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This page contains information on DuraFend for veterinary use.
The information provided typically includes the following:
  • DuraFend Indications
  • Warnings and cautions for DuraFend
  • Direction and dosage information for DuraFend


This treatment applies to the following species:
Company: Durvet

Safe-Guard® (fenbendazole) 0.5%

Type C Medicated Feed

Dewormer for Beef & Dairy Cattle, Horses, Zoo and Wildlife Animals

SAFE-GUARD® (fenbendazole) 0.5% Medicated Dewormer Pellets



0.5% (2.27 g/lb)


Processed grain by-products, calcium carbonate, molasses products, roughage products, silicon dioxide, propionic acid (preservative), acetic acid, natural and artificial flavoring components, sodium propionate (preservative), potassium sorbate (preservative), propylene glycol and citric acid (preservative).


Crude Protein, min


Crude Fat, min


Crude Fiber, max


MEASURING Scoop Included

8 oz (0.23 KG)

CATTLE - Dairy and Beef: For the removal and control of: Lungworms: (Dictyocaulus viviparus); Stomach worms: barberpole worms (Haemonchus contortus), brown stomach worms (Ostertagia ostertagi), small stomach worms (Trichostrongylus axei); Intestinal worms: hookworms (Bunostomum phlebotomum), thread-necked intestinal worms (Nematodirus helvetianus), small intestinal worms (Cooperia punctata, Cooperia oncophora); Bankrupt worms: (Trichostrongylus colubriformis); and Nodular worms: (Oesophagostomum radiatum). HORSES: For the control of: Large strongyles: (Strongylus edentatus, S. equinus, S. vulgaris, Triodontophorus spp); Small strongyles: (Cyathastomum spp., Cylicocyclus spp., Cylicostephanus spp.); Pinworms: (Oxyuris equi); and Ascarids: (Parascaris equorum).

ZOO AND WILDLIFE ANIMALS - Bighorn Sheep: Lung worms: (Protostrongylus spp.). Feral Swine: Kidney worms: (Stephanurus dentatus); Roundworms (Ascaris suum); and Nodular worms (Oesophagostomum dentatum). Ruminants (Subfamilies antilopinae, hippotraginae, and caprinae): Small stomach worm: (Trichostrongylus spp.); Thread-necked intestinal worm: (Nematodirus spp.); Barberpole worm (Haemonchus spp.); and Whipworm: (Trichuris spp.).

Contact Durvet, Inc. for other dewormer products that are cleared for use in Swine and Turkeys.

FEEDING DIRECTIONS - Enclosed scoop measures 8 oz.

CATTLE - DAIRY AND BEEF: 5 mg fenbendazole per kg body weight in a ONE (1) DAY treatment (2.27 mg fenbendazole per pound of bodyweight). Example: 1000 lb. cattle should receive 1 lb. of DuraFend 0.5% in one (1) day. Feed as the sole ration or top dress for one day. No prior withdrawal of feed or water necessary. Under conditions of continued exposure to parasites, retreatment may be needed after 4-6 weeks.

HORSES: For large strongyles, small strongyles and pinworms, the recommended dose is 5 mg fenbendazole per kg body weight (2.27 mg fenbendazole per pound) in a ONE (1) DAY treatment. Example: a 1000-lb horse should receive 1.0 pounds of DuraFend 0.5% in a ONE (1) DAY treatment. For ascarids, the recommended dose is 10 mg fenbendazole per kg body weight (4.54 mg fenbendazole per pound) in a ONE (1) DAY treatment. Example: a 1000-lb horse should receive 2.0 pounds of DuraFend 0.5% in a ONE (1) DAY treatment. All horses must be eating normally to ensure that each animal consumes an adequate amount of medicated feed. Regular deworming at intervals of 6 to 8 weeks may be required due to the possibility of reinfection. Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism.

ZOO AND WILDLIFE ANIMALS - Big Horn Sheep: 10 mg fenbendazole per kg of body weight per day, times (x) 3 days of treatment. Feral Swine: 3 mg fenbendazole per kg of body weight per day, times (x) 3 days of treatment.

Ruminants (subfamilies antilopinae, hippotraginae and caprinae):

2.5 mg fenbendazole per kg of body weight per day, times (x) 3 days of treatment. Example: 250 lb Feral Swine should receive 0.15 lbs. of DuraFend 0.5% per day for 3 days. It is recommended that the user exercise judgmental expertise as needed for retreatment within six (6) weeks. This would depend upon the conditions of treated animals and ambient temperatures. Once correct proportions of Durafend 0.5% and feed ingredients have been established and blended, use as complete feed.

WARNINGS: KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN. NOT FOR USE IN HUMANS. The Material Safety Data Sheet (MSDS) contains more detailed occupational safety information. To report adverse effects, obtain an MSDS or for assistance, contact customer service at 1-800-441-8272.

Dairy and Beef - Residue warning - Cattle must not be slaughtered within 13 days following last treatment. There are no known contradictions to the use of the drug in cattle. For dairy cattle, there is no milk withdrawal period. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal. Horses - Do not use in horses intended for human consumption. Zoo and Wildlife Animals - Residue warning - Do not use 14 days before or during the hunting season. Animal Safety: No contradictions for the use of fenbendazole in a zoo environment have been established. Administration to breeding and pregnant ruminants at 2 to 22 times the recommended dose has had no apparent adverse effect.

Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.

Safe-Guard is properly of lntervet International B.V. or affiliated companies or licensors and are protected by copyrights, trademark and other intellectual properly laws.

©2010 Intervet International B.V. All rights reserved.


Manufactured for Durvet, Inc., Blue Springs, MO 64014




1 LB (0.45 KG)

ISS 0916

5 LB (2.27 KG)

ISS 0916

10 LB (4.54 KG)

ISS 0916

25 LB (11.34 KG)

ISS 0916

CPN: 1084395.0

Telephone:   816-229-9101
Toll-Free:   800-821-5570
Fax:   816-224-3080
Every effort has been made to ensure the accuracy of the DuraFend information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2020 Animalytix LLC. Updated: 2020-10-21