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Promethazine User Reviews & Ratings (Page 4)

Brand names: Promethegan, Phenadoz, Antinaus 50, Anergan 50 Adgan

Promethazine has an average rating of 7.3 out of 10 from a total of 376 reviews on Drugs.com. 65% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Promethazine

  • Nk25
  • Taken for 1 to 6 months
  • January 26, 2020

For Sedation "They work great for me to get me to sleep. Drowsy within half an hour and asleep within an hour. Can’t take them everyday though as the grogginess and lethargy the next day is extreme. I’m so drowsy, feel weak and have a really dry mouth from them. I use them to treat insomnia that my depression meds cause."

7 / 10
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20 Report
  • Insom...
  • Taken for 2 to 5 years
  • September 24, 2019

For Sedation "Works totally like a light out. BUT I take prescription full dose... not OTC dose. Really hard to wake the next day. Have slept through the fire alarm. And yes I have extremely severe, hospitalised (at the time) sleep problems. Whilst it works, I hate the daytime grogginess. I still run twice a day etc, but the general ‘sleepiness’ annoys me."

8 / 10
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21 Report
  • Anony...
  • Taken for 5 to 10 years
  • March 24, 2021

Phenergan (promethazine) for Sedation "I have been taking these for almost 5 years what started as 1 x 10mg then turned into a huge dose. I have now dropped down to 3 x 10mg a night and have decided it’s time to go completely cold off them. I started taking these to sleep easier, as due to anxiety it was hard to fall asleep. I have made the decision to come off them as I was getting intense nightmares which made me afraid to fall asleep, my body was bruising extremely easily and my platelets were beginning to drop. Just be careful if you have an addictive personality"

6 / 10
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16 Report

Frequently asked questions

  • EmmyG
  • October 5, 2016

For Nausea/Vomiting "I have HG, and I've thrown up almost every hour in the hour. I was hospitalized twice before they finally gave me Promethazine. I wasn't able to keep down the oral medication, but I opted finally for the suppositories, and while it takes about 30 minutes for me to feel completely better, it's truly a lifesaver."

10 / 10
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29 Report
  • Scrach
  • Taken for 2 to 5 years
  • March 4, 2015

For Sedation "I started taking phenergen to assist with ongoing bad allergies (to dust mite and pollen) and found it very effective for this as well as guaranteeing me a good night sleep. I only take a 10mg dose about 1 hour before bed and no later than 8pm if I want to wake early for exercise before work. I find if I take it any later I am lethargic at 0530 and take a bit to get going. I have also used the syrup for my young boys as a rare sleep aid. Both my husband (who was prescribed it when he had an allergic reaction to penicillin) and eldest 5 yo are affected by this antihistamine/sleep aid. It makes them groggy and crabby the next day. My youngest (3yo) and I have only positive effects from it."

9 / 10
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33 Report

Are you taking this medicine?

  • Megan
  • Taken for less than 1 month
  • October 12, 2020

For Sedation "Horrible: Did its job for sedation but knocked me out for 16 hours after I had already had a full nights sleep. I ended up going to the hospital because it was such an adverse effect my neighbours couldn't wake me up properly when they came to check on me, I couldn't hear them calling me. The hospital added it to my allergy list. A few days after I started having extremely strong panic attacks, I had never had them before and put it down to Phenergan. I've read other reviews mentioning increased anxiety after taking it. It doesn't work for everybody."

2 / 10
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17 Report
  • Momma
  • February 15, 2017

Phenergan (promethazine) for Nausea/Vomiting "I do not know what I would do without promethazine! It helps a lot with my nausea which is very severe every day… It does not take it all away, I know… But it does help me enough I have been using this medicine for 11 years via IV centreline"

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  • Marts
  • Taken for 1 to 6 months
  • October 7, 2020

For Sedation "I started taking this a while back to help me sleep. It works in a funny way, doesn’t help me fall asleep, but once I’m asleep - it’s hard to wake up. I take half of a 25mg pill most times, if I take the full pill, I feel quite drowsy and extremely tired the next day. Maybe it’s cause I’m quite small though. Could quite literally sleep through the day. It surely does work though."

8 / 10
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  • barney
  • Taken for less than 1 month
  • May 30, 2021

For Nausea/Vomiting "I am pregnant and my doctor prescribed me promethazine for the nausea. I was a little apprehensive to take it because taking any medication while pregnant can be risky I feel. Anyway my nausea was so bad one day I decided to take one and it totally wiped me out. I was exhausted, and could have slept forever. At first I didn't want to take it again, but the next day I noticed my anxiety was calmer. I have severe PTSD and anxiety and upon finding out I was pregnant I stopped taking my meds for it (klonopin). They aren't safe, but I had been miserable since stopping. I just lived in complete panic/fear. I realized when I take just 1/4 of the promethazine tab my doc prescribed me for nausea my panic attack subsides and I can function a bit more normally. I only do this when I absolutely need it, but its a relief to me knowing that if I do panic I can at least take something to calm me down that my doctor approves of and is said to be safe for pregnant women."

