User Reviews for Duloxetine

Also known as: Cymbalta

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Duloxetine.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Dysthymia 1 reviews 3 medications
   
10
Generalized Anxiety Disorder 30 reviews 6 medications
   
7.9
Pain 62 reviews 913 medications
   
7.4
Anxiety 113 reviews 60 medications
   
7.2
Major Depressive Disorder 9 reviews 44 medications
   
7.2
Bipolar Disorder 25 reviews 48 medications
   
7.0
Depression 292 reviews 75 medications
   
6.9
Fibromyalgia 135 reviews 72 medications
   
6.9
Peripheral Neuropathy 15 reviews 6 medications
   
6.8
Osteoarthritis 14 reviews 366 medications
   
6.7
Back Pain 13 reviews 169 medications
   
6.6
Diabetic Peripheral Neuropathy 20 reviews 40 medications
   
6.6
Hot Flashes 4 reviews 30 medications
   
6.1
Chronic Pain 31 reviews 102 medications
   
6.1
Chronic Fatigue Syndrome 5 reviews 2 medications
   
5.7
Urinary Incontinence 3 reviews 50 medications
   
5.2
Small Fiber Neuropathy 0 reviews 0 medications Not rated - Be the first
Summary of Duloxetine reviews 772 reviews 7.0

Reviews for Duloxetine

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Review by 1Gratefuluser:

User Rating:  
   
10

Cymbalta (duloxetine) for Fibromyalgia: I have tried other medications to control my fibromyalgia and I had awful side effects to all then my Dr tried me on Cymbalta and this has been amazing! No side effects. I'm on 120mg now and I feel almost like my old self! It is very expensive though.

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November 29, 2014 9:37 PM

Review by Danvic (taken for 6 months to 1 year):

User Rating:  
   
1.0

Cymbalta (duloxetine) for Fibromyalgia: Did not work only gained weight

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November 24, 2014 9:29 PM

Review by chanf:

User Rating:  
   
9.0

For Urinary Incontinence: Took duloxetine for depression, which it helped enough, but it also worked for my nerve pain and occasional urinary incontinence. I didn't know it was doing the latter until I started weaning myself off of it and got the stress incontinence back. Thought it had gone away on its own.

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November 20, 2014 12:14 AM

Review by ShanBee (taken for 1 to 2 years):

User Rating:  
   
9.0

For Major Depressive Disorder: This medication helped me get my life back. The first 2 months were rough with side effects, I stuck with it like my doctor recommended I do and they all went away!

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November 18, 2014 2:41 PM

Review by MRSDJMCW (taken for 5 to 10 years):

User Rating:  
   
10

Cymbalta (duloxetine) for Depression: Have been on a cocktail of Prozac, Wellbutrin, and Cymbalta for several years for both depression, anxiety, and chronic back pain with GREAT success. Just recently I started to notice I was becoming very short tempered, easily aggravated, and irritable. My Psych gave me .5 mg of Ativan, but also decided to wean me off my Cymbalta 60 mg. The Ativan helped me immensely. Unfortunately,within 2 weeks without my Cymbalta my depression returned, I was sleeping all the time, and worst of all I felt like I could eat everything in the kitchen and still be hungry! Gained weight so quickly,and had no ambition whatsoever. I am now on my 3rd week back on Cymbalta and feeling almost back to normal thankfully! When you find what works for you, stick with it!

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November 3, 2014 7:31 PM

Review by realsis (taken for 1 to 6 months):

User Rating:  
   
9.0

Cymbalta (duloxetine) for Depression: I've tried about 15 to 20 different antidepressants in the last 21 years. Nothing has really helped, or it would help for awhile then stop working. Cymbalta is only the second medication that is not only a SSRI but works with the dopamine in your body, that I've tried. First was Pristiq and that affected me so badly I wouldn't shower for a week. I didn't want to do anything. Now with the Cymbalta I'm more energetic and less hungry and feel much better! So far it's working out wonderfully.

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November 3, 2014 5:11 PM

Review by Anonymous:

User Rating:  
   
10

Cymbalta (duloxetine) for Depression: I was on this medication earlier this year and had to stop it because of cost and insurance. I have since been approved for medical assistance and my doctor has once again prescribed cymbalta for my anxiety and depression. I had no side effects like I did with just about every other antidepressant under the sun. This has saved my life.

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October 28, 2014 9:46 PM

Review by djack2112:

User Rating:  
   
10

Cymbalta (duloxetine) for Fibromyalgia: I had classic fibromyalgia symptoms, after researching many things that would fall into this category, and I was at the point where I was about to give up, literally. I had become depressed, after dealing with fibromyalgia for so long, it had broken me. I have a lot of will power, and normally would have laughed at the thought of taking my own life, but after about 2 years of these symptoms, it was winning, and didn't think I could go on for much longer. So, after trying a couple different medications, I was put on Cymbalta. This medication saved my life. It has reduced my pain levels by at least 2-3 points on a ten point scale, and fixed my mood as well. I cannot say enough about how happy I am with this medication.

