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Nuplura PH + 3

This page contains information on Nuplura PH + 3 for veterinary use.
The information provided typically includes the following:
  • Nuplura PH + 3 Indications
  • Warnings and cautions for Nuplura PH + 3
  • Direction and dosage information for Nuplura PH + 3

Nuplura PH + 3

This treatment applies to the following species:
Company: Elanco (Farm Animal)

Bovine Rhinotracheitis-Virus Diarrhea Vaccine, Modified Live Virus, Mannheimia Haemolytica Bacterial Extract-Toxoid

For Use In Animals Only

Nuplura PH + 3 Indications

This product has been shown to be effective for the vaccination of healthy cattle, 3 months of age and older, against respiratory disease caused by Mannheimia haemolytica and against disease caused by infectious bovine rhinotracheitis and bovine viral diarrhea virus (Type 1 and Type 2). The duration of immunity for this product has not been established. For more information regarding efficacy and safety data, see

A single dose has been shown to be effective against respiratory disease caused by M. haemolytica as early as 10 days after administration. Safety has been demonstrated in calves 28 days of age and older.


Contains Mannheimia haemolytica Outer Membrane Proteins and recombinant leukotoxoid. Modified Live Bovine Rhinotracheitis Virus and cytopathic BVD Types 1 and 2 isolates.

ADJUVANT: Emulsigen® D.

Directions For Use

Rehydrate the desiccated vial with accompanying diluent (NUPLURA PH PCN 7906.R0). Shake well before using. Administer a 2 mL dose subcutaneously following Beef Quality Assurance guidelines. The need for annual booster vaccinations has not been established for this product. For advice on revaccination frequency, in general or in the face of maternal antibody, stress, or a disease exposure, consultation with a veterinarian is recommended.


Do not use in pregnant cows or in calves nursing pregnant cows. This product has not been tested in pregnant animals. Store out of direct sunlight at 2° to 8°C (35° to 46°F). DO NOT FREEZE. Do not mix with other products, except as specified on the label. Use entire contents when first opened. Inactivate all unused contents before disposal. Do not vaccinate within 60 days before slaughter. Transient injection site swelling may occur. In case of anaphylactic reaction treat with Epinephrine. In case of human exposure, contact a physician. Contains thimerosal and gentamicin as preservatives.

VLN/PCN: 196/4X29.R0

Elanco US Inc., Fort Dodge, IA 50501


NUPLURA, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates.

10 Doses

20 mL


50 Doses

100 mL


CPN: 1114121.0

Distributed by ELANCO US, INC.
Customer Service:   317-276-1262
Technical Service:   800-428-4441
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