ProSystem RCEThis page contains information on ProSystem RCE for veterinary use.
The information provided typically includes the following:
- ProSystem RCE Indications
- Warnings and cautions for ProSystem RCE
- Direction and dosage information for ProSystem RCE
ProSystem RCEThis treatment applies to the following species:
Porcine Rotavirus Vaccine
Modified Live Virus
Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid
ProSystem RCE Indications
This product contains two major rotavirus serotypes, four major Escherichia coli pilus antigens (K88, K99, F41 and 987P) and Clostridium perfringens Type C (CpC) toxoid. When used in healthy pregnant swine, the rotavirus, E. coli K88, K99, F41 pilus antigens and CpC toxoid aid in prevention of rotaviral diarrhea, colibacillosis and enterotoxemia in their nursing piglets. Additionally, the E coli 987P antigen aids in the prevention of mortality and reduction of clinical disease caused by this serotype in nursing piglets.
SAFETY AND EFFICACY: Safety and efficacy of the Rotavirus vaccine and C. perfringens-E. coli bacterin-toxoid have been extensively evaluated in experimental tests and in field trials conducted by veterinarians. Both fractions have been demonstrated to be safe for pregnant swine and laboratory animals. Pregnant sows and gilts, when vaccinated intramuscularly with rotavirus, subsequently develop high persisting levels of rotavirus antibody in their milk, thereby aiding in the control of rotaviral diarrhea in their nursing pigs. Oral vaccination of sows and gilts with ProSystem® TGE/Rota (Porcine Rotavirus-Transmissible Gastroenteritis vaccine) also has been recommended as a means of reducing virus shedding and inducing high persisting levels of milk antibody. Either approach is satisfactory for prevention of rotaviral diarrhea in nursing pigs. Vaccination of pregnant swine with C. perfringens Type C toxoid and four major E. coli pilus antigens (K88, K99, F41 and 987P) also greatly reduced the incidence and severity of enterotoxemia and colibacillosis in their litters in experimental tests. Baby pigs are protected from rotaviral diarrhea, enterotoxemia and colibacillosis by receiving colostral and milk antibodies from vaccinated dams. Therefore, it is mandatory for both viral and bacterial passive immunity that sows and gilts are lactating and baby pigs are nursing.
DOSAGE AND DIRECTIONS: Shake bacterin-toxoid well. Restore accompanying vial of desiccated virus vaccine with 10-15 mL bacterin-toxoid and then transfer rehydrated vaccine back into plastic bacterin-toxoid bottle. Shake well, immediately inject a 2 mL dose intramuscularly into healthy pregnant swine at 5 weeks and again at 2 weeks before farrowing. In subsequent farrowings, inject one 2 mL dose 2 weeks before farrowing.
ProSystem RCE Caution
Store in the dark at 2° to 7°C (35° to 45°F). Do not freeze. Use immediately after reconstitution; do not save partial contents; burn both containers and all unused contents. Use only in healthy pregnant swine. Do not vaccinate within 21 days of slaughter. Conditions which interfere with lactation adversely affect immunity in baby pigs. If allergic reaction occurs, treat with epinephrine. Contains gentamicin, polymyxin B and thimerosal as preservatives.
FOR ANIMAL USE ONLY
Intervet Inc., Merck Animal Health, division of Intervet Inc., Omaha, NE 68103 USA
U.S. Veterinary License No. 165A
For patent information:
NAC No.: 1047368.3
2 GIRALDA FARMS, MADISON, NJ, 07940
|Technical Service (Companion Animal):||800-224-5318|
|Technical Service (Livestock):||800-211-3573|
|Every effort has been made to ensure the accuracy of the ProSystem RCE information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.|
Copyright © 2016 North American Compendiums. Updated: 2016-09-30