8 / 10
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  • n8xwb
  • April 10, 2013

Phenergan (promethazine) for Nausea/Vomiting "Woke up with dizziness and terrible nausea. After 5 hours of dry heaving, went to doctor. One injection and nausea gone almost immediately. Slept for 3 hours, then ate dry bagel, chicken soup without any problems. Next day, eating normally but feel tired and a little 'under the weather'."

10 / 10
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35 Report
  • Szabina
  • November 28, 2011

Phenergan (promethazine) for Nausea/Vomiting "I had gallbladder surgery and got narcotics for pain afterwards. No matter what painkiller I got, they made me vomit even at half the dose. Ondansetron (Zofran) helped some but not fully. Once I got my first dose of Phenergan, my nausea was completely gone. It made me very sleepy, but I was very happy about it. This was the best anti-nausea medication that I ever had!"

10 / 10
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38 Report
  • Anonymous
  • December 30, 2010

Phenergan (promethazine) for Nausea/Vomiting "I have had stomach problems since I was a child, and so far, no doctor has been able to figure out what the problem is. The only relief I have gotten is from Phenergan (promethazine). I call it my 'miracle drug.' Even when already vomiting and nauseated, if I take 25 mg, in only about 15-20 minutes, I am relaxed and vomiting/nausea is gone. It does knock you out for a good bit, though, but if you have been up sick for a while, this will be a much-needed rest. Promethazine, you are my hero, and I love you."

10 / 10
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40 Report
  • Itsya...
  • Taken for 2 to 5 years
  • May 22, 2017

For Nausea/Vomiting "I was first given this medication after being admitted to the ER with a kidney infection, it is a literal miracle. I have an intense phobia of vomiting which gives me horrible anxiety anytime I feel nauseous (which is often with acid reflux and IBS) which makes the entire situation so much worse, but promethazine is an almost instant life saver. It did make me drowsy when I first started taking it, but that has lessened as time has gone by. It does take a while to completely work (30-60 mins depending on how amped up I am from anxiety) but as soon as I take it I know it's going to help and I am able to calm down and let it go to work. I can't imagine going back to a life where I missed out on work and events because of nausea."

10 / 10
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25 Report
  • Kez
  • Taken for 1 to 6 months
  • June 19, 2018

For Sedation "Having suffered torn cruciate ligament this couple of months, I've found phenergan to be a good sedative. I'm a bit worried about long term use, if anyone can help. I've been taking 25mg for the last 8 weeks to aide sleep. Any information would be greatly appreciated."

8 / 10
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22 Report
  • Rae
  • Taken for 2 to 5 years
  • November 23, 2019

For Nausea/Vomiting "I love promethazine. It works for me every time. I prefer to take 12.5 mg as the 25 mg make me sleep for darn near 13-15 hours every time, no matter how often I take them! I usually break my 25 in half if my Dr prescribes them instead of 12.5. Have been on this medication for 3 years and hopefully my body never builds up a tolerance to it. Works so well for my crohn's symptoms."

10 / 10
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  • jal
  • February 24, 2010

Phenergan (promethazine) for Motion Sickness "My husband and I have used Dramamine in the past for motion sickness while on our fishing boat. A 50 mg tablet will put us to sleep within 3 hrs after taking the pill. One time I could not drive home, I was falling asleep at the wheel. I went home and could not keep my eyes open. This time during our cruise, we saw a pharmacist on an island stop, and she gave us Phenergan and told us to take 1 15 mins. before going on a fishing charter. The pills worked wonderfully! We were out in really rough waters on a 30 ft. fishing boat for 4 hrs. Did not even get queasy at all! We were not even tired upon our return either. As a matter of fact, my husband said the pill made him hungry, and he ate more. Phenergan is wonderful! Throw away the Dramamine!"

9 / 10
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41 Report
  • Yatesie
  • Taken for 5 to 10 years
  • February 8, 2019

For Sedation "Being an insomniac on and off (maybe once or twice a week as needed) for as long as I can remember, I find the only thing that really helps is Promethazine. It doesn't make me feel nauseous the next day like a lot of other sleeping tablets, both OTC and script. It can take a few hours to work, so I need to take it at least a couple of hours before I want to go to sleep. There is one negative - nightmares. I haven't heard from many other people who have experienced the same thing, but let me tell you, they can be horrendous - the worst kind of terror you can imagine. The weird thing is, sometimes I get them, sometimes I don't! And the half life is 12-16hrs or something, so you can be quite fatigued the next day. Overall though, in spite of all it, it's a winner for me."

