Generic Name: fosinopril (fos-IN-oh-pril)
Brand Name: Monopril
Fosinopril may cause injury or death to the fetus if taken during pregnancy. If you think you may be pregnant, contact your doctor right away. If you are planning to become pregnant, talk with your doctor about other treatment options.
Fosinopril is used for:
Treating high blood pressure alone or with other medicines. It is used along with other medicines to manage heart failure. It may also be used for other conditions as determined by your doctor.
Fosinopril is an angiotensin-converting enzyme (ACE) inhibitor. It works by relaxing blood vessels. This helps to lower blood pressure.
Do NOT use fosinopril if:
- you are allergic to any ingredient in fosinopril or to other ACE inhibitors (eg, lisinopril)
- you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or unusual hoarseness), including angioedema caused by treatment with an ACE inhibitor
- you are pregnant
- you are also taking aliskiren and you have either diabetes or kidney problems
Contact your doctor or health care provider right away if any of these apply to you.
Before using fosinopril:
Some medical conditions may interact with fosinopril. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are able to become pregnant
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of heart problems (eg, heart failure, aortic stenosis), blood vessel problems, blood flow problems, bone marrow problems, diabetes, or kidney or liver problems
- if you have a history of stroke, recent heart attack, or kidney transplant
- if you have an autoimmune disease (eg, rheumatoid arthritis, lupus, scleroderma)
- if you are dehydrated or have low blood volume
- if you have high blood potassium levels, low blood sodium levels, or are on a low-salt (sodium) diet
- if you are receiving treatments to reduce sensitivity to bee or wasp stings
- if you are having dialysis or apheresis, or are scheduled to have surgery or receive anesthesia
- if you are taking another medicine to treat high blood pressure
Some MEDICINES MAY INTERACT with fosinopril. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood pressure may be increased
- Everolimus or sirolimus because the risk of angioedema may be increased
- Eplerenone, potassium-sparing diuretics (eg, spironolactone, triamterene), potassium supplements, or trimethoprim because the risk of high blood potassium levels may be increased
- Aliskiren or angiotensin receptor blockers (eg, losartan) because the risk of certain side effects (eg, serious kidney problems, high blood potassium levels, low blood pressure) may be increased
- Insulin, sulfonylureas (eg, glipizide), or other oral diabetes medicines (eg, metformin) because the risk of low blood sugar may be increased
- Certain gold-containing medicines (eg, auranofin, sodium aurothiomalate) because flushing, nausea, vomiting, and low blood pressure may occur
- Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen, indomethacin, celecoxib) because they may decrease fosinopril's effectiveness and the risk of kidney problems may be increased
- Lithium because the risk of its side effects may be increased by fosinopril
This may not be a complete list of all interactions that may occur. Ask your health care provider if fosinopril may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use fosinopril:
Use fosinopril as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take fosinopril by mouth with or without food.
- Do not take an antacid that has aluminum, magnesium, or simethicone in it within 2 hours before or 2 hours after you take fosinopril.
- Use fosinopril on a regular schedule to get the most benefit from it. Taking fosinopril at the same time each day will help you remember to take it.
- Continue to use fosinopril even if you feel well. Do not miss any doses.
- If you miss a dose of fosinopril, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use fosinopril.
Important safety information:
- Fosinopril may cause dizziness, light-headedness, or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use fosinopril with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Fosinopril may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Fosinopril may cause a serious side effect called angioedema. The risk may be higher in black patients. Contact your doctor at once if you develop swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or unusual hoarseness.
- Fosinopril may not work as well in black patients. They may also be at greater risk of side effects. Contact your doctor if your symptoms do not improve or if they become worse.
- Fosinopril may cause a dry, unproductive cough. If caused by fosinopril, this symptom usually stops after treatment with fosinopril is stopped.
- Dehydration, excessive sweating, vomiting, or diarrhea may increase the risk of low blood pressure. Contact your health care provider at once if any of these occur.
- Fosinopril may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to fosinopril. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Rarely, fosinopril may lower the ability of your body to fight infection. This risk may be greater if you have certain other health problems (eg, kidney problems, collagen vascular disease). Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
- Check with your doctor before you use a salt substitute or a product that has potassium in it.
- Tell your doctor or dentist that you take fosinopril before you receive any medical or dental care, emergency care, or surgery.
- Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
- If you have high blood pressure, do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines. Contact your doctor if you have any questions or concerns.
- Diabetes patients - Fosinopril may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Fosinopril may interfere with certain lab tests, including certain tests for digoxin blood level. Be sure your doctor and lab personnel know you are taking fosinopril.
- Lab tests, including blood pressure, blood electrolyte levels, heart function, or kidney or liver function, may be performed while you use fosinopril. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use fosinopril with caution in the ELDERLY; they may be more sensitive to its effects.
- Fosinopril should be used with extreme caution in CHILDREN younger than 6 years old and in children weighing less than 110 pounds (50 kg); safety and effectiveness in these children have not been confirmed.
- PREGNANCY AND BREAST-FEEDING: Fosinopril may cause birth defects or fetal death if you take it while you are pregnant. If you think you may be pregnant, contact your doctor right away. Fosinopril is found in breast milk. Do not breast-feed while taking fosinopril.
Possible side effects of fosinopril:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Cough; dizziness; nausea.
Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the eyes, mouth, face, lips, throat, or tongue; unusual hoarseness); burning, numbness, or tingling; chest, jaw, or arm pain; confusion; decreased urination; fast, slow, or irregular heartbeat; memory problems; mental or mood changes; muscle pain or cramping; one-sided weakness; shortness of breath; slurred speech; stomach pain (with or without nausea or vomiting); sudden, severe nausea or vomiting; swelling; symptoms of infection (eg, fever, chills, persistent sore throat); symptoms of liver problems (eg, dark urine, loss of appetite, pale stools, stomach pain, yellowing of the skin or eyes); symptoms of low blood pressure (eg, fainting, severe dizziness, light-headedness); tremors; unusual sweating; vision changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include fainting; severe dizziness or light-headedness.Proper storage of fosinopril:
Store fosinopril at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep fosinopril out of the reach of children and away from pets.
- If you have any questions about fosinopril, please talk with your doctor, pharmacist, or other health care provider.
- Fosinopril is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take fosinopril or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about fosinopril. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to fosinopril. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using fosinopril.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about fosinopril
- Other brands: Monopril