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Master Guard 10 HB

This page contains information on Master Guard 10 HB for veterinary use.
The information provided typically includes the following:
  • Master Guard 10 HB Indications
  • Warnings and cautions for Master Guard 10 HB
  • Direction and dosage information for Master Guard 10 HB

Master Guard 10 HB

This treatment applies to the following species:
Company: Elanco US

Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine, Modified Live and Killed Virus

Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin

from the Signature cell line®

Master Guard 10 HB Indications

This product has been shown to be effective for the vaccination of healthy cattle 5 months of age or older, including pregnant cows, against infectious bovine rhinotracheitis virus (IBR), bovine virus diarrhea virus Type I (BVD), bovine virus diarrhea virus Type II (BVD), bovine parainfluenza3 virus (PI3), bovine respiratory syncytial virus (BRSV) and against Leptospira borgpetersenii serovar hardjo-bovis and Leptospira canicola-grippotyphosa-hardjo-icterohaemorrhagiae-pomona. The duration of immunity has not been determined. For more information regarding efficacy and safety data, see

This product contains BVD Type I and BVD Type II.

DIRECTIONS AND DOSAGE: Rehydrate the desiccated vial with accompanying diluent and shake well. Inject 3 mL subcutaneously or intramuscularly using aseptic technique. Repeat the dose in 14 to 28 days. The need for annual booster vaccinations has not been established for this product. The presence of maternal antibody is known to interfere with the development of active immunity in calves and additional boosters will be required in most young animals. For advice on revaccination frequency, consult your veterinarian. Do not mix with other products, except as specified on the label.

CAUTIONS: Fetal health risks associated with the vaccination of pregnant animals with this vaccine cannot be unequivocally determined during clinical trials conducted for licensure. Appropriate strategies to address the risks associated with vaccine use in pregnant animals should be discussed with a veterinarian. Failure to follow label directions may result in abortions. Store at 35-46°F (2-8°C). DO NOT FREEZE. Use entire contents when first opened. Do not vaccinate within 21 days of slaughter. In case of human exposure, contact a physician. Inactivate unused contents before disposal. Allergic reactions may follow the use of vaccines; ANTIDOTE: Epinephrine. Contains gentamicin and thimerosal as a preservative.


Manufactured by:

Diamond Animal Health, Inc., Des Moines, Iowa 50327 U.S.A.

U.S. Veterinary License No. 213

Product Code No. 4469.20

Distributed by:

Elanco US Inc., Greenfield, IN 46140 U.S.A.


Master Guard, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates.

© 2021 Elanco or its affiliates

10 Doses

30 mL

03586 SH101815A

25 Doses

75 mL

03587 SH101815B

CPN: 1131142.0

Customer Service:   317-276-1262
Technical Service:   800-428-4441
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