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Triumeq: 7 things you should know

Medically reviewed by Carmen Pope, BPharm. Last updated on July 13, 2023.

1. How it works

2. Upsides

3. Downsides

If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:

Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects

4. Bottom Line

Triumeq is a fixed-dose combination tablet that contains three antivirals: abacavir, dolutegravir, and lamivudine, which may be used to treat HIV-1 infection in adults and children weighing at least 10 kg (22 pounds). It is taken as a single tablet once a day and is usually well-tolerated, with side effects such as fatigue, headache, and nausea reported by less than 3% of people who take it. Triumeq is not suitable for people who test positive for the HLA-B5701 gene.

5. Tips

6. Response and effectiveness

7. Interactions

Medicines that interact with Triumeq may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with Triumeq. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed.

Common medications that may interact with Triumeq include:

Indigestion remedies (antacids) that contain aluminum carbonate/hydroxide, magnesium hydroxide, or calcium carbonate should be taken at least 2 hours before or 2 hours after Triumeq. Antacids decrease the absorption and blood levels of dolutegravir, one of the medicines in Triumeq.

Because of a decrease in dolutegravir concentrations, an additional 50mg dolutegravir tablet, separated 12 hours from Triumeq, should be taken by people who are coadministered efavirenz, fosamprenavir/ritonavir, tipranavir/ritonavir, carbamazepine, or rifampin.

Note that this list is not all-inclusive and includes only common medications that may interact with Triumeq. You should refer to the prescribing information for Triumeq for a complete list of interactions.


Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Triumeq only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2024 Revision date: July 12, 2023.