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October 25, 2014 4:45 AM

Review by steven0610123 (taken for less than 1 month):

User Rating:  
   
10

Cymbalta (duloxetine) for Major Depressive Disorder: After I started taking this I was glued to this web site reading everybody's positive feedback to give me hope. I had been on it a couple years ago and it worked very well but stopped as life improved with little side effects. A couple years went by and life took a turn for the worse. Going from being very comfortable financially to almost homeless and loosing everything I had including my wife I went to get help. I can not explain in words how horrible I felt. I was in such a dark place this time I had my doubts it would work but it has. I am starting to feel better after a week and a half and hope it continues. I have tried many different anti-depressants mentioned here and none of them worked. Cymbalta saved my life!

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October 23, 2014 8:16 PM

Review by ray of sun (taken for 5 to 10 years):

User Rating:  
   
10

Cymbalta (duloxetine) for Generalized Anxiety Disorder: I been on Cymbalta for 9 years this has been a miracle for me. It helps with anxiety, my chronic pain, my fibromyalgia, my bipolar now just find something to help with anger I'd be perfect. The only side effect I have had is nightmares if I forget to take it that's it. I love my medicine.

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October 14, 2014 1:06 AM

Review by JeanT:

User Rating:  
   
7.0

Cymbalta (duloxetine) for Chronic Pain: Cymbalta has helped enough for me to justify taking it for both chronic pain and dysthymia but do not stop it suddenly! I ran into a doctor vs Insurance problem and went cold turkey for a week and thought I would die. Wean very slowly. If you stop this medicine or stop down to a SSRI then eliminate that. It was the most horrible thing I had ever experienced. It has helped me though.

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October 12, 2014 11:28 PM

Review by trooperhg:

User Rating:  
   
10

Cymbalta (duloxetine) for Osteoarthritis: I was prescribed Cymbalta for anxiety but I have noticed that my osteoarthritis is so much better. I can get out of bed in the morning without hobbling around trying to get my joints working.I can also get up from my chair at work without pain.I am amazed at how much better I feel. Oh & it takes care of my anxiety as well.

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October 9, 2014 3:27 PM

Review by Johnnie3 (taken for 1 to 6 months):

User Rating:  
   
9.0

Cymbalta (duloxetine) for Depression: Tried most antidepressants, and I was ready to give up. I was tired of trying antidepressants, getting sick while I waited for the positives, only to find out it didn't really help. I've tried Prozac, Paxil (good but stopped working for me), Zoloft (allergic to it), Effexor, Citalopram (worst of all). I don't know what made me ask my doctor for Cymbalta, but I did. It started working the second day I took it! I have been slowly recovering from depression and getting my life back. I hope the same for the people who read this. Never give up hope!

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October 6, 2014 4:32 PM

Review by tiffyfish:

User Rating:  
   
10

Cymbalta (duloxetine) for Generalized Anxiety Disorder: Best out of many I tried. Helped the best with least side effects. Added Wellbutrin and combination is awesome. I'm a high functioning person. Abilify at night. All good. Been on over ten years, Abilify recently.

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October 6, 2014 2:03 PM

Review by wfelici (taken for 2 to 5 years):

User Rating:  
   
10

Cymbalta (duloxetine) for Depression: EXCELLENT results. Effexor became non-effective after many years of use and another life impacting event. Was recently severely depressed and suicidal for about 2 years. Found Cymbalta 2 years ago and it CHANGED MY LIFE FOR THE BETTER. I think this medication is FANTASTIC. I have been diagnosed with major depressive disorder and general anxiety disorder (dual diagnosed) This condition has been with me for many years (runs in the family i.e. mother was severely depressed). Cymbalta 120mg per day snapped me out of it. Under doctor's orders I discontinued current SSRI at the time and started right up with Cymbalta 120mg/day. Within 7-10 days I was out of my depressed state. It has to be the norepinephrine aspect that made the difference.

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September 29, 2014 2:02 PM

Review by Stefconradical (taken for 1 to 6 months):

User Rating:  
   
6.0

Cymbalta (duloxetine) for Major Depressive Disorder: Worked well in terms of mood but had terrible side effects.

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September 23, 2014 3:10 PM

Review by Ef1988:

User Rating:  
   
8.0

Cymbalta (duloxetine) for Anxiety: I started taking Cymbalta earlier this year for my anxiety. I found it really helped, but I didn't want to stay on it for long. I had a few side effects while being on Cymbalta such as night sweats, trouble sleeping and electric pulses through my body. Whilst gradually lowering my doses of Cymbalta these side effects did get a little worse, however they have completely gone now. I started lowering my doses in June, and now by the end of August the night sweats have completely stopped, my sleeping is back to normal, and the electric pulses are very rare. When I think about getting worried or anxious now, I just remember that its not a big deal and that if I was on Cymbalta I wouldn't have even thought about it.

