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Uniprim Oral Powder (Apple Flavoured) (Canada)

This page contains information on Uniprim Oral Powder (Apple Flavoured) for veterinary use.
The information provided typically includes the following:
  • Uniprim Oral Powder (Apple Flavoured) Indications
  • Warnings and cautions for Uniprim Oral Powder (Apple Flavoured)
  • Direction and dosage information for Uniprim Oral Powder (Apple Flavoured)

Uniprim Oral Powder (Apple Flavoured)

This treatment applies to the following species:
Company: Neogen

Trimethoprim and Sulfadiazine


For Veterinary Use Only

DIN 02241375

Active Ingredients

Each g contains 67 mg Trimethoprim USP and 333 mg Sulfadiazine USP.


UNIPRIM Oral Powder contains trimethoprim, a synthetic antibacterial, and sulfadiazine, a sulfonamide in combination at a ratio of 1:5. The two components of UNIPRIM Oral Powder produce a sequential blockade of bacterial metabolism, giving a level of activity many times greater than that obtained from either drug alone.

UNIPRIM Oral Powder is a dosage form containing 6.7% w/w trimethoprim USP and 33.3% w/w sulfadiazine USP in an inert carrier.

UNIPRIM Oral Powder provides effective antibacterial activity against a wide range of infections caused by Gram-positive and Gram-negative bacteria.

Pathogenic bacteria which can cause infection in the horse and are sensitive to UNIPRIM Oral Powder in vitro include:

Very sensitive organisms:

Escherichia coli

Shigella equirulis

Salmonella spp.

Pasteurella spp.

Haemophilus spp.

Sensitive organisms:

Streptococcus spp.

Staphylococcus spp. (including penicillinase-producing organisms)

Klebsiella spp.

Proteus spp.

Corynebacterium spp.

Bordetella spp.

Actinobacillus spp.

Listeria monocytogenes

Non-sensitive organisms:

Pseudomonas aeruginosa*

Leptospira spp.

*usually non-sensitive

Uniprim Oral Powder (Apple Flavoured) Indications

UNIPRIM Oral Powder is an antibacterial indicated in horses for the treatment of the following infections when caused by susceptible organisms:

- Acute strangles

- Other respiratory infections

- Wound and postoperative infections

Uniprim Oral Powder (Apple Flavoured) Dosage And Administration

The usual dose of UNIPRIM Oral Powder for horses, ponies and foals is 3.75 g per 50 kg. The content of two 32 cc scoops (37.5 g) is sufficient to treat 500 kg live weight. This dose provides 30 mg/kg bodyweight of actives daily.

The powder should be mixed with a small amount of palatable feed. UNIPRIM Oral Powder is palatable but if the treated horse does not consume the medication in total, then parenteral or individual oral dosage with an alternative product should be considered.

Treatment should be given once daily until 2-3 days after the animal becomes asymptomatic. The usual course of treatment is for not longer than 7 consecutive days.


UNIPRIM Oral Powder should not be used in horses showing marked liver parenchymal damage or blood dyscrasias, nor in those with a history of sulfonamide sensitivity.

Uniprim Oral Powder (Apple Flavoured) Cautions

UNIPRIM Oral Powder should not be administered to pregnant mares as the effects of this product, when used as recommended, on the unborn foal have not been determined.


Treated animals must not be slaughtered for use in food for at least 7 days after the latest treatment with this drug. Keep out of reach of children.

Adverse Reactions

Individual animal hypersensitivity may result in local or generalised reactions, sometimes fatal. Anaphylactoid reactions, although rare, may also occur. Horses may develop diarrhea during trimethoprim/sulfadiazine treatment, which could be fatal. If fecal consistency changes during trimethoprim/sulfadiazine therapy, discontinue treatment immediately and contact your veterinarian.


Store between 2° and 35° C.


400 g jars


Manufactured by: Neogen Corporation, 944 Nandino Blvd., Lexington, KY 40511 USA

Distributed by: BIO AGRI MIX LP, PO Box 399, Mitchell, Ontario, Canada, N0K 1N0

Net Contents:

Item No.


400 grams



Rev. 06/15

CPN: 1269003.2

Distributed by BIO AGRI MIX LP
Telephone:   519-348-9865
Order Desk:   800-265-1763
Technical Information:   226-303-2503
Fax:   519-348-4100
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