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Cefpodoxime

Pronunciation

Generic Name: cefpodoxime (SEF-poe-DOX-eem)
Brand Name: Vantin

Cefpodoxime is used for:

Treating mild to moderate infections caused by certain bacteria.

Cefpodoxime is a cephalosporin antibiotic. It works by interfering with the formation of the bacteria's cell wall so that the wall ruptures, resulting in the death of the bacteria.

Do NOT use cefpodoxime if:

  • you are allergic to any ingredient in cefpodoxime or to any other cephalosporin antibiotic (eg, cephalexin, cefprozil)

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: The Shocking Truth About Antibiotic Resistance

Before using cefpodoxime:

Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diarrhea, a stomach or intestinal infection, or a blood clotting problem
  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to a penicillin antibiotic (eg, amoxicillin) or other beta-lactam antibiotic (eg, imipenem)

Some MEDICINES MAY INTERACT with cefpodoxime. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Aminoglycosides (eg, gentamicin), cyclosporine, or diuretics (eg, furosemide, hydrochlorothiazide) because the risk of side effects on the kidney may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if cefpodoxime may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use cefpodoxime:

Use cefpodoxime as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take cefpodoxime by mouth with food.
  • Cefpodoxime works best if it is taken at the same time each day.
  • To clear up your infection completely, take cefpodoxime for the full course of treatment. Keep taking it even if you feel better in a few days.
  • Cefpodoxime should not be given within 2 hours of antacids or H2 antagonists (eg, famotidine).
  • If you miss a dose of cefpodoxime, take it as soon as possible. If it is almost time for your next dose, skip the missed dose, and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use cefpodoxime.

Important safety information:

  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Cefpodoxime only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Be sure to use cefpodoxime for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of cefpodoxime may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed while you use cefpodoxime. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using cefpodoxime while you are pregnant. The medicine is found in breast milk. Do not breast-feed while taking cefpodoxime.

Possible side effects of cefpodoxime:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; headache; loose stools; nausea; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; seizures; severe diarrhea; skin rash; stomach pain/cramps; vaginal irritation or discharge.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include abdominal pain; diarrhea; headache; nausea; seizures; vomiting.

Proper storage of cefpodoxime:

Store cefpodoxime at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 to 86 degrees F (15 to 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Replace cap securely after each opening. Keep cefpodoxime out of the reach of children and away from pets.

General information:

  • If you have any questions about cefpodoxime, please talk with your doctor, pharmacist, or other health care provider.
  • Cefpodoxime is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take cefpodoxime or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about cefpodoxime. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to cefpodoxime. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using cefpodoxime.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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