Also known as: Adgan, Anergan 50, Antinaus 50, Phenadoz, Phenazine 50, Phenergan, Phenergan Fortis, Phenoject-50, Pro-Med, Promethegan, V-Gan-25, V-Gan-50
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
promethazine for Nausea/Vomiting: Promethazine has worked wonders for me on many occasions when suffering from moderate to severe nausea. Due to the somewhat intense sedation at higher doses, I usually opt for Zofran (ondansetron) for mild nausea associated with the onset of a mild migraine. That being said, promethazine is the better option if you are already severely nauseous or vomiting. If taking it for the first time, be wary of doing anything that could be dangerous while being impaired, as it is notorious for being very sedating. Also, from personal experience, I learned that I cannot tolerate this medication IV. It was given to me as an opiate adjunct and caused me to become aggressive, disoriented, and extremely restless. Overall, I still recommend it.
10 users found this comment helpful.
Review by Reservechic (taken for 10 years or more):
promethazine for Vertigo: The pill version does nothing for vertigo. In my opinion, it appears to make me feel more unbalanced and dizzy than without. The syrup form does provide some help when it comes to treating vertigo. But, it its effects aren't long lasting either.The suppository form does provide some help towards helping treat vertigo. For severe cases of vertigo, phenergan alone is not the best solution for such. I would only recommend using it if your vertigo is not severe.
promethazine for Nausea/Vomiting: Promethazine syrup is what I started out with. It used to real good for me to take away nausea whenever I would experience. After having used it for over 10 years, I feel like it isn't working as effectively as it used to be. I just found out that it has alcohol in it, and I know longer feel comfortable using it. I also own it in pill form (50mg). The pill is very strong and I find that it leaves me feeling lethargic, dizzy, and it creates stomach upset. I don't understand how a pill that's supposed to help you when your nauseous and sick can actually make you feel worse. The suppositories work the best for me. I don't have any side effects from it. And unlike a pill, I don't have to worry a out it possibly coming back up again.
promethazine for Motion Sickness: I own the tablets (50 mg), the syrup, and the suppositories. My longest experience has been with the syrup. I have been using the syrup for over 10 years for helping to control my motion sickness. Also, I have used it other times to help with stomach upset too. I started out taking 2 teaspoonfuls of the syrup and that worked great worked great for controlling my motion sickness. However, the longer I continued to take it, the higher of a dosage I found myself having to take for it to work for me. My doctor ended up increasing my dosage. I was prescribed the biggest bottle of this stuff that you can get. I saw alcohol listed as an ingredient. I didn't feel right using it anymore. I was prescribed the pill and suppositories to use instead.
Phenergan (promethazine) for Nausea/Vomiting: I'm going through chemo (Taxol and Carboplatin) for ovarian cancer and Phenergan is great. I sometimes also take Zofran with it because they affect two totally different receptors causing the nausea and both together usually stops the ever present nausea.
promethazine for Sedation: I'm 73 years old now and started taking Phenergan a long, long time ago. For the last 35 years I've taken a little more than 1/2 of a 25 mg tablet just about every night, about 3-4 hours before I want to go to sleep. Although I wake up about 3 times/night, I fall back to sleep easily and sleep for 8 to 9 hours. It is very "drying" but I consider this worth the good sleep. Often I combine it with 0.5 mg melatonin.
15 users found this comment helpful.
Phenergan (promethazine) for Nausea/Vomiting: I have chronic pancreatitis and often have persistent nausea and vomiting. I have tried Zofran and a couple of other medications for this but none are as effective as Phenergan. Whether orally or I.V., it takes away the nausea. I have a GJ tube for enteral nutrition. Vomiting can cause the tube to twist and slide out of place so it's imperative to keep it under control. Phenergan does that for me. It also helps with the side effects from the painkillers I must take every day (oxycodone and Dilaudid). I don't know where I would be without it. Phenergan may be old school but it works for me better than any newer medicine.
16 users found this comment helpful.
promethazine for Nausea/Vomiting: I have trouble with nausea and vomiting as well as severe coughing every spring or when the weather gets crazy. 6 years ago the doctor gave me some promethazine and after a few days the coughing a was just about gone. I tried everything and this really helped, but be prepared to sleep.
10 users found this comment helpful.
Phenergan (promethazine) for Nausea/Vomiting: Woke up with dizziness and terrible nausea. After 5 hours of dry heaving, went to doctor. One injection and nausea gone almost immediately. Slept for 3 hours, then ate dry bagel, chicken soup without any problems. Next day, eating normally but feel tired and a little "under the weather".
11 users found this comment helpful.
Phenergan (promethazine) for Opiate Adjunct: I have been taking Phenergan 25mg for yrs now. I have no problem with it and it works fine for me. This is for the lady that said she was 65yr old and her daughter had same reaction. You are severely allergic to Phenergan, do not take it any more, please. My wife was prescribed it for nausea and vomiting. She started taking it and every time she started feeling like throwing up by the time I made her go to the emergency room she was on the couch with her feet raised, I mean I had to put a cinder block under the end of the couch to raise it up enough for her. She could not stand up without throwing up and I had to hold her up to get to the bathroom. She was in the hospital for a week. Now she cannot look up without getting dizzy & going to pass out!
promethazine for Nausea/Vomiting: Made me sleep for an additional 10 hours at home. Did not relieve symptoms when I woke up. But maybe that is because my second dose should have been while I was sleeping.
promethazine for Nausea/Vomiting: I've been taking Phenergan for years now. It's a miracle medicine. I tried Zofran and it didn't work at all, in fact it made me get sicker. I suffer from extreme vomiting in all of my pregnancies. My dr. prescribed Phenergan to me and I'm so thankful for that. I LOVE this medicine.
promethazine for Nausea/Vomiting: I suffer from severe anxiety, irritable bowel syndrome, and acid reflux disease. I have inflamed intestines quite often, which causes me to feel nauseous and on the verge of vomiting a few times a week. I got this medicine through an I.V. when I went into the Hospital for severe stomach pains, and was highly nauseous. It worked so well and relaxed me, I fell asleep for a few hours. They gave me a bottle and told me to use as needed. Now, when I have that feeling coming on, I'll pop one of those and relax & sleep it off. Always wake up feeling much better!
20 users found this comment helpful.
promethazine for Nausea/Vomiting: I suffered from food poisoning, and was throwing up constantly. However after taking this medicine I was able to keep food down and it really helped with the vomiting. It is a powerful medicine and will make you sleepy. Use with caution during day time.
promethazine for Nausea/Vomiting: I just had a major spine surgery (10-level spinal fusion with rods and screws) to fix my scoliosis. I was under general anesthesia for 5 hours. I'm almost 3 weeks post-op now, and this nausea medicine has been a lifesaver since day 1. I don't know if my problems are still from anesthesia, or from the post-op pain medicines but this nausea is awful and promethazine takes it right out. (Just be willing to nap).
Review by Anonymous (taken for less than 1 month):
Phenergan (promethazine) for Nausea/Vomiting: I have chronic pancreatitis and have severe nausea almost every day. My doctor tried many different medicines for nausea and vomiting over the 8 years I've been sick. Several years ago I tried Phenergen and had a severe allergic reaction. I later learned is called a tonic reaction.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Data sources include Micromedex™ (updated Mar 13th, 2014), Cerner Multum™ (updated Apr 15th, 2014), Wolters Kluwer™ (updated Apr 3rd, 2014) and others. To view content sources and attributions, refer to our editorial policy.