Borgal (Canada)This page contains information on Borgal for veterinary use.
The information provided typically includes the following:
- Borgal Indications
- Warnings and cautions for Borgal
- Direction and dosage information for Borgal
BorgalThis treatment applies to the following species:
Trimethoprim and sulfadoxine injectable solution
VETERINARY USE ONLY
Each mL contains:
trimethoprime Ph. Eur.
sulfadoxine Ph. Eur.
sodium hydroxide Ph. Eur.
glycerinformal Mfr. Std.
water for injection Ph. Eur.
BORGAL contains trimethoprim (a synthetic antibacterial), and sulfadoxine (a sulfonamide). The two components of BORGAL produce a sequential double blockade of bacterial metabolism, giving a level of activity many times greater than that obtained from either drug alone.
BORGAL provides effective antibacterial activity against a wide range of infections caused by Gram-positive and Gram-negative bacteria.
BORGAL has shown activity in vitro against the following organisms:
Very Sensitive Organisms
Staphylococcus aureus including penicillinase-producing organisms
Moderately Sensitive Organisms
BORGAL may be used in cattle and swine where potent antibacterial action against a wide range of infections caused by sensitive organisms is required.
BORGAL is indicated in cattle for the treatment of:
RESPIRATORY TRACT INFECTIONS - bacterial pneumonias including bovine pneumonic pasteurellosis (shipping fever).
ALIMENTARY TRACT INFECTIONS - primarily enteric and septicaemic colibacillosis and salmonellosis.
OTHER INFECTIONS - infectious pododermatitis (foot rot) and septicaemias.
BORGAL is indicated in swine for the treatment of:
RESPIRATORY TRACT INFECTIONS - bacterial pneumonias.
ALIMENTARY TRACT INFECTIONS - colibacillosis and post-weaning scours.
OTHER INFECTIONS - mastitis-metritis-agalactia syndrome of sows (MMA) and bacterial arthritis.
Borgal Dosage And Administration
BORGAL should be administered at a dose rate of 16 mg/kg body weight (3 mL per 45 kg [100 lb]) daily. In piglets weighing less than 4.5 kg (10 lb) do not exceed a dose of 0.5 mL.
Intramuscular injection is recommended for cattle and swine, but if a particularly rapid response is required in acute infections, BORGAL can be administered by slow intravenous injection.
Treatment should continue for 2-3 days after symptoms have subsided. The usual course of treatment is for not longer than 5 consecutive days.
BORGAL should not be used in cattle or swine showing marked liver parenchymal damage or blood dyscrasias, nor in those with a history of sulfonamide sensitivity.
With intravenous therapy generally, and sulfonamides in particular, hypersensitivity reactions can occur and should be appropriately treated with corticosteroids or epinephrine.
Temporary, local, irritating swellings are encountered occasionally after intramuscular injection of BORGAL.
Milk taken from treated animals during treatment and within 96 hours after the latest treatment with this drug must not be used as food. Treated animals must not be slaughtered for use in food for at least 10 days after the latest treatment with this drug. Keep out of reach of children.
No significant adverse reactions have been reported.
Store at room temperature, below 25°C.
Bottles of 100 mL, 250 mL and 500 mL
Intervet Canada Corp., 16750, route Transcanadienne, Kirkland QC, H9H 4M7
Intervet Canada Corp. is a subsidiary of Merck & Co., Inc
Version 02 February 2012
® Registered trademark of Intervet International B.V. Used under license.
Intervet Canada Corp.
16750 ROUTE TRANSCANADIENNE, KIRKLAND, QC, H9H 4M7
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