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Ingelvac ERY-ALC (Canada)

This page contains information on Ingelvac ERY-ALC for veterinary use.
The information provided typically includes the following:
  • Ingelvac ERY-ALC Indications
  • Warnings and cautions for Ingelvac ERY-ALC
  • Direction and dosage information for Ingelvac ERY-ALC

Ingelvac ERY-ALC

This treatment applies to the following species:
Manufacturer: Boehringer

Erysipelothrix Rhusiopathiae Vaccine

Avirulent Live Culture

For use in swine only

Ingelvac ERY-ALC Indications

For the vaccination of healthy, susceptible swine 8 weeks of age or older as an aid in the prevention of disease caused by Erysipelothrix rhusiopathiae (erysipelas).

Description

Ingelvac® ERY-ALC is a frozen vaccine prepared from a specially selected strain of Erysipelothrix rhusiopathiae. The duration of immunity is at least 128 days.

In a duration of immunity study, 19 of 21 pigs (90%, p<0.0001) dosed orally with a single dose of Ingelvac® ERY-ALC at an average of 52 days of age were completely protected when challenged with virulent erysipelas at 184 days of age. Sixteen of 21 pigs (76%, p<0.0001) dosed orally with a single dose of Ingelvac® ERY-ALC at an average of 32 days of age were completely protected when challenged at 163 days of age. All nonvaccinated controls (100%) receiving the same challenge displayed clinical erysipelas with high fever, skin lesions, lameness, and death. Mortality in the nonvaccinated control pigs was 50%.

Dosage

Administer 1 dose per pig in the drinking water, to pigs 8 weeks of age or older. If maternal antibody interference exists, or if some pigs did not drink the vaccine treated water, a second dose is recommended 3 to 5 weeks later. Sows or gilts should be revaccinated prior to breeding.

Directions

Vaccine Preparation

Plan vaccination timing to allow thawing of the contents of the vaccine vial in a trickling cool water bath until liquid (usually 30-40 minutes). Shake well and use entire contents immediately. Do not thaw vaccine by removing from the freezer the day before use. This will inactivate the vaccine.

Vaccination via the drinking water:

Conventional water directions (open trough or barrel type [tank] system)

1. Do not thaw vaccine until ready to vaccinate.

2. Do not treat animals with medicated feed containing antimicrobials effective against Erysipelas rhusiopathiae for a minimum of 3 days before and 3 days after the day of vaccination. This will result in a vaccination window totalling 7 days in length.

3. Discontinue sanitizers and disinfectants from drinking water prior to vaccination. Flush watering system with nonchlorinated/nontreated clean water to eliminate any antibacterial agents.

4. Thaw vaccine according to directions.

5. Add number of doses of vaccine equal to or more than the number of pigs to vaccinate, to the appropriate amount of clean, nontreated drinking water (see Caution section).

6. Final solution containing vaccine should be consumed within 6 hours after thawing of vaccine.

Directions for automatic watering systems equipped with proportioner.

Several types of medicators/proportioners are commercially available.

1. Do not thaw vaccine until ready to vaccinate.

2. Do not treat animals with medicated feed containing antimicrobials effective against Erysipelas rhusiopathiae for a minimum of 3 days before and 3 days after the day of vaccination. This will result in a vaccination window totalling 7 days in length.

3. Provide sufficient watering space so that all pigs can drink within a 6 hour time frame.

4. Discontinue sanitizers and disinfectants from drinking water prior to vaccination. Flush watering system with nontreated, clean water to eliminate any antibacterial agents. (This can be accomplished during pre-measurement of stock solution volume requirement in step 6.)

5. Set proportioner to deliver 1 oz. (30 mL) of vaccine solution per 1 gallon (3.8 liters) of drinking water. Regularly clean proportioners internally to remove antibiotics or other contaminants that may impair vaccine viability. Maintain proportioners to manufacturer’s specifications in order to safeguard accurate vaccine administration.

