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User Reviews for Duloxetine

Also known as: Cymbalta, Irenka

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Duloxetine.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Dysthymia 1 reviews 3 medications
   
10
Generalized Anxiety Disorder 42 reviews 7 medications
   
7.9
Pain 62 reviews 906 medications
   
7.4
Anxiety 123 reviews 60 medications
   
7.2
Osteoarthritis 16 reviews 340 medications
   
7.1
Bipolar Disorder 25 reviews 32 medications
   
7.0
Major Depressive Disorder 20 reviews 46 medications
   
7.0
Depression 325 reviews 76 medications
   
6.9
Fibromyalgia 153 reviews 20 medications
   
6.8
Peripheral Neuropathy 15 reviews 6 medications
   
6.8
Back Pain 17 reviews 176 medications
   
6.8
Diabetic Peripheral Neuropathy 22 reviews 41 medications
   
6.7
Chronic Pain 51 reviews 106 medications
   
6.2
Hot Flashes 4 reviews 19 medications
   
6.1
Chronic Fatigue Syndrome 5 reviews 2 medications
   
5.7
Urinary Incontinence 3 reviews 49 medications
   
5.2
Small Fiber Neuropathy 0 reviews 0 medications Not rated - Be the first
Summary of Duloxetine reviews 884 reviews 6.9

Reviews for Duloxetine

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Cymbalta (duloxetine) for Generalized Anxiety Disorder: "I was on celexa for a few yrs.n when I started feeling "well" again decided to stop taking it. Within a yr. I was constantly crying n went back on it but it affected my ability to Fully enjoy intimacy so the mental health nurse told me ask my Dr.for pristine, which I did n he prescribed my cymbalta instead which I took a long with my celexa. When I went back to c him he said that he told me stop the celexa n prescribed me 60mg.of cymbalta a day which I now have been on for about a yr. To say it's a godsend is an understatement. I actually went to an outside concert with approx.5000 people in attendance. Although I was still a little anxious a couple drinks helped me to somewhat enjoy myself. Normally crowds cause me unbearable anxiety."

   
8.0

choose to b happy August 15, 2015

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Cymbalta (duloxetine) for Fibromyalgia: "Cymbalta actually did help, but please talk to your Dr as soon as possible if you notice any changes in your vision. I was literally 2 weeks away from going blind .I was in my early 40s and developed severe cataracts in both eyes very quickly. After seeing several doctors and specialists I had them removed.One of the specialists did research and found that cymbalta was the cause, a very rare side effect but it can happen."

   
8.0

gemkat65 (taken for 5 to 10 years) August 15, 2015

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Cymbalta (duloxetine) for Chronic Pain: "Besides extreme sweating (soaking thru tee shirts) 24/7 I don't see what it does for pain besides NOTHING, the feeling of I don't give a rats ass about my life is another fun filled side effect. I've been on it almost a yr, take 30 mg in the morning before going to bed & 60 late in the day. I'm thinking of weaning myself off it, I'd rather take Xanax twice a day."

   
4.0

nitejaitor August 13, 2015

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Cymbalta (duloxetine) for Chronic Pain: "Was given 30mg cymbalta for pain in hip as well as depression due to chronic pain. It's been 2months, after about 3weeks of many side affects, diarrhea, nausea, headache, the pharmacy told me to stick with it, they will pass. They have except I've gained about 5lbs. The depression is better, the pain isn't any better, in fact seems to be getting worse. I don't think the cymbalta is making the pain worse, I think my hip is just getting worse. But not happy about the weight gain since I was fighting my weight before I took it. And being heavier can't be good for a bad hip."

   
1.0

abnermalchik (taken for 1 to 6 months) August 11, 2015

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Cymbalta (duloxetine) for Chronic Pain: "I have been taking Cymbalta for joint & muscle pain due to hemochromatosis for about 6 weeks now and it has made a huge difference, and I find that I have almost no side effects. For the first week or so the side effects were terrible, but they eased up after that."

