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User Reviews for Duloxetine

Also known as: Cymbalta

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Duloxetine Ratings Summary

User Ratings

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20%
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12%
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Key Statistics

7.5/10 Average Rating

45 Ratings   39 User Reviews

Compare all 1584 medications used in the treatment of Pain

Reviews for Duloxetine to treat Pain

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Review by jomanda:

Cymbalta (duloxetine): Cymbalta provided amazing relief for my neuropathic pain and depression though it also seemed to have bad side effects. The night terrors I experienced were unimaginable and occurred almost nightly. I had taken this medication for over a year and after choosing to discontinue it, the withdrawal symptoms that followed seemed severe. I would advise a cautious approach.

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September 27, 2007 6:41 AM
Review by nanalou:

Cymbalta (duloxetine): I used Cymbalta for a year. The first 8 months were great in alleviating my all-over pain, which is why I was taking it. After that, slowly it came back until I asked to be taken off. In the first few days I had pounding of my heart which was so bad I never slept all night. MD put me on another blood pressure pill which helped after upping the dosage a couple times. After weaning off, heart pounding & insomnia started again.

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August 20, 2007 9:07 AM
Review by Anonymous:
User Rating:  
  
10

Cymbalta (duloxetine): This drug is fantastic. I had neuropathic pain and depression, due to the chronic pain, for over six months. I tried NSAIDS and other drugs which did little, if anything. Cymbalta really saved me. I tolerated it well and had few side effects, dry mouth and a little wired for the first week on it but that was it. It did reduce sexual performance and cause difficulty with orgasm, but it was worth it. After 10 months I got off of it and everything returned but the pain. Fantastic.

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April 2, 2008 6:14 AM
Review by Anonymous:
User Rating:  
  
8.0

Cymbalta (duloxetine): I've been on Cymbalta for fibro pain for about two months. For me, it's working well. I have no side-effects, and it's made me feel like I've only been hit by a compact car instead of a mack truck! lol!

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April 6, 2008 3:58 AM
Review by Charles666:
User Rating:  
  
10

Cymbalta (duloxetine): I've had Occipital Neuralgia for nearly 3 years and have gone through 8 Neurologists who tried all the current treatments including radio frequency ablation (burning) without long term relief. We decided to try some of the anti-depressant medications and started with Cymbalta. In 3 months I was pain free and have had no problems since I started the drug about 2 years ago.

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March 2, 2008 10:54 AM
Review by Anonymous:
User Rating:  
  
9.0

Cymbalta (duloxetine): I've been on Cymbalta for a year now. I had a bad truck wreck and had to have my neck fused. I was taking 60mg of hydrocodone and it kept me from taking care of my company. Started with 60mg of Cymbalta and after about six months went to 30mg. Things so far have been great. My wife is happy because my bad temper has gone. Side affects have been, sweating bad at night and less sleep. Over all it has been a life saver.

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May 4, 2008 10:42 PM
Review by BiPolarNeuro:

Cymbalta (duloxetine): I was originally prescribed Cymbalta for relief of pain caused by neuropathy in my leg. I have bipolar disorder. At the time I was unaware it was an anti-depressant. Bipolar patients should monitor themselves for symptoms of mania while taking Cymbalta. I was thrown into a wild episode of mania within 3 weeks of taking a 60 mg dose of Cymbalta.

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October 12, 2007 4:28 PM
Review by Anonymous:
User Rating:  
  
1.0

Cymbalta (duloxetine): My MD prescribed Cymbalta for chronic pain caused by disc bulges, in addition to treating my previously diagnosed depression and anxiety. I took my first dose around noon, and by 2pm had a pounding headache. As the day continued, I began to have tremors and convulsions, blurred vision and was very disoriented. At 10 pm my heart rate and breathing were very rapid and I had mild hallucinations. I rode it out for the rest of the night and after about 3 hours most of the side effects had faded with the exception of the headache. Unfortunately, the worst side effects was yet to come, graphic vivid nightmares. My doctor took me off the medication, after one dose, three days ago.

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January 16, 2010 12:45 AM
Review by Anonymous:

Cymbalta (duloxetine): I have been taking Cymbalta for leg pain for about a year. It was very effective in relieving my leg pain related to back problems/Anklylosing Spondylitis. However, it has been necessary to increase my dosage twice. I am now on the highest dosage and pray that it will keep working as a miracle cure for my leg pain. By the way, I have had no side effects except dry mouth.

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March 2, 2008 11:20 PM
Review by Anonymous:
User Rating:  
  
8.0

Cymbalta (duloxetine): I have neuropathy in my feet and slightly in my hands. Amitryptiline made my pain livable - still bad, but I could function. When I began taking Cymbalta along with the amitryptline, almost immediately the pain subsided and practically disappeared! I no long take the Amitryptiline and Cymbalta keeps the pain to a low ebb, allowing me to sleep and join in activities I had long given up. Doesn't do a thing for my "attitude", but being relatively pain free does make me happy.

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March 26, 2008 4:27 PM
Review by Anonymous:
User Rating:  
  
10

Cymbalta (duloxetine): I have been taking Cymbalta for about 2 years. I was prescribed it as a test for migraines. I have not had a migraine in the last 2 years. Thank so much for giving me my life back.

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October 8, 2008 10:18 PM
Review by Anonymous:

Cymbalta (duloxetine): I find that this helps with my pain. I also take etodolac, staflex and lyrica. I have ankylosing spondylitis and osteoarthritis and fibromyalgia that staflex controls. I also have restless leg syndrome. Just thought I'd weigh in and let you know that I know this drug has helped my pain.