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August 27, 2014 1:55 AM

Review by Mystee719 (taken for less than 1 month):

User Rating:  
   
7.0

Cymbalta (duloxetine) for Back Pain: After having tried a few other combination depression, pain medicines, this one finally seemed to work, and I got far less tired, or other side affects I'd gotten from the others, so far, I feel this is the best one I've tried, it has also helped with my mood.

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August 25, 2014 9:42 AM

Review by SusanF. (taken for 2 to 5 years):

User Rating:  
   
9.0

Cymbalta (duloxetine) for Major Depressive Disorder: I use Cymbalta 60mg at night. I sleep better, eat better, and feel better. Doctor diagnosed me with major depression disorder and placed me on Cymbalta and counseling. My life is 90% better! I am so thankful! Oh, and I had my thyroid checked: low thyroid. I take Synthroid 50mcg in the morning.

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August 22, 2014 12:01 AM

Review by BethAnnie:

Cymbalta (duloxetine) for Fibromyalgia: I was diagnosed with Fibromyalgia in 2004. I started out taking Flexeril and Tramadol 37.5. It was helping but I still had bad days. My doctor told me I would have good & bad days. I also tried Lyrica and another medicine (can't remember name that started with a S). Came off of Lyrica and then the S. I was put on Cymbalta started with 60 mg a day then upped to 120mg. It does not help with the Fibromyalgia but it does wonders for my mood swings and hot flashes.

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August 17, 2014 9:51 PM

Review by Meg78:

User Rating:  
   
8.0

Cymbalta (duloxetine) for Anxiety: I'm 5 weeks into taking Duloxetine for depression and anxiety and have had an overall positive experience. My anxiety was greatly reduced after only 4 days on 40mg per day including stopping negative thoughts, no more panic attacks at night etc. The second week I was very tired and depressed without the anxiety, sleeping many hours each day. But by the third week both depression and anxiety were greatly reduced. However by the end of the month the anxiety had started to return slightly and my doctor has now increased the dose to 80mg per day. I had slight nausea, dry mouth and loss of appetite, and some indigestion during the first week or so and now again since I have upped the dose but I imagine these will disappear again soon.

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August 13, 2014 2:48 PM

Review by Stuck on cymbalta (taken for 2 to 5 years):

User Rating:  
   
9.0

For Pain: I'd been taking Cymbalta for about 2 years when I decided that I didn't want to pay $30/mo anymore, so I decided that I would wean myself off. I tried and I started getting the brain zaps, like lightening in my head. So I started back, slowly I just started missing a dose here and there until I was able to stop them without the side effects. I've been off for several months now and I've noticed that I've been in more pain and everything that was hurting me before has compounded. So needless to say I'm starting them back. Appears that I'm not going to be able to do without it.

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August 12, 2014 10:57 PM

Review by pjs001:

User Rating:  
   
3.0

Cymbalta (duloxetine) for Osteoarthritis: I was prescribed Cymbalta for arthritic pain in my knees. I took 30 mg/day for 3 days and was fatigued to the point of not wanting to do anything but lie down.In addition (to which I found out was a rare side effect) I was yawning all day and evening. After reading about the difficulties that some people had getting off this medicine. I stopped it after the 3 days. Unless I can be somewhat assured that the side effects are temporary I would rather live with the pain then take this medicine.

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August 6, 2014 4:43 PM

Review by king bean (taken for 1 to 6 months):

User Rating:  
   
4.0

Cymbalta (duloxetine) for Anxiety: Didn't work for me. Felt pretty barfy and crummy first several days. Seemed to make me agitated. Only on it for a week; withdrawal was unpleasant. Just my experience, however.

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August 4, 2014 2:33 PM

Review by KRW2011:

User Rating:  
   
8.0

Cymbalta (duloxetine) for Generalized Anxiety Disorder: I have been taking Cymbalta for two years now- it honestly changed my life. At the time I started taking it I was a college athlete and anxiety ruled my life. At first, I would take it during the morning hours and I would immediately want to go to bed. That was my problem, I needed to take it about an hour or two before bed. I am still experimenting the exact right time to take it (I sometimes wake up still feeling tired from it- but not sure if it's the medication or my routine now). I know certain medications work for some and not others, but I would recommend this medication. I had slight symptoms at first beside the tiredness- decreased appetite and no sexual desires or emotions. I still feel great! (30mg once daily)

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July 24, 2014 11:58 AM

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