7 / 10
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  • EC94
  • Taken for less than 1 month
  • April 15, 2023

Phenergan (promethazine) for Sedation "After experiencing a severe onset of anxiety, I developed insomnia and couldn't sleep for over three weeks, remaining awake throughout the night. Additionally, I woke up with nausea and vomited for some days. I was prescribed 25mg to take before bed to help with sleep and nausea. The first time I took it, I slept for 12 hours! I felt drowsy the next morning but also refreshed and didn't wake up with nausea. The second time I took it, I slept for 8 hours and was still a little drowsy. Taking 25mg before bed definitely helps sedate me and improves my sleep throughout the night."

9 / 10
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  • MMK
  • December 2, 2019

For Sedation "I’ve been familiar with promethazine since I was a baby (now 27). Nowadays I work 1-3 x 12 hour overnight shifts per week and suffer terrible allergies. Before going on dymista for my hayfever I would take 10-25 mg of phenergan each night (or day depending if I’m working) with a 2mg SR melatonin and tbh, after a week of continuous use the phenergan no longer sedates me (down-regulated receptors I think?). However if I take a break from it, one 10mg will knock me out in an hour. I sleep deeply and feel groggy the next day. It also helps my anxiety and the nausea I sometimes get with melatonin. However there are side effects; headaches, fatigue, and because it relaxes the muscles in sleep, mild sleep apnoea. I sometimes wake from dreams, gagging/dry retching or gasping for air. I also suffer from VCD and find I’m more susceptible to attacks when regularly taking phenergan. I read somewhere than neuroleptic drugs can do this. So now I take it if needed."

8 / 10
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17 Report
  • Metha...
  • Taken for 2 to 5 years
  • April 8, 2015

For Nausea/Vomiting "Promethazine is a godsend to me. I'm on many other medications, which get me sick every morning, feeling nausea/vomiting, dizziness, etc. Promethazine takes all that away from me, and I love it! I really recommend this drug for people who get morning sickness or are RX'd a strong narcotic (Oxycodone, Morphine, Methadone, etc.), it helps and takes away the bad side effects of the narcotic. It's RX'd as an opiate adjunct. Works wonders."

10 / 10
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28 Report
  • Ghand
  • August 28, 2015

Phenergan (promethazine) for Sedation "I was prescribed this for my 6 yr old daughter to help her sleep. I've only been using it a couple of nights but it doesn't seem to be working. I am giving her the 3x5ml dose and giving her it at 6pm and up to now she is still not going to sleep before 11pm. Am I not giving her enough or not giving it enough time to work? Advice greatly appreciated! Thanks"

3 / 10
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27 Report
  • volca...
  • Taken for 1 to 2 years
  • March 6, 2017

For Nausea/Vomiting "I suffer from stomach ulcers and a ton of other stomach problems, and I also have crippling anxiety and depression so I stay nauseated most of the time. It also doesn't help that I have a fear of vomiting. When my dad was still alive (he had cancer) he told me to try promethazine so when I went to the doctor I asked him about it and he told me that it would be a good medication for me. It does make me a bit drowsy but I don't mind since I have insomia anyways. This medication has made my life so much better, I don't know what I'd do without it!"

10 / 10
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23 Report
  • Littl...
  • March 30, 2012

Phenergan (promethazine) for Nausea/Vomiting "I have been using Phenergan to treat nausea for years. I have frequent and severe nausea associated with abdominal pain. It has been over three years, and I am yet to get a diagnosis. I am grateful for this medicine. It is the only thing that stops the nausea. I would be crazy without this medicine! I was given Phenergan in the ER after I had a bad reaction to Zofran. It worked so well, I asked the doctor to send me home with a prescription for it. At my last ER visit, they told me they were out of Phenergan and that it was in short supply. I was given Bentyl instead. That also gave me a bad reaction. I do without nausea medicine in the hospital if they do not have Phenergan."

10 / 10
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33 Report
  • Mano
  • Taken for 1 to 2 years
  • August 6, 2018

For Opiate Adjunct "After fracturing my clavicle in six places in a football scrum, I have suffered chronic pain. One of the fractures (where bone is no longer present) never repaired itself. I am currently on Oxycodone 20mg four times a day, Codeine 60mg four times a day and Lyrica (Pregabalin) 300mg twice a day. Was told by my Specialist to go to the chemist and get a box of Promethazine and take 25mg-50mg four times a day to see if it potentiated my analgesia. My goodness has it been a life changer. I am almost at a pain score of 0. Also, given that it is an antihistamine, it removes the itch associated with opiate use. A solid 10/10."

10 / 10
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  • A t g
  • Taken for less than 1 month
  • February 28, 2022

Phenergan (promethazine) for Nausea/Vomiting "Do not use this medication for anyone over 60. My mother was given this in the hospital for mild nauseous feeling. I think they thought she would be sedated by it. She is elderly. This drug put her into a terrible state of hallucinations delirium and all around restlessness for about 8 hours. It’s awful. She would have been better off with tums. Be aware of all the side affects."

1 / 10
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10 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.