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Meloxidyl 20 mg/mL (Canada)

This treatment applies to the following species:
Company: Ceva Animal Health

Meloxicam Injection, Mfr. Std.

Veterinary Use Only


DIN 02468182

Each mL contains 20 mg meloxicam and 150 mg ethanol, as preservative.


Nonsteroidal anti-inflammatory drug (NSAID).

Meloxidyl 20 mg/mL Indications

Cattle: As an aid in improving appetite and weight gain when administered at the onset of diarrhoea, in combination with oral rehydration therapy, in calves over one week of age. For relief of pain following de-budding of horn buds in calves less than 3 months of age. For the symptomatic treatment of inflammation and pain associated with acute clinical mastitis. For the reduction of pain associated with abdominal surgery such as caesarean section.

Sheep: For single dose use in sheep and lambs 14 days of age or older for the alleviation of pain and inflammation.

Swine: For use in non-infectious locomotor disorders to reduce the symptoms of lameness and inflammation.

Dosage and Administration

Cattle: Single subcutaneous or intravenous injection of 0.5 mg meloxicam/kg body weight (2.5 mL/100 kg). For reduction in pain associated with abdominal surgery administer 10 to 20 minutes before the painful procedure.

Sheep: Single subcutaneous injection administered 15-30 minutes prior to painful procedure. Inject the product high on the neck behind the ear at a dose of 1.0 mg meloxicam/kg body weight (1.0 mL/20 kg).

Swine: Single intramuscular injection at a dosage of 0.4 mg meloxicam/kg body weight (2.0 mL/100 kg). If required, a second administration of meloxicam can be given after 24 hours.

The 50 mL and 100 mL vial may be punctured a maximum of 250 times.


Do not use in animals suffering from gastrointestinal disorders such as irritation and hemorrhage, impaired hepatic, cardiac or renal function and hemorrhagic disorders or where there is individual hypersensitivity to the product.

Do not administer concurrently with steroidal, other nonsteroidal anti-inflammatory drugs or with anti-coagulant agents.

Concomitant use of NSAIDs with aminoglycoside antimicrobials in very young animals may result in renal toxicity.


Do not use in bulls, rams or boars intended for breeding. Avoid use in very severely dehydrated, hypovolaemic or hypotensive animals which require parenteral rehydration, as there may be a potential risk of increased renal toxicity.

Use of anti-inflammatories in very young or debilitated animals may involve additional risk.

The safety of meloxicam has not been evaluated in lambs less than 14 days of age.

The safety of meloxicam in breeding and pregnant sows has not been fully evaluated.

Available data suggest that meloxicam has no harmful effects in the second and third trimester of pregnancy. However the potential effects of meloxicam on imminent parturition have not been evaluated. This product can be used in lactating sows.

Treatment of cows with meloxicam before abdominal surgery reduces post-operative pain. An anti-inflammatory alone will not provide adequate pain relief during the surgical procedure. To obtain adequate pain relief during surgery co-medication with an appropriate analgesic is recommended.


Treated animals must not be slaughtered for use in food for at least 20 days for cattle, 11 days for sheep and 5 days for swine after the latest treatment with this drug. Milk taken from treated cows during treatment and within 96 hours after the latest treatment with this drug must not be used in food. Do not use in lactating ewes or pregnant ewes within 11 days of lambing where milk may be used or processed for human consumption. Do not use in calves to be processed for veal as a withdrawal period has not been established for pre-ruminating calves.

Keep out of reach of children.

Adverse Reactions

Transient, slight injection site swellings may occasionally be seen following subcutaneous injection and intravenous injection.

In very rare cases, anaphylactoid reactions may occur and should be treated symptomatically.


Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class which acts by inhibition of prostaglandin synthesis, thereby exerting anti-inflammatory, analgesic and anti-pyretic properties. Meloxicam also has anti-endotoxic properties because it has been shown to inhibit production of thromboxane B2 induced by E. coli endotoxin administration in calves.


The acute oral toxicity (LD50) of meloxicam assessed in rats, mini-pigs, mice and rabbits was >80 mg/kg, 1600 mg/kg, 470 mg/kg and 320 mg/kg, respectively. Repeated dose toxicity studies in rats, mice and mini-pigs demonstrated that the primary target organs for toxicity were the gastrointestinal tract (pyloric, duodenal and small intestine ulceration) and kidneys (scarring, necrosis and pyelonephritis).


Store at or below 25°C. Keep from freezing. Use within 28 days following first use, then discard any remaining vial contents.


Meloxidyl® 20 mg/mL Solution for Injection is available in 50 and 100 mL multi-dose vials.

Ceva Animal Health Inc., 150 Research Lane, Suite 225, Guelph ON N1G 4T2



® Meloxidyl is a registered trade mark of Ceva Santé Animale, France

CPN: 1221131.2

Telephone:   519-650-9570
Toll-Free:   800-510-8864
Fax:   519-650-9576
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