   
9.0

HHgirl August 6, 2015

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Cymbalta (duloxetine) for Major Depressive Disorder: "I'm one of the lucky ones with minimal side effects. I couldn't fall asleep for the first week but now I am sleeping very well and see a lot of vivid dreams. My appetite is decreased and I am losing weight which makes me happy because I tended to overeat and I needed to lose some weight. I am exercising every second day. I am taking the drug for major depressive disorder and severe anxiety. My anxiety was gone by approximately the third day of using it. My negative thinking decreased. Before taking Cymbalta I was constantly feeling fear, I was waking up at night, my thinking was severely impaired by negative thinking, I was constantly feeling like crying, I felt dumb in general and wanted to die. I'm back to life now."

   
10

CountingZebra (taken for 1 to 6 months) August 3, 2015

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Cymbalta (duloxetine) for Depression: "I have been on Cymbalta for about 3 months. It helped with depression but made me tired most of the time. A week ago, my doctor increased my dosage from 60mg to 90mg and I developed a UTI and have very intense middle back pain. UTI has been cured but back pain persists. I just read on a few different threads that cymbalta caused others to develop bladder infections and back pain, two things I never had prior to taking this drug. This drug also causes me to sweat profusely to the point I feel like I am about to drown in my own sweat. I was never a sweater. I am going to discontinue this drug."

   
6.0

Anonymous (taken for 1 to 6 months) August 3, 2015

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Cymbalta (duloxetine) for Fibromyalgia: "At first I thought this was a miracle drug but after about 2 months they had to double my dosage then in about another 2 months later the same thing. Next thing you know I'm on the max dosage with no symptom relief. OMG that's when the real nightmare started. It was almost impossible to stop. I was ready to check in a a hospital. My doctor did watch me and did her best to get me off the medication safely but it was really really hard. Even though it did not help my fibromyalgia I suffered from withdrawal. Please PLEASE really read the side effects before taking this medication."

   
5.0

AvaRodgers August 2, 2015

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Cymbalta (duloxetine) for Anxiety: "I took Cymbalta for anxiety and depression. Over the years, I took anywhere from 30-120 mg. I think around 60 mg was most effective with fewest side effects, but I still experienced tons of anxiety while on it. At 120 mg, I had bizarre psychomotor symptoms - for example, in order to fall asleep, I had to rock back and forth. The same day that I decreased from 60 mg to 30 mg, I noticed the return of an OCD-style facial tic I hadn't had since middle school (I'm 25). Side effects included drastically increased sweating, "brain zap" headaches, and difficulty finding the right words (which may be permanent, as I've been off Cymbalta for 3 weeks and continue to experience it)."

   
2.0

lou3 (taken for 2 to 5 years) July 31, 2015

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Cymbalta (duloxetine) for Fibromyalgia: "Cymbalta did not help me at all he was prescribed to me for neuropathy pain and it did nothing for me."

Cymbalta didnt help me at all (taken for 1 to 2 years) July 31, 2015

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Cymbalta (duloxetine) for Generalized Anxiety Disorder: "I initially took Cymbalta for distonia, which was involuntary movement in my hands caused by a type of Muscular Dystrophy. A combination of Cymbalta, Neurontin, and Tramadol are very effective in reducing my pain. After several months I noticed a great change in my personality. To make a long story short, I realize I've dealt with anxiety most of my life. Cymbalta has literally changed my life. If this medication had been available in the 1960's or 1970's my life would have been dramatically different. I can't imagine life without Cymbalta."

   
10

Kev1957 July 30, 2015

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Cymbalta (duloxetine) for Depression: "I've been on Cymbalta for many years after my doctor had tried a number of antidepressant medications. It has worked wonderfully for me and kept me on an even keel since I began taking it. I am lucky that I had a good experience with this medication."

   
10

JoeLawman (taken for 10 years or more) July 24, 2015

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Cymbalta (duloxetine) for Fibromyalgia: "I have Fibromyalgia as well and I stopped taking Cymbalta because my pains improved a great deal, but, I had extreme nausea and exhaustion (esp. in the am). Now my pains have come back to kick my behind. Day 2 of Cymbalta. Seems as if it makes me light sensitive, which gives me a headache and dizzy. Like my eyes are heavy and my skin was clammy. I will continue. I'll get back to you n a few weeks."

