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Duloxetine for Pain User Reviews (Page 2)

Brand names: Cymbalta, Drizalma Sprinkle, Irenka

Duloxetine has an average rating of 7.1 out of 10 from a total of 78 reviews for the off-label treatment of Pain. 68% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Duloxetine

  • Anonymous
  • August 2, 2008

Cymbalta (duloxetine) "I find that this helps with my pain. I also take etodolac, staflex and lyrica. I have ankylosing spondylitis and osteoarthritis and fibromyalgia that staflex controls. I also have restless leg syndrome. Just thought I'd weigh in and let you know that I know this drug has helped my pain."

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  • Nana...
  • Taken for less than 1 month
  • September 20, 2012

Cymbalta (duloxetine) "I've had Frozen Shoulder for 8 months. If you aren't familiar with frozen shoulder, it is not only inconvenient because of the inability to move your arm, it is terribly painful. It takes usually about 12 to 24 months to get over it, and I've been on Vicodin, Tramodol, Advil and other pain killers for this, while doing physical therapy. I also have a topical prescription compound for my pain. I was at my wit's end when my doctor came up with the idea of Cymbalta. It seems to have been a great idea. I have a little dry mouth, but I am about 80 percent pain free. I still can't 'Move' my arm, but with physical therapy, that will come in time. It used to hurt (REALLY HURT) 24/7!"

8 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • July 16, 2012

Cymbalta (duloxetine) "After the removal of a tumour and bone graft surgery I suffered from debilitating pain that occurred at night which ultimately kept me from sleeping. For years, me and the doctors searched for the source of the pain but they could not find a reason and I was told to live with it. This year I was suggested Cymbalta because my doctor had said it was working as a pain reliever for other patients. I was willing to try anything to rid the pain and After about 3 weeks I noticed a dramatic decrease in my pain. After a few months I am practically pain free. For those who deal with chronic pain on a daily basis this is best thing that could happen. I never thought anything would help, Cymbalta has given me my life back."

10 / 10
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Frequently asked questions

  • Anonymous
  • June 10, 2009

Cymbalta (duloxetine) "I was placed on this medication a year ago after years of suffering with pain due to a car accident. I nearly lost my life in 1993 in car accident. The pain at times became unbearable, so my Doctor suggested this medication and I have seen much success with it."

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  • JAM
  • August 30, 2017

"I had Shingles in March and was given two meds - one was an antiviral and the other for pain. The pain pill they gave me didn't mix with my meds. I went without the pain med. Then the beginning of April the pain came. It got worse and worse. April, May, June, July ever increasing pain around the shingles area. Went to my family doctor in Jul and she prescribed Doloxtine 30mg. Well I read the pill first. I read and wanted to avoid ALL Side affects. So I continued without the pill and took tramadol and a local ointment. The pain was constant and intense. Aug 3 back to my family Doc. She insisted I try the Doloxtine about 3 days later almost no pain. Yesterday she increased it to 60mg. So far so good, I shouldn't be so stubborn."

8 / 10
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Are you taking this medicine?

  • Anonymous
  • August 19, 2009

Cymbalta (duloxetine) "For me, this worked great as pain relief for a herniated disc. I found the pain to be less agonizing throughout the day, and I could do things that I needed to (cleaning, vacuuming, grocery shopping, carrying the groceries, etc.). The problem that I had with the medication is that I had horrible memory loss. I am a full-time student and could not handle the problems I had trying to retain hard information. My doctor tried to combat this by putting me on Ritalin but then I couldn't sleep. I have had to go off of pain relievers for this exact problem."

7 / 10
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  • Nancy
  • Taken for less than 1 month
  • June 10, 2021

"I've spent more than an hour typing and revising my story about how Cymbalta has changed my life, but every time I submit my remarks, I'm told my comment is too long. So. Cymbalta helped me with my 34 years of Meralgia Paresthetica!! There!"

