6 hours
-Controlled Release (CR): 10 mg orally every 12 hours
-Solution 5 mg per 5 mL: 5 to 15 mg every 4 to 6 hours
-Solution Concentrate 100 mg/5 mL (20 mg/mL): For patients that have already been titrated to a stable analgesic regimen using lower strengths of oxycodone and who can benefit from use of a smaller volume of oral solution.
-Titrate dose based upon the individual patient response to their initial dose.
-Adjust dose to an acceptable level of analgesia taking into account the improvement in pain intensity and the tolerability.
-Administration of supplemental analgesia for breakthrough pain and titration of the total daily dose may be necessary, especially in patients with rapidly changing disease states.
-When converting from other narcotic pain relievers to oxycodone, the manufacturer product information and/or local protocol should be consulted.
-Doses should be swallowed whole with enough water to ensure complete swallowing immediately after placing in the mouth. Doses should not be crushed or administered via nasogastric, gastric or other feeding tubes as it may cause obstruction.
What other drugs will affect oxycodone?
Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking oxycodone with a sleeping pill, muscle relaxer, other pain medicine, or medicine for anxiety, depression, or seizures.
Other drugs may interact with oxycodone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
More about oxycodone
- Oxycodone capsules
- Oxycodone concentrate
- Oxycodone solution
- Oxycodone sustained-release tablets
- Oxycodone (Advanced Reading)
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about oxycodone.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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