6. Pre-measure the volume of stock solution required for vaccination during a 6 hour period as follows:

a. Fill a clean bucket or other suitable fluid container with water. Be sure to start with more water than the group of swine is expected to consume in a 6 hour period.

b. Insert proportioner draw tube into the water and ensure that the inlet end rests on the bottom of the container.

c. Adjust valves to start proportioned water flowing into the group of swine scheduled for vaccination.

d. After 6 hours, record the volume of water drawn from the container during this period. This 6 hour disappearance volume will be the total volume of clean water, chlorine neutralizer (step 7c), and vaccine to be used on the day of vaccination.

e. Return water supply flow to normal (bypass the proportioner) until ready to vaccinate.

f. NOTE: It is recommended to conduct this pre-measurement at the same time of day as intended for vaccination.

7. Prepare vaccine stock solution as follows:

a. Thaw vaccine according to directions.

b. Add approximately half of the pre-measured amount of clean, disinfectant-free water to the container to be used for stock solution.

c. To ensure vaccine viability, use one or more Reload Pack (Reload Pack DT or Reload Pack DT 5X), which contain the stabilizer sodium thiosulfate, with any source of drinking and stock solution water. A blue dye is also included to facilitate charging water lines and detection of vaccine-containing water (step 8).

d. Add a number of vaccine doses to the stock solution equal to or greater than the number of pigs to vaccinate. Mix thoroughly.

e. Add clean, disinfectant-free water to bring the total volume of this stock solution to the pre-measured 6 hour volume. Mix thoroughly.

8. Vaccinate pigs using the prepared stock-solution as follows:

a. Insert proportioner draw tube into the vaccine stock solution. Ensure that the inlet end is resting on the bottom of the solution container.

b. Adjust water supply valves to direct water through the proportioner.

c. Charge the main water distribution lines throughout the facility being vaccinated. To do this, drain (bleed) water from the valve or drinker on each main line at the end farthest away from the proportioner.

d. Drain water from each main line until the water appears light blue in color.

e. Pigs should consume the vaccine-containing water within 6 hours after thawing the vaccine. Do not medicate or use disinfectants immediately following vaccination.

Ingelvac ERY-ALC Caution

The actual amount of water consumed may vary considerably depending on several factors, including environmental temperature and drinker type. It is recommended to premeasure the actual stock solution volume requirements the day prior to vaccination, during the planned vaccination time period. This should be done in order to ensure that the vaccine is consumed within the 6 hour recommended time frame.

Incompatibility

Do not vaccinate animals which are receiving treatment with antimicrobials effective against Erysipelas rhusiopathiae. Such antimicrobials should be withheld for a minimum of 3 days before and 3 days after the day of vaccination.

Storage

Store frozen at ≤ -60°C. Do not store thawed vaccine. After thawing, shake well and use entire contents immediately.

Withdrawal Period

Vaccinated pigs are not to be harvested for human consumption within 21 days after vaccination.

Disposal

Burn container and all unused contents by a procedure allowed by local, state, and Federal regulations.

Precautions

Avoid direct contact. If human exposure occurs, flush area with clean water, administer first aid, and consult physician immediately. Do not use in pregnant swine or breeding boars. Anaphylactic reactions may occur. Antidote: Epinephrine.

General Recommendations

If swine erysipelas antiserum has been used recently on the pigs, interference with erysipelas vaccination may occur. A period of two weeks after swine erysipelas antiserum usage is generally considered an adequate interval before vaccination. It is recommended that animals being treated with antibiotics not be vaccinated with this vaccine or similar modified live vaccines.

Ingelvac® is a registered trademark of Boehringer Ingelheim Vetmedica GmbH. Used under license.

© 2015 Boehringer Ingelheim Vetmedica, Inc. All Rights Reserved.

Manufactured by Boehringer Ingelheim Vetmedica, Inc., St. Joseph, MO 64506 USA

US Vet. Lic. No. 124

Distributed in Canada by Boehringer Ingelheim (Canada) Ltd., Burlington, Ontario L7L 5H4

250 Doses/100 mL

174309-00

CPN: 1230055.5

BOEHRINGER INGELHEIM (CANADA) LTD.
5180 SOUTH SERVICE ROAD, BURLINGTON, ON, L7L 5H4
Customer Care No.:   800-567-1885
Technical Services No.:   1-877-565-5501
Website:   www.boehringer-ingelheim.ca
Every effort has been made to ensure the accuracy of the Ingelvac ERY-ALC information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.

Copyright © 2017 North American Compendiums. Updated: 2017-08-31

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