Also known as: Adgan, Anergan 50, Antinaus 50, Phenadoz, Phenazine 50, Phenergan, Phenergan Fortis, Phenoject-50, Pro-Med, Promethegan, V-Gan-25, V-Gan-50
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
promethazine: Promethazine has worked wonders for me on many occasions when suffering from moderate to severe nausea. Due to the somewhat intense sedation at higher doses, I usually opt for Zofran (ondansetron) for mild nausea associated with the onset of a mild migraine. That being said, promethazine is the better option if you are already severely nauseous or vomiting. If taking it for the first time, be wary of doing anything that could be dangerous while being impaired, as it is notorious for being very sedating. Also, from personal experience, I learned that I cannot tolerate this medication IV. It was given to me as an opiate adjunct and caused me to become aggressive, disoriented, and extremely restless. Overall, I still recommend it.
promethazine: Promethazine syrup is what I started out with. It used to real good for me to take away nausea whenever I would experience. After having used it for over 10 years, I feel like it isn't working as effectively as it used to be. I just found out that it has alcohol in it, and I know longer feel comfortable using it. I also own it in pill form (50mg). The pill is very strong and I find that it leaves me feeling lethargic, dizzy, and it creates stomach upset. I don't understand how a pill that's supposed to help you when your nauseous and sick can actually make you feel worse. The suppositories work the best for me. I don't have any side effects from it. And unlike a pill, I don't have to worry a out it possibly coming back up again.
Phenergan (promethazine): I'm going through chemo (Taxol and Carboplatin) for ovarian cancer and Phenergan is great. I sometimes also take Zofran with it because they affect two totally different receptors causing the nausea and both together usually stops the ever present nausea.
Phenergan (promethazine): I have chronic pancreatitis and often have persistent nausea and vomiting. I have tried Zofran and a couple of other medications for this but none are as effective as Phenergan. Whether orally or I.V., it takes away the nausea. I have a GJ tube for enteral nutrition. Vomiting can cause the tube to twist and slide out of place so it's imperative to keep it under control. Phenergan does that for me. It also helps with the side effects from the painkillers I must take every day (oxycodone and Dilaudid). I don't know where I would be without it. Phenergan may be old school but it works for me better than any newer medicine.
14 users found this comment helpful.
promethazine: I have trouble with nausea and vomiting as well as severe coughing every spring or when the weather gets crazy. 6 years ago the doctor gave me some promethazine and after a few days the coughing a was just about gone. I tried everything and this really helped, but be prepared to sleep.
Phenergan (promethazine): Woke up with dizziness and terrible nausea. After 5 hours of dry heaving, went to doctor. One injection and nausea gone almost immediately. Slept for 3 hours, then ate dry bagel, chicken soup without any problems. Next day, eating normally but feel tired and a little "under the weather".
10 users found this comment helpful.
promethazine: I've been taking Phenergan for years now. It's a miracle medicine. I tried Zofran and it didn't work at all, in fact it made me get sicker. I suffer from extreme vomiting in all of my pregnancies. My dr. prescribed Phenergan to me and I'm so thankful for that. I LOVE this medicine.
promethazine: I suffer from severe anxiety, irritable bowel syndrome, and acid reflux disease. I have inflamed intestines quite often, which causes me to feel nauseous and on the verge of vomiting a few times a week. I got this medicine through an I.V. when I went into the Hospital for severe stomach pains, and was highly nauseous. It worked so well and relaxed me, I fell asleep for a few hours. They gave me a bottle and told me to use as needed. Now, when I have that feeling coming on, I'll pop one of those and relax & sleep it off. Always wake up feeling much better!
18 users found this comment helpful.
promethazine: I suffered from food poisoning, and was throwing up constantly. However after taking this medicine I was able to keep food down and it really helped with the vomiting. It is a powerful medicine and will make you sleepy. Use with caution during day time.
promethazine: I just had a major spine surgery (10-level spinal fusion with rods and screws) to fix my scoliosis. I was under general anesthesia for 5 hours. I'm almost 3 weeks post-op now, and this nausea medicine has been a lifesaver since day 1. I don't know if my problems are still from anesthesia, or from the post-op pain medicines but this nausea is awful and promethazine takes it right out. (Just be willing to nap).
Review by Anonymous (taken for less than 1 month):
Phenergan (promethazine): I have chronic pancreatitis and have severe nausea almost every day. My doctor tried many different medicines for nausea and vomiting over the 8 years I've been sick. Several years ago I tried Phenergen and had a severe allergic reaction. I later learned is called a tonic reaction.
promethazine: I am a male 50 years old and suffer from anxiety and depression. Out of the blue, I started experiencing severe nausea on a daily basis about 4 weeks ago. No matter what I tried or did, it hardly let up. It made me miserable, and due to the nausea and lack of appetite, I ended up losing about 10 pounds and I am slim already, so it greatly distressed me. I went to the ER twice, in early April and just recently. On the first trip they found an infection, treated it, but the nausea still continued afterward. On my second trip, they found NOTHING wrong with me and said I was probably creating it somehow with my mind. They put me on the Promethazine and for two days now no nausea.
12 users found this comment helpful.
Phenergan (promethazine): I have been using Phenergan to treat nausea for years. I have frequent and severe nausea associated with abdominal pain. It has been over three years and I am yet to get a diagnosis. I am grateful for this medicine. It is the only thing that stops the nausea. I would be crazy without this medicine! I was given Phenergan in the ER after I had a bad reaction to Zofran. It worked so well I asked the Doctor to send me home with a prescription for it. At my last ER visit they told me they were out of Phenergan and that it was in short supply. I was given Bentyl instead. That also gave me a bad reaction. I do without nausea medicine in the hospital if they do not have Phenergan.
16 users found this comment helpful.
Phenergan (promethazine): My wife has taken this medicine in pill form to combat nausea due to chemo, with no adverse side effects. Last week she was given a dose via her central line. She became psychotic and combative. Phenergan via IV was not good for her. Zofran is an excellent alternative.
11 users found this comment helpful.
promethazine: Promethazine is a histamine blocker. 25mg is an average dose for adults. Can also be taken with most pain medicines such as Vicodin, Toradol, tramadol, NSAID types (Advil, Celebrex, Aleve) please check with doctor before combining medicines. Makes you a little tired but not bad. Some people report promethazine also works for anxiety and stress.
Phenergan (promethazine): I had gall bladder surgery and got narcotics for pain afterwards. No matter what pain killer I got, they made me vomit even at half the dose. Ondansetron (Zofran) helped some but not fully. Once I got my first dose of Phenergan my nausea was completely gone. It made me very sleepy but I was very happy about. This was the best anti-nausea medication that I ever had!
17 users found this comment helpful.
promethazine: For the past 3 days I have been getting Promethazine by IV, this medication is the only one that works for me for nausea. I am having treatment for my Migraine called DHE given by IV. Promethazine works so good for the nausea. It does not make me sleepy and I have to be given it really diluted, I have small veins and it is very sore given by IV. I normally have a PICC line in and I have never felt this soreness before, and tonight I know the line is failing and tomorrow I will have to have yet another line placed.
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