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Topicycline Side Effects

Generic Name: tetracycline topical

Note: This document contains side effect information about tetracycline topical. Some of the dosage forms listed on this page may not apply to the brand name Topicycline.

Applies to tetracycline topical: topical ointment, topical solution


Dermatitis has been reported rarely with topical application of tetracycline. One-third of patients may experience a stinging and burning sensation lasting no more than a few minutes. A faint yellowing of the skin has been reported, especially around the hair roots.[Ref]


Tetracycline topical (the active ingredient contained in Topicycline) is generally well tolerated. Side effects reported with systemic administered tetracycline such as gastrointestinal complaints, vaginitis, hematologic abnormalities, dental, and skeletal disorders have not been reported and are unlikely to occur with topical administration.[Ref]


1. "Product Information. Achromycin (tetracycline)." Lederle Laboratories, Wayne, NJ.

2. Fisher AA "Adverse reactions to topical clindamycin, erythromycin and tetracycline." Cutis 32 (1983): 415,419,424,428

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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