   
6.0

Dana Strawberry July 23, 2015

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Cymbalta (duloxetine) for Generalized Anxiety Disorder: "I have a lot of stress, and I find its not working for me. Made me dizzy at first. I honestly don't like cymbalta"

   
2.0

Anonymous (taken for 1 to 6 months) July 23, 2015

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Cymbalta (duloxetine) for Major Depressive Disorder: "Was one 60 mg for 4 years, had some relief from panic attack with depression. Had some rough times job related, medical issues not related to above, and doctor increased to 120 mg. normal dosage is no more than 60mg according to insert in med bottle and Internet. After 3 years on this dose it quit working. The withdrawal was the worst thing ever. During taking Cymbalta, I developed diabetes. Withdrawal took 8 months and pdoc gave me lamorigine, an anti seizure med for withdrawal. As I tapered off my diabetes went away! Pdoc denied Cymbalta caused it. I googled it and proof, all SSRI's can cause hyperglycemia! I've tried everything from Prozac to lexipro. Same crap. Now on transidone and back to having normal feelings"

   
2.0

muszakman (taken for 5 to 10 years) July 22, 2015

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Cymbalta (duloxetine) for Anxiety: "After several years of Zoloft use for GAD, I went off of it, under my dr's supervision. Felt Ok, then last year, had a lot of chronic pain, back & arthritis...heard that Cymbalta was good for all those--pain, depression and anxiety. Psych doc gave me samples, seemed to kick in pretty well & quickly. I have gone through 3 major surgeries in the last 18 months--and went off the Cymbalta b/c I thought I could handle it...Nope, I'm a mess. Needed daily clonazepam to cope. I just went though a 3rd and (Hopefully!!) final surgery 5 weeks ago. Hadn't taken any Cymbalta for months. I am going back on. Just got thru the worst anxiety attacks in my life following the 3rd surgery. I think the dose for me was 60mgs, and I will start it up again."

   
8.0

MidKid (taken for 1 to 2 years) July 20, 2015

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For Chronic Pain: "I've been taking Cymbalta/Duloxetine for two years. I suffer from chronic pain due to what doctors and specialists call " I don't know ." It helps me when used with diclofenac, tizanidine and hydrocodone. It lessens my symptoms so that doctors and people who never suffered from pain, stop nagging me about a possible addiction to hydrocodone because i take less now. The unexpected bonus is that I function much better in everyday life. Without knowing, the constant pain put me in a severe depression and i missed a couple of years of my life. Also without knowing, I went my whole life ( I'm fifty one now) suffering from anxiety even though highly functional. Cymbalta brought me back to the world and my family with only mild side effects ."

   
8.0

Herbert88 (taken for 2 to 5 years) July 19, 2015

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Cymbalta (duloxetine) for Depression: "I was given Cymbalta to help with my pain and depression, it helped both and I felt like a new person until I developed terrible sweats, so bad they consumed my living a normal life. I was referred to an endocrinologist to determine what was causing the sweats. I was tested for everything imaginable with no clue as to what was causing my problem. This went on for about a year. I was at my whits end. I was on the internet looking at my medications and saw that Cymbalta could cause sweats. Right then I decided to stop taking Cymbalta, on my own not consulting my Dr. To my amazement within two weeks or less my sweats stopped. I am writing this because I am hoping I can help someone else who has these terrible side effects."

maydec (taken for 1 to 2 years) July 18, 2015

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Cymbalta (duloxetine) for Major Depressive Disorder: "I have been depressed and have anxiety for years since i was 6. im 55 now. No one new anything back then why I was a nut case out of control thoughts actions major moods swings and instant anger. no remorse no empathy nothing just hate and pure panic. I have tried all kinds of different meds for the last 15 years and some were OK but nothing like these. My god I do 60mg twice a day. no side effects, no anger, no mood swings, no depression or anything, its all gone everything. you have no idea the great feeling it is to think normal act normal be polite and thoughtful, caring understanding, just incredible difference. I was taken off them for 5 weeks to try something else to see if it was me or the meds. back to the old me instantly. lifer.."

