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Intuniv (guanfacine): Clinical Effectiveness

Intuniv (guanfacine) clinical effectiveness to help manage the symptoms of childhood ADHD.

Video transcript

Hello and welcome to "VideoScript", presented by

Today in the second of three presentations, we continue reviewing Intuniv, also known as guanfacine. Intuniv is an FDA-approved medication used as part of a treatment program to help manage the symptoms of ADHD in children.

Intuniv is in a class of medications known as selective alpha-2a adrenergic agonists.

Intuniv is not a stimulant medication or a controlled substance, and how it works in ADHD is not fully known.

In clinical trials, Intuniv has been shown to be superior to a placebo, or sugar pill, when evaluating treatment effect on the core symptoms of ADHD.

A 44% improvement in ADHD scores was seen in the Intuniv group compared to a 23% improvement in the placebo group.

Parents also reported significant improvements in their child’s ADHD symptoms.

Clinical trials show that Intuniv can be used with a stimulant, such as long-acting methylphenidate, if the stimulant alone is not sufficient for ADHD treatment.

Also, Intuniv can be given once a day, which may offer an advantage in school-aged children.

Thank you for joining us at for a brief review of Intuniv. Please refer to our patient and professional information, drug interaction checker, and additional tools on

Patients with a concern about the use of Intuniv should consult with their health care provider.

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