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Vimseltinib Side Effects

Applies to vimseltinib: oral capsules.

Side effects include:

Most common adverse effects (≥20%): Increased AST concentrations, increased ALT concentrations, periorbital edema, fatigue, rash, increased cholesterol, peripheral edema, facial edema, decreased neutrophils, decreased leukocytes, pruritus.

For healthcare professionals

Applies to vimseltinib: oral capsule.

General adverse events

The most common adverse reactions included increased AST, periorbital edema, fatigue, rash, increased cholesterol, peripheral edema, face edema, decreased neutrophils, decreased leukocytes, pruritus, and increased ALT.[Ref]

Cardiovascular

Dermatologic

Hematologic

Hepatic

During clinical trials, grade 3 increases in AST and ALT were reported in 2% and 1% of patients, respectively. Dose interruptions and reductions due to increased AST/ALT occurred in 2% and 1% of patients, respectively; at least 1 patient discontinued therapy due to grade 3 increased AST.

Musculoskeletal

Nervous system

Ocular

Other

Renal

References

1. (2025) "Product Information. Romvimza (vimseltinib)." Deciphera Pharmaceuticals

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Further information

Vimseltinib side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.