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advantus (imidacloprid) soft chew

This page contains information on advantus (imidacloprid) soft chew for veterinary use.
The information provided typically includes the following:
  • advantus (imidacloprid) soft chew Indications
  • Warnings and cautions for advantus (imidacloprid) soft chew
  • Direction and dosage information for advantus (imidacloprid) soft chew

advantus (imidacloprid) soft chew

This treatment applies to the following species:
Company: Elanco US

Current label information has not been provided by the product owner.

This information is provided as a service to our users.

advantus is a flavored soft chew for dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater.

Active Ingredients

advantus contains 7.5 mg or 37.5 mg of imidacloprid.

Use: advantus kills adult fleas and is indicated for the treatment of flea infestations on dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater.


Not for human use. Keep this and all drugs out of the reach of children.

Keep advantus in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.

Side Effects

Side effects seen with this drug include vomiting, decreased appetite, decreased energy, soft stools and difficulty walking.

Directions: You should weigh your dog before giving this medication to make sure you are using the right size for your dog. Do not give to puppies younger than 10 weeks of age or to dogs weighing less than 4 pounds. Do not give more than one tablet a day.

Use the table to find the right dose for your dog:

Dosing Table

Body Weight


Soft Chew Strength

4-22 lbs

One Soft Chew

7.5 mg imidacloprid

23-110 lbs

One Soft Chew

37.5 mg imidacloprid

*If your dog becomes re-infested, you can safely repeat treatment as often as once a day.

To give advantus, place the soft chew directly in your dog’s mouth or allow your dog to take the soft chew from your hand. Watch closely to ensure your dog swallows the soft chew.

A single dose kills adult fleas on your dog. Because advantus does not have an effect on fleas in the environment, your dog may become re-infested with fleas. If your dog becomes re-infested, you can safely repeat treatment as often as once a day. Contact your veterinarian if you have any questions about flea infestations on your dog.

Treat all pets in your household with a flea protection product. advantus should only be given to dogs.

Questions/Comments? For product questions or to report side effects, call Elanco at 888-545-5973. For additional information about reporting side effects for animal drugs, contact FDA at 1-888-FDA-VETS or

Other Information:

● Contact your veterinarian if your dog ingests more than the recommended dose of advantus.

● advantus has not been tested in pregnant or nursing dogs.

● advantus starts to kill fleas within 1 hour. A study demonstrated that advantus achieves greater than 96% effectiveness against adult fleas within 4 hours.

● advantus may be used together with other products, including heartworm preventatives, corticosteroids, antibiotics, vaccines, deworming medications and shampoos.

● advantus does not protect against ticks or mosquitoes.

Flea Infestations on Dogs: Treatment of flea infestations is important to your dog’s health. Fleas in your dog’s environment can re-infest your dog. Therefore, you may need to treat with advantus more than one time. The following diagram illustrates the flea’s life cycle and where advantus works:

Fleas reproduce rapidly. A single female flea may produce up to 2,000 eggs over her lifetime. Eggs hatch and may grow into adults in only three weeks. Adult female fleas feed by ingesting blood from your dog and lay eggs that drop off from your dog’s coat. Within days, larvae hatch from these eggs and live undetected in your dog’s surroundings, such as in the carpet and bedding. Fleas can emerge to re-infest your pet, continuing the life cycle. When these new fleas are seen on your dog, treat with advantus.

If you have any questions about flea treatment or medical problems associated with flea infestations, consult your veterinarian.

Storage Information: Store at temperatures between 68° and 77°F (20°-25°C).

How Supplied

advantus is available in two strengths: 7.5 mg or 37.5 mg imidacloprid. Both strengths are packaged in 7 count bottles containing 7 flavored soft chews or 30 count bottles containing 30 flavored soft chews.

Approved by FDA under NADA # 141-435

Manufactured for:

Elanco US Inc., Greenfield, IN 46140 U.S.A.

Revised: January 2022

Made in Spain.

advantus, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates.

© 2022 Elanco or its affiliates



CPN: 1131112.0

Customer Service:   317-276-1262
Technical Service:   800-428-4441
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Copyright © 2023 Animalytix LLC. Updated: 2023-05-29