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August 2, 2008 11:27 AM
Review by Anonymous:
User Rating:  
  
6.0

Cymbalta (duloxetine): I have had chronic pain from nerve damage when I had a mastectomy 11 yrs ago. Have been to many pain doctors, tried epilepsy medicines, antidepressants, and now I am taking Tizanidine, Lyrica, Cymbalta and a wonderful compounded pain cream that is a lifesaver for me! It has Lidocaine, Ketoprofen, and Cyclobenzaprine. Mention to your pain doctor. I put a small dab on my arthritic knee too. My insurance covers it 90%. Good luck to all with chronic pain!

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September 14, 2009 11:59 PM
Review by Anonymous:
User Rating:  
  
8.0

Cymbalta (duloxetine): I have been on Cymbalta for 2 months and it has really help my back pain. I have had chronic back pain for 3 years due to a fall. I have had my back MRI and I have no disks problems, so it is muscle pain. Cymbalta has really helped. It does still bother me some days but not as much as before. In the beginning I had a lot of nausea with Cymbalta but that went away after about a week, I was determined to give it a chance. With some of the side effects it is easy to give up, but it does get better. Now I have no problems, maybe a little less of an appetite, but that might not be such a bad thing.

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January 11, 2011 11:32 AM
Review by Anonymous:

Cymbalta (duloxetine): I was placed on this medication a year ago after years of suffering with pain due to a car accident. I nearly lost my life in 1993 in car accident. The pain at times became unbearable, so my Doctor suggested this medication and I have seen much success with it.

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June 10, 2009 2:48 PM
Review by Anonymous:
User Rating:  
  
7.0

Cymbalta (duloxetine): For me, this worked great as pain relief for a herniated disc. I found the pain to be less agonizing throughout the day, and I could do things that I needed to (cleaning, vacuuming, grocery shopping, carrying the groceries, etc.). The problem that I had with the medication is that I had horrible memory loss. I am a full-time student and could not handle the problems I had trying to retain hard information. My doctor tried to combat this by putting me on Ritalin but then I couldn't sleep. I have had to go off of pain relievers for this exact problem.

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August 19, 2009 2:20 AM
Review by ccdny:
User Rating:  
  
9.0

Cymbalta (duloxetine): I use Cymbalta for Fibromyalgia. I am in the land of living once again.

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November 20, 2010 11:34 PM
Review by SunnyEllie:
User Rating:  
  
8.0

Cymbalta (duloxetine): I don't think this drug does a whole lot for my pain but I think it keeps me from becoming depressed. It seems to work very well for stabilizing my mood.

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August 27, 2009 3:40 PM
Review by Nikki W:
User Rating:  
  
10

Cymbalta (duloxetine): I have had severe lower back pain for many years. I have 2 bulging disc, 1 ruptured disc which causes paralysis and severe pain in my left leg, degenerative disc, arthritis and a small deformity on my lower spine and I'm only 40 years old. I'm on the couch and unable to walk a lot of the time. The pain was so severe. The doctor put me on Cymbalta and referred me to a neurosurgeon. The neurosurgeon finally said they would do surgery to fuse my lower back. I have been on Cymbalta for a little over 3 months now and I'm pain free. I have canceled my surgery. I have my life back. Love it.

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August 3, 2011 2:58 PM
Review by Anonymous:
User Rating:  
  
9.0

Cymbalta (duloxetine): This drug has been a life saver for me. I had severe upper stomach pain before taking Cymbalta. The pain was gone within two weeks.

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September 11, 2009 8:19 PM
Review by brian25503:
User Rating:  
  
8.0

Cymbalta (duloxetine): I have been using cymbalta for about 6 months now, I have severe leg pain caused by compartment syndrome and chronic low back pain and my md has me on cymbalta and lyrica for this pain and it has kept it under control, I still have to take percocet a few times a day but my pain is better with cymbalta and my depression has even gotten a lot better. Two birds with one stone type of deal.

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June 12, 2010 6:31 PM
Review by Becky Rae:
User Rating:  
  
8.0

Cymbalta (duloxetine): I started taking Cymbalta in April 2011, and when I first started out on it I experienced, extreme tiredness, insomnia, dry mouth, constipation, hot flashes, strange dreams. I still get very odd sometimes disturbing dreams but I think a lot of it has to do with recent stresses in my life (grandma having a stroke, work stress) and still experience constipation, hot flashes, and night sweats but it's not the end of the world. It has so far been the only antidepressant medication that has really helped me and I have been on lots of different SSRI's and atypical antipsychotics. I have good and bad days like anyone does, but if I do get sad and cry it doesn't seem to last long. So in my opinion the benefits outweigh the side effects.

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July 3, 2011 11:25 PM
Review by Anonymous:
User Rating:  
  
9.0

Cymbalta (duloxetine): I have chronic pain from a broken arm and two surgeries last year. I've tried EVERYTHING - this is the only non-narcotic medicine that has worked for me. The only negative is that it doesn't have a generic equivalent and my insurance doesn't cover it. That's a pretty big negative.

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May 1, 2011 5:57 PM
Review by Anonymous:
User Rating:  
  
9.0

Cymbalta (duloxetine): I have had severe back pain for over 10 years after two car accidents. I was also unable to turn my head without neck pain. After taking Cymbalta I have little to no pain. I pray it continues to work. It's amazing.

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June 14, 2011 7:38 AM
Review by jimmy161:
User Rating:  
  
9.0

Cymbalta (duloxetine): I am pain free at night for the first time in years. I do have some side effects but they are not nearly as bad as the side effects I was having with pain medication.

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July 11, 2011 4:06 PM

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