9 / 10
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More FAQ

  • Chas
  • Taken for 2 to 5 years
  • August 3, 2012

Cymbalta (duloxetine) "I had developed occipital neuralgia as a result of Tourette's syndrome. The pain in my neck was very severe so I went to a pain management clinic where I was treated with methadone, Lyrica (caused serious side reactions), injections of steroids and some other medications, and finally by radiofrequency ablation. All this took three years and I was out of options. I read that Cymbalta was good for neuropathic pain so I got a prescription and started taking it. After about 6-7 weeks, I was pain free. I found it hard to believe. I later switched to Wellbutrin and remained pain free."

10 / 10
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  • Anonymous
  • September 9, 2011

Cymbalta (duloxetine) "I just took a first dose of 30 mg of Cymbalta at 4:45 p.m. and by 9:30 p.m. I developed nausea. The nausea subsided by 11:00 and the pain in my feet seemed to melt away. I have suffered for many years with chronic pain from degenerative bone spurs in my spine and fibromyalgia in my feet. This gives me a warm comfortable feeling. I pray this will work for a long time. Being in so much pain for so long and having this relief sure takes the edge off. Thanks for the relief."

7 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • July 1, 2012

Cymbalta (duloxetine) "After 3 years of crippling lower back pain and radiculopathy from L-5 spondylolysthesis, I tried 60 mg of cymbalta : complete game-changer. I experience slight nausea a few times a week, but that's all. I'm back to being a happy, nearly pain -free dad. If I hadn't tried this, I would be facing surgery by now. What a blessing."

9 / 10
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  • Anonymous
  • June 14, 2011

Cymbalta (duloxetine) "I have had severe back pain for over 10 years after two car accidents. I was also unable to turn my head without neck pain. After taking Cymbalta I have little to no pain. I pray it continues to work. It's amazing."

9 / 10
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  • Anonymous
  • December 14, 2011

Cymbalta (duloxetine) "I have fibromyalgia, rheumatoid arthritis, osteoarthritis, have had a hip replacement and extensive back surgery for spinal stenosis. I had pain constantly at times almost to the point I could hardly walk. After beginning Cymbalta the pain left. I feel like I did 25 or 30 years ago. I have had no negative side effects except an occasional mild headache and night sweats some nights. This medication has been a life-saver, even stopping the nerve pains shooting down my legs. It's worth trying it!"

10 / 10
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  • LE050...
  • Taken for 1 to 6 months
  • May 2, 2012

Cymbalta (duloxetine) "This medicine is amazing! I have suffered from a bulging disc and facet joint issues for a year with little lasting relief from injections. I was prescribed Cymbalta a little over a month ago and by the 3rd or 4th day on it I was almost literally pain free. I was afraid to say it out loud for fear that I would jinx myself because it was almost too good to be true. Now after being on it for 5 weeks I can workout and get back into my exercise regimen with little to no pain. This has truly been a lifesaver! I did have tiredness and low motivation during the first two weeks, but my body seems very acclimated to it now. I do sweat a lot at night, but I can live with it. Love this medication."

9 / 10
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  • Anonymous
  • April 24, 2012

Cymbalta (duloxetine) "I've had lower back pain for over a year and several doctors later, I was put on Cymbalta. I could not handle the side effects. I was having horrible dreams, sweats, felt nauseated, shakes, and felt really out of it with dizziness and confusion. This was a 30 mg dose, I'm not on any other medicines."

1 / 10
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  • Anonymous
  • March 27, 2012

Cymbalta (duloxetine) "Been on 30mg Cymbalta for 2 weeks. Started getting relief by the 2nd day. Am 58 year old male with spinal stenosis, degenerative disc disease, and spondy. Plan was to go to 60mg but I am getting enough relief at 30mg. I believe I will try to stay on that dose to minimize side effects. Some constipation, difficult reaching orgasm, some night sweats and minor headaches. Oh, insomnia if I took it at night. I had samples of this medicine for 6 months but delayed starting it because of horror stories on the internet. Pain was ruining my life so this medicine seems to be the best option."

9 / 10
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  • brian
  • June 12, 2010

Cymbalta (duloxetine) "I have been using cymbalta for about 6 months now, I have severe leg pain caused by compartment syndrome and chronic low back pain and my md has me on cymbalta and lyrica for this pain and it has kept it under control, I still have to take percocet a few times a day but my pain is better with cymbalta and my depression has even gotten a lot better. Two birds with one stone type of deal."

