Z-COF 12 Side Effects

Generic name: dextromethorphan / guaifenesin / pseudoephedrine

Medically reviewed by Drugs.com. Last updated on Jun 19, 2022.

Note: This document contains side effect information about dextromethorphan / guaifenesin / pseudoephedrine. Some dosage forms listed on this page may not apply to the brand name Z-COF 12.

Applies to dextromethorphan / guaifenesin / pseudoephedrine: oral capsule, oral liquid, oral tablet, oral tablet extended release.

Warning

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have:

fast or uneven heart rate;
severe dizziness or anxiety, feeling like you might pass out;
severe headache;
mood changes;
fever; or
dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, uneven heartbeats, seizure).

Common side effects may include:

diarrhea;
dizziness, drowsiness;
sleep problems (insomnia); or
feeling nervous, restless, or irritable.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to dextromethorphan/guaifenesin/pseudoephedrine: oral capsule, oral liquid, oral suspension, oral suspension extended release, oral syrup, oral tablet, oral tablet extended release.