   
10

Just_Happy_Now July 17, 2015

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Cymbalta (duloxetine) for Chronic Pain: "First placed on medication for severe arthritis of one hip. Helped with pain at the lower dose however eventually I needed an increased dose. The increased dose increased my nausea, weird dreams, itchy skin and twitching. My blood pressure also increased. I began to stumble and fall while walking slowly. My nerves seemed to cause me to tremble internally. Currently I am tired all the time however I can not stay asleep at night. Last year I tried to get off the medication however I had severe withdrawal. I had trouble standing up, I was so dizzy and my stomach was upset. I will soon be getting a hip replacement since the side effects decrease your quality of life. I am withdrawing from this medication prior to surgery."

   
8.0

MtRose July 16, 2015

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Cymbalta (duloxetine) for Chronic Pain: "I have only been on this med for two days, but OMG what a difference! I have been in pain mgmt for 25 years for interstitial cystitis and during this time I went from being an energetic, happy person to nothing more than a shell. As the pain and pain med amounts increased, the quality of my so called life decreased to the point that for the last year I do ABSOLUTELY NOTHING but sit on the couch and read. No cooking, no cleaning, no going out, nothing! But after only 2 days, I'm starting to feel like my old self again! Much more energy and have even taken less pain Meds! I haven't had any side effects. Can't wait to see how this goes! Sooooo grateful!"

   
9.0

Monismystique July 16, 2015

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For Chronic Pain: "I am 74 years old and have been suffering from spinal stenosis and osteoarthritis for over 12 years. I had 2 lumbar and 2 cervical surgeries with a total of 8 laminectomies and 8 fused joints. The pain clinic had prescribed a regimen of morphine for a couple years which helped a little. After my 4th lumbar surgery I suffered lower back pain for over 2 years. I stopped morphine treatment last year and have started 30 mg duloxetine, twice daily now for less than a week and can't believe the results. Almost immediate relief of most lumbar pain, and I am walking without a cane. The side effects are minimal, and I will gratefully cope with them if this relief continues."

   
8.0

Bill O July 11, 2015

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For Chronic Pain: "I've been on this SNRI for about 3 months and have been pleased. I was on Lexapro and then stepped up for something that would address pain issues as well. I lost all the weight I gained on Lexapro, 40lbs! I'd say I've had maybe a 15-20% reduction in back pain and hip pain. The sex drive has also ramped up and I have more energy. Hey, I'll take it. I have heard about issues with coming off the medication. However this is true of many psychiatric medications and pain medications, this med is both so it only makes sense that stopping suddenly isn't advisable. If you can't afford your prescription you can get a few days emergency supply from your pharmacy. Also check the manufacturer website for coupons."

   
9.0

Brokedown Palace (taken for 1 to 6 months) July 9, 2015

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For Depression: "I have suffered anxiety and depression on/off all my adult life. In 2013 I was prescribed Duloxetine, I suffered 20 days of hell due to the side effects. Suicidal thoughts, mood swings, and limb twitching. Side effects improved once I came off duloxetine but still suffered muscular twitches several months later. "

   
1.0

mkt66 July 5, 2015

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Cymbalta (duloxetine) for Depression: "I have been on Cymbalta for 6 years. I am 51 and have a family history of depression and only recently have I accepted that I may have it very long term. For those in Australia I recommend the generic version called Coperin (I get it from Priceline) which reduces the 'brain fog' of Cymbalta. I have been very happy on Cymbalta (Coperin), it changed my life. I hate that I rely on a tablet to enjoy life, but it is a small price to pay. My GP occasionally suggests I try a new drug but I always refuse. I have much improved relationships with people and it is great to have lost the anxiety which has completely disappeared. I have been on 30mg for 4 years, but am increasing to 60mg for a few weeks as I seem to be going through a bout of anxiety."

   
9.0

familyhistory (taken for 5 to 10 years) June 28, 2015

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