8 / 10
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  • Becky...
  • July 3, 2011

Cymbalta (duloxetine) "I started taking Cymbalta in April 2011, and when I first started out on it I experienced, extreme tiredness, insomnia, dry mouth, constipation, hot flashes, strange dreams. I still get very odd sometimes disturbing dreams but I think a lot of it has to do with recent stresses in my life (grandma having a stroke, work stress) and still experience constipation, hot flashes, and night sweats but it's not the end of the world. It has so far been the only antidepressant medication that has really helped me and I have been on lots of different SSRI's and atypical antipsychotics. I have good and bad days like anyone does, but if I do get sad and cry it doesn't seem to last long. So in my opinion the benefits outweigh the side effects."

8 / 10
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  • Anonymous
  • Taken for less than 1 month
  • August 17, 2012

Cymbalta (duloxetine) "I had to stop taking Cymbalta after the first pill (30mg) caused side effects for me. Nausea, chills and hot flashes, cold sweats, no appetite, insomnia. Too much for me but I know this medicine has worked great for others, just not for me."

1 / 10
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  • Anonymous
  • February 1, 2012

Cymbalta (duloxetine) "It works great for my depression, but it does not help me at all with any of my arthritis pain. I have arthritis in my knees hands and spine. I also have sciatica and degenerative disc disease and it doesn't work for any of it."

5 / 10
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  • Anonymous
  • December 27, 2011

Cymbalta (duloxetine) "I have spinal stenosis in 2 levels of my lumbar spine and 3 bulging/protruding discs. I could hardly sit or walk for months. I was hoping for surgery just to ease the pain. I couldn't drive for longer than 15 minutes, couldn't exercise like I used to, could hardly work. My doctor put me on Cymbalta 2 weeks ago and within 10 days, almost all my pain is gone! I still have some numbness in my lower leg and foot but I am no longer taking Percocet and am weaning off the morphine for night time! Cymbalta gave me back my life! I hope it continues! Thank you for this wonderful medicine!"

10 / 10
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  • Anonymous
  • May 1, 2011

Cymbalta (duloxetine) "I have chronic pain from a broken arm and two surgeries last year. I've tried EVERYTHING - this is the only non-narcotic medicine that has worked for me. The only negative is that it doesn't have a generic equivalent and my insurance doesn't cover it. That's a pretty big negative. "

9 / 10
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  • Jmx
  • Taken for 6 months to 1 year
  • February 13, 2020

"Duloxetine did help with the pain in the beginning but a few months later at a 90mg dose and it's no longer helpful on its own. I now take it combination with slow release morphine. The combo works much better. I also use duloxetine for depression for which it is great."

6 / 10
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  • Jesus
  • Taken for less than 1 month
  • December 23, 2019

"My adverse side effects were nervousness, inbalance gait, headache, lethargy, insomia, diarrhea, heavy chest, shortness of breath. I literally felt like a zombie. That was my first dose. It resolved 32 hours later I felt normal again. This drug is AWFUL. It made me feel terrible all day long. I would not give this to an animal much less a human."

1 / 10
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  • Anonymous
  • October 12, 2012

Cymbalta (duloxetine) "I tried Cymbalta for chronic calf pain due to small fiber neuropathy. I did not experience brain zaps, night terrors or headaches but it did make me sleep a lot while i acclimated. I got up to 120mg/day but did not get any pain relief; still, it seemed to help with my attitude so i kept it at 60mg for a while. Ultimately I ended up getting better results from Pamelor."

4 / 10
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  • Anonymous
  • April 17, 2012

Cymbalta (duloxetine) "I'm actually writing this review on behalf of my wife. If you are bipolar, please stay away from this medicine. At first it seemed to help relieve the arthritis pain, but two months later the side effects became a nightmare and the pain increased threefold. It took another three months to clear it from her system, now she is doing much better but has short term memory issues. "

1 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.